Research Output

2020

Accelerated brain aging towards transcriptional inversion in a zebrafish model of the K115fs mutation of human PSEN2

Hin, N., Newman, M., Kaslin, J., Douek, A. M., Lumsden, A., Nik, S. H. M., Dong, Y., Zhou, X. F., Manucat-Tan, N. B., Ludington, A., Adelson, D. L., Pederson, S. & Lardelli, M., 24 Jan 2020, In : PLoS ONE. 15, 1, 36 p., e0227258.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

A collection of genetic mouse lines and related tools for inducible and reversible intersectional mis-expression

Ahmadzadeh, E., Bayin, N. S., Qu, X., Singh, A., Madisen, L., Stephen, D., Zeng, H., Joyner, A. L. & Rosello-Diez, A., 28 May 2020, In : Development. 147, 10, 12 p., 186650.

Research output: Contribution to journalArticleResearchpeer-review

A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture

Grubman, A., Vandekolk, T. H., Schröder, J., Sun, G., Hatwell-Humble, J., Chan, J., Oksanen, M., Lehtonen, S., Hunt, C., Koistinaho, J. E., Nilsson, S. K., Haynes, J. M., Pouton, C. W. & Polo, J. M., 9 Jun 2020, In : Stem Cell Reports. 14, 6, p. 1018-1032 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery

Oikari, L. E., Pandit, R., Stewart, R., Cuní-López, C., Quek, H., Sutharsan, R., Rantanen, L. M., Oksanen, M., Lehtonen, S., de Boer, C. M., Polo, J. M., Götz, J., Koistinaho, J. & White, A. R., 12 May 2020, In : Stem Cell Reports. 14, 5, p. 924-939 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar

del Monte-Nieto, G., Fischer, J. W., Gorski, D. J., Harvey, R. P. & Kovacic, J. C., 5 May 2020, In : Journal of the American College of Cardiology. 75, 17, p. 2169-2188 20 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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Bioinspired polynorepinephrine nanoparticles as an efficient vehicle for enhanced drug delivery

Lu, Z., Douek, A. M., Rozario, A. M., Tabor, R. F., Kaslin, J., Follink, B. & Teo, B. M., 1 Jan 2020, In : Journal of Materials Chemistry B. 8, 5, p. 961-968 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Correction: Neurogenesis in the inner ear: the zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood (Development (Cambridge, England) (2020) 147 7 PII: dev191775)

Schwarzer, S., Asokan, N., Bludau, O., Chae, J., Kuscha, V., Kaslin, J. & Hans, S., 4 May 2020, In : Development (Cambridge). 147, 9, 1 p., dev191775.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Discussing limb development and regeneration in Barcelona: The future is at hand

Rosello-Diez, A. & Whited, J. L., Feb 2020, In : Developmental Dynamics. 249, 2, p. 160-163 4 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
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Effect of Ataluren on dystrophin mutations

Berger, J., Li, M., Berger, S., Meilak, M., Rientjes, J. & Currie, P. D., Jun 2020, In : Journal of Cellular and Molecular Medicine. 24, 12, p. 6680-6689 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Elevated circulating HtrA4 in preeclampsia may alter endothelial expression of senescence genes

Wang, Y., Lim, R. & Nie, G., 15 Jan 2020, In : Placenta. 90, p. 71-81 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling

Julier, Z., Karami, R., Nayer, B., Lu, Y-Z., Park, A. J., Maruyama, K., Kuhn, G. A., Müller, R., Akira, S. & Martino, M. M., 12 Jun 2020, In : Science Advances. 6, 24, 13 p., eaba7602.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Erratum: A Neuroethics Framework for the Australian Brain Initiative (Neuron (2019) 101(3) (365–369), (S0896627319300054), (10.1016/j.neuron.2019.01.004))

Australian Brain Alliance, 8 Jan 2020, In : Neuron. 105, 1, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
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Extensive Connectivity Between the Medial Pulvinar and the Cortex Revealed in the Marmoset Monkey

Homman-Ludiye, J., Mundinano, I. C., Kwan, W. C. & Bourne, J. A., Mar 2020, In : Cerebral Cortex. 30, 3, p. 1797-1812 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Frontline Science: Dynamic cellular and subcellular features of migrating leukocytes revealed by in vivo lattice lightsheet microscopy

Manley, H. R., Potter, D. L., Heddleston, J. M., Chew, T-L., Keightley, M. C. & Lieschke, G. J., 23 Apr 2020, (Accepted/In press) In : Journal of leukocyte biology. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional diversity between HSP70 paralogs caused by variable interactions with specific co-chaperones

