Research Output per year
Research Output 2017 2019
- 1 - 50 out of 53 results
- Publication Year, Title (descending)
2019
A balancing act: PHLPP2 fine tunes AKT activity and MYC stability in prostate cancer
Toivanen, R. & Furic, L., 3 Jun 2019, In : Journal of Cell Biology. 218, 6, p. 1771-1772 2 p.Research output: Contribution to journal › Editorial › Other › peer-review
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer
Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, , Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target
Lee, R. S., Zhang, L., Berger, A., Lawrence, M. G., Song, J., Niranjan, B., Davies, R. G., Lister, N. L., Sandhu, S. K., Rubin, M. A., Risbridger, G. P., Taylor, R. A., Rickman, D. S., Horvath, L. G. & Daly, R. J., 1 Apr 2019, In : Neoplasia. 21, 4, p. 389-400 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Characterization of the Src-regulated kinome identifies SGK1 as a key mediator of Src-induced transformation
Ma, X., Zhang, L., Song, J., Nguyen, E., Lee, R. S., Rodgers, S. J., Li, F., Huang, C., Schittenhelm, R. B., Chan, H., Chheang, C., Wu, J., Brown, K. K., Mitchell, C. A., Simpson, K. J. & Daly, R. J., 17 Jan 2019, In : Nature Communications. 10, 1, 16 p., 296.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Effective angiogenesis requires regulation of phosphoinositide signaling
Davies, E. M., Gurung, R., Le, K. Q. & Mitchell, C. A., Jan 2019, In : Advances in Biological Regulation. 71, p. 69-78 10 p.Research output: Contribution to journal › Article › Research › peer-review
Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer
Porter, L. H., Lawrence, M. G., Wang, H., Clark, A. K., Bakshi, A., Obinata, D., Goode, D., Papargiris, M., Clouston, D., Ryan, A., Norden, S., Corey, E., Nelson, P. S., Isaacs, J. T., Grummet, J., Kourambas, J., Sandhu, S., Murphy, D. G., Pook, D., Frydenberg, M. & 2 others, , 1 Aug 2019, In : Prostate. 79, 11, p. 1326-1337 12 p.Research output: Contribution to journal › Article › Research › peer-review
Gastrointestinal dysfunction in patients and mice expressing the autism-associated r451c mutation in neuroligin-3
Hosie, S., Ellis, M., Swaminathan, M., Ramalhosa, F., Seger, G. O., Balasuriya, G. K., Gillberg, C., Råstam, M., Churilov, L., McKeown, S. J., Yalcinkaya, N., Urvil, P., Savidge, T., Bell, C. A., Bodin, O., Wood, J., Franks, A. E., Bornstein, J. C. & Hill-Yardin, E. L., Jul 2019, In : Autism Research. 12, 7, p. 1043-1056 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Generally applicable transcriptome-wide analysis of translation using anota2seq
Oertlin, C., Lorent, J., Murie, C., Furic, L., Topisirovic, I. & Larsson, O., 9 Jul 2019, In : Nucleic Acids Research. 47, 12, 15 p., e70.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Identification of Metabolically Distinct Adipocyte Progenitor Cells in Human Adipose Tissues
Raajendiran, A., Ooi, G., Bayliss, J., O'Brien, P. E., Schittenhelm, R. B., Clark, A. K., Taylor, R. A., Rodeheffer, M. S., Burton, P. R. & Watt, M. J., 30 Apr 2019, In : Cell Reports. 27, 5, p. 1528-1540 13 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
iLearn: an integrated platform and meta-learner for feature engineering, machine-learning analysis and modeling of DNA, RNA and protein sequence data
Chen, Z., Zhao, P., Li, F., Marquez-Lago, T. T., Leier, A., Revote, J., Zhu, Y., Powell, D. R., Akutsu, T., Webb, G. I., Chou, K-C., Smith, A. I., Daly, R. J., Li, J. & Song, J., 24 Apr 2019, (Accepted/In press) In : Briefings in Bioinformatics. 11 p., bbz041.Research output: Contribution to journal › Article › Research › peer-review
Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment
Nguyen, E. V., Pereira, B. A., Lawrence, M. G., Ma, X., Rebello, R. J., Chan, H., Niranjan, B., Wu, Y., Ellem, S., Guan, X., Wu, J., Skhinas, J. N., Cox, T. R., Risbridger, G. P., Taylor, R. A., Lister, N. L. & Daly, R. J., 1 Jul 2019, In : Molecular and Cellular Proteomics. 18, 7, p. 1410-1427 18 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
Lee, Y. R., Chen, M., Lee, J. D., Zhang, J., Lin, S. Y., Fu, T. M., Chen, H., Ishikawa, T., Chiang, S. Y., Katon, J., Zhang, Y., Shulga, Y. V., Bester, A. C., Fung, J., Monteleone, E., Wan, L., Shen, C., Hsu, C. H., Papa, A., Clohessy, J. G. & 7 others, , 17 May 2019, In : Science. 364, 6441, 15 p., eaau0159.Research output: Contribution to journal › Article › Research › peer-review
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer
Watt, M. J., Clark, A. K., Selth, L. A., Haynes, V. R., Lister, N., Rebello, R., Porter, L. H., Niranjan, B., Whitby, S. T., Lo, J., Huang, C., Schittenhelm, R. B., Anderson, K. E., Furic, L., Wijayaratne, P. R., Matzaris, M., Montgomery, M. K., Papargiris, M., Norden, S., Febbraio, M. & 4 others, , 6 Feb 2019, In : Science Translational Medicine. 11, 478, 12 p., eaau5758.Research output: Contribution to journal › Article › Research › peer-review
The influence of BRCA2 mutation on localized prostate cancer
Taylor, R. A., Fraser, M., Rebello, R. J., Boutros, P. C., Murphy, D. G., Bristow, R. G. & Risbridger, G. P., 1 May 2019, In : Nature Reviews Urology. 16, 5, p. 281-290 10 p.Research output: Contribution to journal › Review Article › Research › peer-review
The PTEN⁻PI3K Axis in Cancer
Papa, A. & Pandolfi, P. P., 17 Apr 2019, In : Biomolecules. 9, 4, 11 p., 153.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Tissue engineered human prostate microtissues reveal key role of mast cell-derived tryptase in potentiating cancer-associated fibroblast (CAF)-induced morphometric transition in vitro
Pereira, B. A., Lister, N. L., Hashimoto, K., Teng, L., Flandes-Iparraguirre, M., Eder, A., Sanchez-Herrero, A., Niranjan, B., Melbourne Urological Research Alliance (MURAL), Frydenberg, M., Papargiris, M. M., Lawrence, M. G., Taylor, R. A., Hutmacher, D. W., Ellem, S. J., Risbridger, G. P. & De-Juan-Pardo, E. M., 1 Mar 2019, In : Biomaterials. 197, p. 72-85 14 p.Research output: Contribution to journal › Article › Research › peer-review
V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss
Mohammad, A. H., Assadian, S., Couture, F., Lefebvre, K. J., El-Assaad, W., Barrs, V., Ouellet, V., Boulay, P. L., Yang, J., Latour, M., Furic, L., Muller, W., Sonenberg, N., Mes-Masson, A. M., Saad, F., Day, R. & Teodoro, J. G., 13 Aug 2019, In : Oncotarget. 10, 48, p. 4923-4936 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
β-catenin ablation exacerbates polycystic kidney disease progression
Conduit, S. E., Hakim, S., Feeney, S. J., Ooms, L. M., Dyson, J. M., Abud, H. E. & Mitchell, C. A., 15 Jan 2019, In : Human Molecular Genetics. 28, 2, p. 230-244 15 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
2018
Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice
Holt, L. J., Brandon, A. E., Small, L., Suryana, E., Preston, E., Wilks, D., Mokbel, N., Coles, C. A., White, J. D., Turner, N., Daly, R. J. & Cooney, G. J., 1 Mar 2018, In : Endocrinology. 159, 3, p. 1339-1351 13 p.Research output: Contribution to journal › Article › Research › peer-review
AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965
