Research Output

2020

A 9-gene score for risk stratification in B-cell acute lymphoblastic leukemia

Yan, F., Wong, N. C., Powell, D. R. & Curtis, D. J., 1 Jun 2020, (Accepted/In press) In : Leukemia. 5 p.

Research output: Contribution to journalLetterResearchpeer-review

Androgens stimulate erythropoiesis through the DNA-binding activity of the androgen receptor in non-hematopoietic cells

McManus, J. F., Nguyen, N. Y. N., Davey, R. A., MacLean, H. E., Pomilio, G., McCormack, M. P., Chiu, W. S., Wei, A. H., Zajac, J. D. & Curtis, D. J., 20 Apr 2020, (Accepted/In press) In : European Journal of Haematology. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Author Correction: KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria (Scientific Reports, (2019), 9, 1, (6356), 10.1038/s41598-019-42782-x)

Hortle, E., Starrs, L., Brown, F. C., Jane, S. M., Curtis, D. J., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2020, In : Scientific Reports. 10, 1, 1 p., 2303.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Chronic thromboembolic pulmonary hypertension from synchronous idiopathic upper extremity deep vein thrombosis and pulmonary embolism

Yuen, H. L. A., Williams, T. J., McGiffin, D. & Chunilal, S., 1 Mar 2020, In : Annals of Hematology. 99, 3, p. 667-669 3 p.

Research output: Contribution to journalLetterOtherpeer-review

Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH

Moore, H. B., Gando, S., Iba, T., Kim, P. Y., Yeh, C. H., Brohi, K., Hunt, B. J., Levy, J. H., Draxler, D. F., Stanworth, S., Görlinger, K., Neal, M. D., Schreiber, M. A., Barrett, C. D., Medcalf, R. L., Moore, E. E., Mutch, N. J., Thachil, J., Urano, T., Thomas, S. & 3 others, Scărlătescu, E., Walsh, M. & for the Subcommittees on Fibrinolysis, Disseminated Intravascular Coagulation, and Perioperative and Critical Care Thrombosis and Hemostasis, 1 Mar 2020, In : Journal of Thrombosis and Haemostasis. 18, 3, p. 740-747 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Editorial: Fibrinolysis in Immunity

Kolev, K. & Medcalf, R. L., 31 Mar 2020, In : Frontiers in Immunology. 11, 2 p., 582.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance

Barbier, V., Erbani, J., Fiveash, C., Davies, J. M., Tay, J., Tallack, M. R., Lowe, J., Magnani, J. L., Pattabiraman, D. R., Perkins, A. C., Lisle, J., Rasko, J. E. J., Levesque, J. P. & Winkler, I. G., 27 Apr 2020, In : Nature Communications. 11, 1, 15 p., 2042.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Engineering of Nebulized Metal–Phenolic Capsules for Controlled Pulmonary Deposition

Ju, Y., Cortez-Jugo, C., Chen, J., Wang, T. Y., Mitchell, A. J., Tsantikos, E., Bertleff-Zieschang, N., Lin, Y. W., Song, J., Cheng, Y., Mettu, S., Rahim, M. A., Pan, S., Yun, G., Hibbs, M. L., Yeo, L. Y., Hagemeyer, C. E. & Caruso, F., 1 Mar 2020, In : Advanced Science. 7, 6, 13 p., 1902650.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Fibrinolysis and the Immune Response in Trauma

Medcalf, R. L., Keragala, C. B. & Draxler, D. F., 1 Mar 2020, In : Seminars in Thrombosis and Hemostasis. 46, 2, p. 176-182 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

1 Citation (Scopus)

Fibrinolysis and tranexamic acid: mechanistic principles

Draxler, D. F. & Medcalf, R. L., 1 Apr 2020, In : ANZ Journal of Surgery. 90, 4, p. 410-411 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
1 Citation (Scopus)

From reads to insight: a hitchhiker's guide to ATAC-seq data analysis

Yan, F., Powell, D. R., Curtis, D. J. & Wong, N. C., 3 Feb 2020, In : Genome Biology. 21, 1, 16 p., 22.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Global coagulation assays in transgender women on oral and transdermal estradiol therapy

Lim, H. Y., Leemaqz, S. Y., Torkamani, N., Grossmann, M., Zajac, J. D., Nandurkar, H., Ho, P. & Cheung, A. S., 1 Jul 2020, In : The Journal of Clinical Endocrinology and Metabolism. 105, 7, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Hhex regulates murine lymphoid progenitor survival independently of Stat5 and Cdkn2a