Serlidaki, D., van Waarde, M. A. W. H., Rohland, L., Wentink, A. S., Dekker, S. L., Kamphuis, M. J., Boertien, J. M., Brunsting, J. F., Nillegoda, N. B., Bukau, B., Mayer, M. P., Kampinga, H. H. & Bergink, S., 22 May 2020, In : The Journal of Biological Chemistry. 295, 21, p. 7301-7316 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Gas-Generating, pH-Responsive Calcium Carbonate Hybrid Particles with Biomimetic Coating for Contrast-Enhanced Ultrasound Imaging

Vidallon, M. L. P., Douek, A. M., Quek, A., McLiesh, H., Kaslin, J., Tabor, R. F., Bishop, A. I. & Teo, B. M., Feb 2020, In : Particle and Particle Systems Characterization. 37, 2, 8 p., 1900471.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Growth Factor Engineering Strategies for Regenerative Medicine Applications

Ren, X., Zhao, M., Lash, B., Martino, M. M. & Julier, Z., Jan 2020, In : Frontiers in Bioengineering and Biotechnology. 7, 9 p., 469.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Growth factors with enhanced syndecan binding generate tonic signalling and promote tissue healing

Mochizuki, M., Güç, E., Park, A. J., Julier, Z., Briquez, P. S., Kuhn, G. A., Müller, R., Swartz, M. A., Hubbell, J. A. & Martino, M. M., Apr 2020, In : Nature Biomedical Engineering. 4, 4, p. 463-475 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

If Human Brain Organoids Are the Answer to Understanding Dementia, What Are the Questions?

Ooi, L., Dottori, M., Cook, A. L., Engel, M., Gautam, V., Grubman, A., Hernández, D., King, A. E., Maksour, S., Targa Dias Anastacio, H., Balez, R., Pébay, A., Pouton, C., Valenzuela, M., White, A. & Williamson, R., 13 Apr 2020, (Accepted/In press) In : Neuroscientist. 17 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo

Estermann, M. A., Williams, S., Hirst, C. E., Roly, Z. Y., Serralbo, O., Adhikari, D., Powell, D., Major, A. T. & Smith, C. A., 7 Apr 2020, In : Cell Reports. 31, 1, 19 p., 107491.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Integrating levels of bone growth control: From stem cells to body proportions

Kagan, B. J. & Rosello-Diez, A., 20 May 2020, (Accepted/In press) In : Wiley Interdisciplinary Reviews: Developmental Biology. 20 p., e384.

Research output: Contribution to journalReview ArticleResearchpeer-review

Modelling lyssavirus infections in human stem cell-derived neural cultures

Sundaramoorthy, V., Godde, N., Farr, R. J., Green, D., Haynes, J. M., Bingham, J., O’Brien, C. M. & Dearnley, M., 25 Mar 2020, In : Viruses. 12, 4, 24 p., 359.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Neurogenesis in the inner ear: The zebrafish statoacoustic ganglion provides new neurons from a Neurod/Nestin-positive progenitor pool well into adulthood

Schwarzer, S., Asokan, N., Bludau, O., Chae, J., Kuscha, V., Kaslin, J. & Hans, S., Apr 2020, In : Development (Cambridge). 147, 7, 17 p., 176750.

Research output: Contribution to journalArticleResearchpeer-review

Proximo-distal positional information encoded by an Fgf-regulated gradient of homeodomain transcription factors in the vertebrate limb

Delgado, I., Lopez-Delgado, A. C., Rosello Diez, A., Giovinazzo, G., Cadenas, V., Fernandez-de-Manuel, L., Sanchez-Cabo, F., Anderson, M. J., Lewandoski, M. & Torres, M., 3 Jun 2020, In : Science Advances. 6, 23, 9 p., eaaz0742.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS

Li, J., Sun, Y. B. Y., Chen, W., Fan, J., Li, S., Qu, X., Chen, Q., Chen, R., Zhu, D., Zhang, J., Wu, Z., Chi, H., Crawford, S., Oorschot, V., Puelles, V. G., Kerr, P. G., Ren, Y., Nilsson, S. K., Christian, M., Tang, H. & 4 others, Chen, W., Bertram, J. F., Nikolic-Paterson, D. J. & Yu, X., 5 Feb 2020, In : EMBO Reports. 21, 2, 20 p., e48781.