Dite, T. A., Langendorf, C. G., Hoque, A., Galic, S., Rebello, R. J., Ovens, A. J., Lindqvist, L. M., Ngoei, K. R. W., Ling, N. X. Y., Furic, L., Kemp, B. E., Scott, J. W. & Oakhill, J. S., 1 Jan 2018, In : Journal of Biological Chemistry. 293, 23, p. 8874-8885 12 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Computational modeling of the dynamics of spatiotemporal rho gtpase signaling: A systematic review
Khatibi, S., Rios, K. I. & Nguyen, L. K., 2018, Rho GTPases. Rivero, F. (ed.). New York, NY: Humana Press, p. 3-20 18 p. (Methods in Molecular Biology; vol. 1821).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Cross-talk between protein synthesis, energy metabolism and autophagy in cancer
Lindqvist, L. M., Tandoc, K., Topisirovic, I. & Furic, L., 1 Feb 2018, In : Current Opinion in Genetics and Development. 48, p. 104-111 8 p.Research output: Contribution to journal › Review Article › Research › peer-review
Open Access
File
Differential expression profiles of conserved Snail transcription factors in the mouse testis
Micati, D. J., Hime, G. R., McLaughlin, E. A., Abud, H. E. & Loveland, K. L., 1 Mar 2018, In : Andrology. 6, 2, p. 362-373 12 p.Research output: Contribution to journal › Article › Research › peer-review
Diverse bacterial species contribute to antibiotic-associated diarrhoea and gastrointestinal damage
Larcombe, S., Hutton, M. L., Riley, T. V., Abud, H. E. & Lyras, D., Nov 2018, In : Journal of Infection. 77, 5, p. 417-426 10 p.Research output: Contribution to journal › Article › Research › peer-review
Effect of FAK inhibitor VS-6063 (defactinib) on docetaxel efficacy in prostate cancer
Lin, H. M., Lee, B. Y., Castillo, L., Spielman, C., Grogan, J., Yeung, N. K., Kench, J. G., Stricker, P. D., Haynes, A. M., Centenera, M. M., Butler, L. M., Shreeve, S. M., Horvath, L. G. & Daly, R. J., 1 Mar 2018, In : Prostate. 78, 4, p. 308-317 10 p.Research output: Contribution to journal › Article › Research › peer-review
Enduring epigenetic landmarks define the cancer microenvironment
Pidsley, R., Lawrence, M. G., Zotenko, E., Niranjan, B., Statham, A., Song, J., Chabanon, R. M., Qu, W., Wang, H., Richards, M., Nair, S. S., Armstrong, N., Nim, H. T., Papargiris, M., Balanathan, P., French, H., Peters, T., Norden, S., Ryan, A., Pedersen, J. & 9 others, , 1 May 2018, In : Genome Research. 28, 5, p. 625-638 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Germline variation at 8q24 and prostate cancer risk in men of European ancestry
Matejcic, M., Saunders, E. J., Dadaev, T., Brook, M. N., Wang, K., Sheng, X., Al Olama, A. A., Schumacher, F., Ingles, S. A., Govindasami, K., Benlloch, S., Berndt, S., Albanes, D., Koutros, S., Muir, K., Stevens, V. L., Gapstur, S. M., Tangen, C. M., Batra, J., Clements, J. & 7 others, , 5 Nov 2018, In : Nature Communications. 9, 11 p., 382.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance
La, H. M., Chan, A-L., Legrand, J. M. D., Rossello, F. J., Gangemi, C. G., Papa, A., Cheng, Q., Morand, E. F. & Hobbs, R. M., 1 Sep 2018, In : Development. 145, 18, dev165324.Research output: Contribution to journal › Article › Research › peer-review
Helicobacter pylori type IV secretion system and its adhesin subunit, CagL, mediate potent inflammatory responses in primary human endothelial cells
Tafreshi, M., Guan, J., Gorrell, R. J., Chew, N., Xin, V., Deswaerte, V., Rohde, M., Daly, R. J., Peek Jr, R. M., Jenkins, B. J., Davies, E. M. & Kwok, T., 6 Feb 2018, In : Frontiers in Cellular and Infection Microbiology. 8, FEB, 15 p., 22.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Identification of novel response and predictive biomarkers to Hsp90 inhibitors through proteomic profiling of patient-derived prostate tumor explants