Jackson, J. T., O'Donnell, K., Light, A., Goh, W., Huntington, N. D., Tarlinton, D. M. & McCormack, M. P., 23 Feb 2020, (Accepted/In press) In : European Journal of Immunology. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Patient-reported outcome measures in multiple myeloma: Real-time reporting to improve care (My-PROMPT) - a pilot randomized controlled trial

Moore, E. M., King, T. A., Wood, E. M., Ruseckaite, R., Klarica, D., Spencer, A., Ho, P. J., Quach, H., Prince, M. & McQuilten, Z. K., Jul 2020, In : American Journal of Hematology. 95, 7, p. E178-E181 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access
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Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus

Murthi, P. & Vaillancourt, C., 1 Feb 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 2, 8 p., 165391.

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)

Plasma levels of the soluble form of the FcγRIIa receptor vary with receptor polymorphisms and are elevated in rheumatoid arthritis

Qiao, J., Dunne, E., Wines, B., Kenny, D., McCarthy, G. M., Hogarth, P. M., Xu, K., Andrews, R. K. & Gardiner, E. E., 1 Apr 2020, In : Platelets. 31, 3, p. 392-398 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Risk stratification of acute pulmonary embolism and determining the effect on chronic cardiopulmonary complications: The REACH Study

Stevens, H., Fang, W., Clements, W., Bloom, J., McFadyen, J. & Tran, H., 14 Feb 2020, In : TH Open. 4, 1, p. e45-e50 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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STAT3-driven hematopoiesis and lymphopoiesis abnormalities are dependent on serine phosphorylation

Balic, J. J., White, C. L., Dawson, R., Gough, D., McCormack, M. P. & Jenkins, B. J., Jun 2020, In : Cytokine. 130, 6 p., 155059.

Research output: Contribution to journalArticleResearchpeer-review

The Complexity of Trauma-Induced Coagulopathy

Moore, H. B., Walsh, M., Kwaan, H. C. & Medcalf, R. L., 1 Mar 2020, In : Seminars in Thrombosis and Hemostasis. 46, 2, p. 114-115 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

2019

A comparison of global coagulation assays between normal controls and patients with thrombocytopenia

Lim, H. Y., Leung, P., Manitta, V., Nandurkar, H. & Ho, P., 1 Apr 2019, In : International Journal of Laboratory Hematology. 41, 2, p. 184-191 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A comparison of the efficacy of immunomodulatory-free regimens in relapsed or refractory multiple myeloma: a network meta-analysis

Weisel, K., Sonneveld, P., Spencer, A., Beksac, M., Rizzo, M., Xu, Y., Fahrbach, K., Gaudig, M., Slavcev, M., Dearden, L. & Lam, A., 1 Jan 2019, In : Leukemia and Lymphoma. 60, 19, p. 151–162 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, M., Draxler, D. F., Ho, H., McCutcheon, F., Galle, A., Au, A. E., Larsson, P., Gregory, J., Alderuccio, F., Sashindranath, M. & Medcalf, R. L., 29 Oct 2019, In : Cell Reports. 29, 5, p. 1178-1191.e6 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood

Szydzik, C., Brazilek, R. J., Akbaridoust, F., De Silva, C., Moon, M., Marusic, I., Ooi, A. S. H., Nandurkar, H. H., Hamilton, J. R., Mitchell, A. & Nesbitt, W. S., 20 Aug 2019, In : Analytical Chemistry. 91, 16, p. 10830-10839 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events

Clark, J. C., Kavanagh, D. M., Watson, S., Pike, J. A., Andrews, R. K., Gardiner, E. E., Poulter, N. S., Hill, S. J. & Watson, S. P., 1 Jul 2019, In : Thrombosis and Haemostasis. 119, 7, p. 1124-1137 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Antiphospholipid syndrome: a clinical review

Mezhov, V., Segan, J. D., Tran, H. & Cicuttini, F. M., Aug 2019, In : The Medical Journal of Australia. 211, 4, p. 184-188 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Applications of nanotechnology in the diagnosis and therapy of stroke

Landowski, L. M., Niego, B., Sutherland, B. A., Hagemeyer, C. & Howells, D. W., 28 Jun 2019, (Accepted/In press) In : Seminars in Thrombosis and Hemostasis. 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

A review of global coagulation assays — Is there a role in thrombosis risk prediction?