Research output: Contribution to journalArticleResearchpeer-review

SOX3 promotes generation of committed spermatogonia in postnatal mouse testes

McAninch, D., Mäkelä, J-A., La, H. M., Hughes, J. N., Lovell-Badge, R., Hobbs, R. M. & Thomas, P. Q., 21 Apr 2020, In : Scientific Reports. 10, 1, 13 p., 6751.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Stem cells in skeletal muscle growth and regeneration in amniotes and teleosts: Emerging themes

Ruparelia, A. A., Ratnayake, D. & Currie, P. D., Mar 2020, In : Wiley Interdisciplinary Reviews: Developmental Biology. 9, 2, 20 p., e365.

Research output: Contribution to journalReview ArticleResearchpeer-review

Systemic treatment with human amnion epithelial cells after experimental traumatic brain injury

Kim, H. A., Semple, B. D., Dill, L. K., Pham, L., Dworkin, S., Zhang, S. R., Lim, R., Sobey, C. G. & McDonald, S. J., May 2020, In : Brain, Behavior, and Immunity. 5, 8 p., 100072.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The Age-Dependent Neural Substrates of Blindsight

Fox, D. M., Goodale, M. A. & Bourne, J. A., Apr 2020, In : Trends in Neurosciences. 43, 4, p. 242-252 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

The Neuroprotective Role of Reactive Astrocytes after Central Nervous System Injury

Boghdadi, A. G., Teo, L. & Bourne, J. A., 2 Mar 2020, In : Journal of Neurotrauma. 37, 5, p. 681-691 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Transgenesis and web resources in Quail

Serralbo, O., Salgado, D., Véron, N., Cooper, C., Dejardin, M. J., Doran, T., Gros, J. & Marcelle, C., 27 May 2020, In : eLife. 9, 16 p., e56312.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

Chew, S., Lampinen, R., Saveleva, L., Korhonen, P., Mikhailov, N., Grubman, A., Polo, J. M., Wilson, T., Komppula, M., Rönkkö, T., Gu, C., Mackay-Sim, A., Malm, T., White, A. R., Jalava, P. & Kanninen, K. M., 1 Jun 2020, In : Particle and Fibre Toxicology. 17, 1, 15 p., 18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2019

Additives migrating from 3D-printed plastic induce developmental toxicity and neuro-behavioural alterations in early life zebrafish (Danio rerio)

Walpitagama, M., Carve, M., Douek, A. M., Trestrail, C., Bai, Y., Kaslin, J. & Wlodkowic, D., 1 Aug 2019, In : Aquatic Toxicology. 213, 11 p., 105227.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A Hox Code Defines Spinocerebellar Neuron Subtype Regionalization

Coughlan, E., Garside, V. C., Wong, S. F. L., Liang, H., Kraus, D., Karmakar, K., Maheshwari, U., Rijli, F. M., Bourne, J. & McGlinn, E., 19 Nov 2019, In : Cell Reports. 29, 8, p. 2408-2421 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A modular millifluidic homeostatic imaging plate for imaging of larval zebrafish

Friedrich, T., Douek, A. M., Vandestadt, C., Wlodkowic, D. & Kaslin, J., 31 Jan 2019, In : Zebrafish. 16, 1, p. 37-46 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Amyloid precursor protein and amyloid precursor-like protein 2 have distinct roles in modulating myelination, demyelination, and remyelination of axons

Truong, P. H., Ciccotosto, G. D., Merson, T. D., Spoerri, L., Chuei, M. J., Ayers, M., Xing, Y. L., Emery, B. & Cappai, R., Mar 2019, In : GLIA. 67, 3, p. 525-538 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A Neuroethics Framework for the Australian Brain Initiative

Australian Brain Alliance, 6 Feb 2019, In : Neuron. 101, 3, p. 365-369 5 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access
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2 Citations (Scopus)

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation

Jiang, J-H., Bhuiyan, M. S., Shen, H-H., Cameron, D. R., Rupasinghe, T. W. T., Wu, C. M., Le Brun, A. P., Kostoulias, X., Domene, C., Fulcher, A. J., McConville, M. J., Howden, B. P., Lieschke, G. J. & Peleg, A. Y., 26 Feb 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3722-3727 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation

Grubman, A., Chew, G., Ouyang, J. F., Sun, G., Choo, X. Y., McLean, C., Simmons, R. K., Buckberry, S., Vargas-Landin, D. B., Poppe, D., Pflueger, J., Lister, R., Rackham, O. J. L., Petretto, E. & Polo, J. M., Dec 2019, In : Nature Neuroscience. 22, 12, p. 2087-2097 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Automated Counterflow Centrifugal System for Small-Scale Cell Processing

Li, A., Wilson, S., Fitzpatrick, I., Barabadi, M., Chan, S. T., Krause, M., Kusuma, G. D., James, D. & Lim, R., 12 Dec 2019, In : Journal of Visualized Experiments. 2019, 154, 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cell-based therapies for stroke: Are we there yet?