Nguyen, E. V., Centenera, M. M., Moldovan, M., Das, R., Irani, S., Vincent, A. D., Chan, H., Horvath, L. G., Lynn, D. J., Daly, R. J. & Butler, L. M., 1 Aug 2018, In : Molecular and Cellular Proteomics. 17, 8, p. 1470-1486 17 p.Research output: Contribution to journal › Article › Research › peer-review
Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth
Pearson, H. B., Li, J., Meniel, V. S., Fennell, C. M., Waring, P., Montgomery, K. G., Rebello, R. J., Macpherson, A. A., Koushyar, S., Furic, L., Cullinane, C., Clarkson, R. W., Smalley, M. J., Simpson, K. J., Phesse, T. J., Shepherd, P. R., Humbert, P. O., Sansom, O. J. & Phillips, W. A., 1 Jun 2018, In : Cancer Discovery. 8, 6, p. 764-779 16 p.Research output: Contribution to journal › Article › Research › peer-review
Impact of the anticancer drug nt157 on tyrosine kinase signaling networks
Su, S-P., Flashner-Abramson, E., Klein, S., Gal, M., Lee, R. S., Wu, J., Levitzki, A. & Daly, R. J., 1 May 2018, In : Molecular Cancer Therapeutics. 17, 5, p. 931-942 12 p.Research output: Contribution to journal › Article › Research › peer-review
Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma
Voon, H. P. J., Udugama, M., Lin, W., Hii, L., Law, R. H. P., Steer, D. L., Das, P. P., Mann, J. R. & Wong, L. H., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 3142.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner
O'Reilly, L. A., Putoczki, T. L., Mielke, L. A., Low, J. T., Lin, A., Preaudet, A., Herold, M. J., Yaprianto, K., Tai, L., Kueh, A., Pacini, G., Ferrero, R. L., Gugasyan, R., Hu, Y., Christie, M., Wilcox, S., Grumont, R., Griffin, M. D. W., O'Connor, L., Smyth, G. K. & 4 others, , 20 Mar 2018, In : Immunity. 48, 3, p. 570-583 14 p.Research output: Contribution to journal › Article › Research › peer-review
MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer
Lin, H. M., Nikolic, I., Yang, J., Castillo, L., Deng, N., Chan, C. L., Yeung, N. K., Dodson, E., Elsworth, B., Spielman, C., Lee, B. Y., Boyer, Z., Simpson, K. J., Daly, R. J., Horvath, L. G. & Swarbrick, A., 1 Dec 2018, In : Scientific Reports. 8, 1, 12 p., 7820.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Modelling intestinal carcinogenesis using in vitro organoid cultures
Jardé, T., Kerr, G., Akhtar, R. & Abud, H. E., 2018, Methods in Molecular Biology. Humana Press, Vol. 1725. p. 41-52 12 p. (Methods in Molecular Biology; vol. 1725).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy
Lawrence, M. G., Obinata, D., Sandhu, S., Selth, L. A., Wong, S. Q., Porter, L. H., Lister, N., Pook, D., Pezaro, C. J., Goode, D. L., Rebello, R. J., Clark, A. K., Papargiris, M., Van Gramberg, J., Hanson, A. R., Banks, P., Wang, H., Niranjan, B., Keerthikumar, S., Hedwards, S. & 32 others, , 1 Nov 2018, In : European Urology. 74, 5, p. 562-572 11 p.Research output: Contribution to journal › Article › Research › peer-review
PIM activity in tumours: A key node of therapy resistance
Rebello, R. J., Huglo, A. V. & Furic, L., Jan 2018, In : Advances in Biological Regulation. 67, p. 163-169 7 p.Research output: Contribution to journal › Review Article › Research › peer-review
Preclinical models of prostate cancer: Patient-derived xenografts, organoids, and other explant models
Risbridger, G. P., Toivanen, R. & Taylor, R. A., 1 Aug 2018, In : Cold Spring Harbor Perspectives in Medicine. 8, 8, 14 p., a030536.Research output: Contribution to journal › Article › Other › peer-review
Open Access
File
Role of activin C in normal ovaries and granulosa cell tumours of mice and humans
Reader, K. L., Marino, F. E., Nicholson, H. D., Risbridger, G. P. & Gold, E. J., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 7, p. 958-968 11 p., RD17250.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
The pseudokinases SgK269 and SgK223: A novel oncogenic alliance in human cancer
O'Rourke, R. L. & Daly, R. J., 2018, In : Cell Adhesion and Migration. 12, 6, p. 524-528 5 p.Research output: Contribution to journal › Article › Research › peer-review
Twenty years of bioinformatics research for protease-specific substrate and cleavage site prediction: a comprehensive revisit and benchmarking of existing methods
Li, F., Wang, Y., Li, C., Marquez-Lago, T. T., Leier, A., Rawlings, N. D., Haffari, G., Revote, J., Akutsu, T., Chou, K-C., Purcell, A. W., Pike, R. N., Webb, G. I., Smith, A. I., Lithgow, T., Daly, R. J., Whisstock, J. C. & Song, J., 2018, (Accepted/In press) In : Briefings in Bioinformatics. 17 p., bby077.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Uncovering bistability in the Rac1/RhoA signalling network through integrating computational modelling and experimentation
von Kriegsheim, A. & Nguyen, L. K., 2018, Rho GTPases. Rivero, F. (ed.). New York, NY: Humana Press, p. 21-36 16 p. (Methods in Molecular Biology; vol. 1821).Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review
2017
A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma
Conduit, SE., Ramaswamy, V., Remke, M., Watkins, DN., Wainwright, BJ., Taylor, MD., Mitchell, CA. & Dyson, JM., 26 Oct 2017, In : Oncogene. 36, 43, p. 5969-5984 16 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity
Chan, F. L., Vinod, B., Novy, K., Schittenhelm, R. B., Huang, C., Udugama, M., Nunez-Iglesias, J., Lin, J. I., Hii, L., Chan, J., Pickett, H. A., Daly, R. J. & Wong, L. H., 1 Dec 2017, In : Nucleic Acids Research. 45, 21, p. 12340-12353 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Human milk bioactivity: lessons from the evolution of lactation
Sharp, J., Watt, A., Lefèvre, C. & Nicholas, K., Apr 2017, In : Australian Biochemist. 48, 1, p. 13-18 6 p.Research output: Contribution to journal › Article › Research
Open Access
File
Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death
Hirst, C. S., Stamp, L. A., Bergner, A. J., Hao, M. M., Tran, M., Morgan, J., Dutschmann, M., Allen, A. M., Paxinos, G., Furlong, T., McKeown, S. J. & Young, H. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16676.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori
Srikhanta, Y. N., Gorrell, R. J., Power, P., Tsyganov, K., Boitano, M., Clark, T. A., Korlach, J., Hartland, E. L., Jennings, M. P. & Kwok, T., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16140.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes
Fleuren, E. D. G., Vlenterie, M., Van Der Graaf, W. T. A., Hillebrandt-Roeffen, M. H. S., Blackburn, J., Ma, X., Chan, H., Magias, M. C., Van Erp, A., Van Houdt, L., Cebeci, S. A. S., Van De Ven, A., Flucke, U. E., Heyer, E. E., Thomas, D. M., Lord, C. J., Marini, K. D., Vaghjiani, V., Mercer, T. R., Cain, J. E. & 3 others, , 15 Aug 2017, In : Cancer Research. 77, 16, p. 4279-4292 14 p.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File
Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association
Patel, O., Griffin, M. D. W., Panjikar, S., Dai, W., Ma, X., Chan, H., Zheng, C., Kropp, A., Murphy, J. M., Daly, R. J. & Lucet, I. S., 1 Dec 2017, In : Nature Communications. 8, 1, 15 p., 1157.Research output: Contribution to journal › Article › Research › peer-review
Open Access
File