Krause, M., Phan, T. G., Ma, H., Sobey, C. G. & Lim, R., 1 Jan 2019, In : Frontiers in Neurology. 10, JUN, 13 p., 656.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Cellular rescue in a zebrafish model of congenital muscular dystrophy type 1A

Hall, T., Wood, A., Ehrlich, O. V., Li, M., Sonntag, C., Cole, N. J., Huttner, I. G., Sztal, T. & Currie, P., 1 Dec 2019, In : npj Regenerative Medicine. 4, 1, 13 p., 21.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Class-Switch Recombination Occurs Infrequently in Germinal Centers

Roco, J. A., Mesin, L., Binder, S. C., Nefzger, C., Gonzalez-Figueroa, P., Canete, P. F., Ellyard, J., Shen, Q., Robert, P. A., Cappello, J., Vohra, H., Zhang, Y., Nowosad, C. R., Schiepers, A., Corcoran, L. M., Toellner, K. M., Polo, J. M., Meyer-Hermann, M., Victora, G. D. & Vinuesa, C. G., 20 Aug 2019, In : Immunity. 51, 2, p. 337-350 14 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Combined Blockade of Smad3 and JNK Pathways Ameliorates Progressive Fibrosis in Folic Acid Nephropathy

Jiang, M., Fan, J., Qu, X., Li, S., Nilsson, S. K., Sun, Y. B. Y., Chen, Y., Yu, D., Liu, D., Liu, B-C., Tang, M., Chen, W., Ren, Y., Nikolic-Paterson, D. J., Jiang, X., Li, J. & Yu, X., 9 Aug 2019, In : Frontiers in Pharmacology. 10, 17 p., 880.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Corrigendum: Thalamocortical Afferents Innervate the Cortical Subplate much Earlier in Development in Primate than in Rodent

Alzu'bi, A., Homman-Ludiye, J., Bourne, J. A. & Clowry, G. J., 17 Dec 2019, In : Cerebral Cortex. 29, 12, p. 5316-5316 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Culturing and measuring fetal and newborn murine long bones

Uribe, V. & Rosello Diez, A., 1 Apr 2019, In : Journal of Visualized Experiments. 2019, 146, e59509.

Research output: Contribution to journalArticleOtherpeer-review

DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Legrand, J. M. D., Chan, A. L., La, H. M., Rossello, F., Anko, M-L., Fuller-Pace, F. V. & Hobbs, R., 1 Dec 2019, In : Nature Communications. 10, 1, 21 p., 2278.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

Leong, T. L., Gayevskiy, V., Steinfort, D. P., De Massy, M. R., Gonzalez-Rajal, A., Marini, K. D., Stone, E., Chin, V., Havryk, A., Plit, M., Irving, L. B., Jennings, B. R., McCloy, R. A., Jayasekara, W. S. N., Alamgeer, M., Boolell, V., Field, A., Russell, P. A., Kumar, B., Gough, D. J. & 8 others, Szczepny, A., Ganju, V., Rossello, F. J., Cain, J. E., Papenfuss, A. T., Asselin-Labat, M. L., Cowley, M. J. & Watkins, D. N., 7 Mar 2019, In : Oncogene. 38, 10, p. 1661-1675 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Detection of gene and protein expression in mouse embryos and tissue sections

McGlinn, E., Holzman, M. A. & Mansfield, J. H., 1 Jan 2019, Vertebrate Embryogenesis. Pelegri, F. J. (ed.). New York, NY: Humana Press, p. 183-218 36 p. (Methods in Molecular Biology; vol. 1920).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns

Skvortsova, K., Masle-Farquhar, E., Luu, P. L., Song, J. Z., Qu, W., Zotenko, E., Gould, C. M., Du, Q., Peters, T. J., Colino-Sanguino, Y., Pidsley, R., Nair, S. S., Khoury, A., Smith, G. C., Miosge, L. A., Reed, J. H., Kench, J. G., Rubin, M. A., Horvath, L., Bogdanovic, O. & 5 others, Lim, S. M., Polo, J. M., Goodnow, C. C., Stirzaker, C. & Clark, S. J., 11 Feb 2019, In : Cancer Cell. 35, 2, p. 297-314 18 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)