Lim, H. Y., O'Malley, C., Donnan, G., Nandurkar, H. & Ho, P., 1 Jul 2019, In : Thrombosis Research. 179, p. 45-55 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors (Scientific Reports, (2018), 8, 1, (12457), 10.1038/s41598-018-29865-x)

Cheung Tung Shing, K. S., Broughton, S. E., Nero, T. L., Gillinder, K., Ilsley, M. D., Ramshaw, H., Lopez, A. F., Griffin, M. D. W., Parker, M. W., Perkins, A. C. & Dhagat, U., 1 Dec 2019, In : Scientific Reports. 9, 1, 3 p., 7851.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Autologous platelet-rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

Weller, C. D., Gardiner, E. E., Arthur, J. F., Southey, M. & Andrews, R. K., Jun 2019, In : International Wound Journal. 16, 3, p. 788-792 5 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Srivastava, R., Cao, Z., Nedeva, C., Naim, S., Bachmann, D., Rabachini, T., Gangoda, L., Shahi, S., Glab, J., Menassa, J., Osellame, L., Nelson, T., Fernandez-Marrero, Y., Brown, F., Wei, A., Ke, F., O'Reilly, L., Doerflinger, M., Allison, C., Kueh, A. & 5 others, Ramsay, R., Smith, B. J., Mathivanan, S., Kaufmann, T. & Puthalakath, H., 30 Jul 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 31, p. 15469-15474 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Blinatumomab versus chemotherapy in first salvage or in later salvage for B-cell precursor acute lymphoblastic leukemia

Dombret, H., Topp, M. S., Schuh, A. C., Wei, A. H., Durrant, S., Bacon, C. L., Tran, Q., Zimmerman, Z. & Kantarjian, H., 29 Jul 2019, In : Leukemia and Lymphoma. 60, 9, p. 2214-2222 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Carbohydrates@MOFs

Astria, E., Thonhofer, M., Ricco, R., Liang, W., Chemelli, A., Tarzia, A., Alt, K., Hagemeyer, C. E., Rattenberger, J., Schroettner, H., Wrodnigg, T., Amenitsch, H., Huang, D. M., Doonan, C. J. & Falcaro, P., 1 Jun 2019, In : Materials Horizons. 6, 5, p. 969-977 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Clinicopathological aspects of therapy-related acute myeloid leukemia and myelodysplastic syndrome

Chua, C. C., Fleming, S. & Wei, A. H., 1 Mar 2019, In : Best Practice & Research: Clinical Haematology. 32, 1, p. 3-12 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)

Combining BH3-Mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia

Moujalled, D. M., Pomilio, G., Ghiurau, C., Ivey, A., Salmon, J., Rijal, S., Macraild, S., Zhang, L., Teh, T. C., Tiong, I. S., Lan, P., Chanrion, M., Claperon, A., Rocchetti, F., Zichi, A., Kraus-Berthier, L., Wang, Y., Halilovic, E., Morris, E., Colland, F. & 7 others, Segal, D., Huang, D., Roberts, A. W., Maragno, A. L., Lessene, G., Geneste, O. & Wei, A. H., 1 Apr 2019, In : Leukemia. 33, a, p. 905-917 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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29 Citations (Scopus)

Correction: High expression of HMGA2 independently predicts poor clinical outcomes in acute myeloid leukemia (Blood Cancer Journal, (2018), 8, 8, (68), 10.1038/s41408-018-0103-6)

Marquis, M., Beaubois, C., Lavallée, V. P., Abrahamowicz, M., Danieli, C., Lemieux, S., Ahmad, I., Wei, A., Ting, S. B., Fleming, S., Schwarer, A., Grimwade, D., Grey, W., Hills, R. K., Vyas, P., Russell, N., Sauvageau, G. & Hébert, J., 1 Mar 2019, In : Blood Cancer Journal. 9, 3, 1 p., 28.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

Ilsley, M. D., Huang, S., Magor, G. W., Landsberg, M. J., Gillinder, K. R. & Perkins, A. C., 24 May 2019, In : BMC Genomics. 20, 1, 12 p., 417.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Development of a novel peptide tracer for detection of cardiac fibrosis and atrial fibrillation using mouse models of cardiomyopathies

Niego, B., Alt, K., Noor, A., How, O. J., Du, X-J., Donnelly, P. S., McMullen, J. & Hagemeyer, C., 9 Jul 2019.

Research output: Contribution to conferenceAbstract

DNA-repair gene mutations are highly prevalent in circulating tumour dna from multiple myeloma patients

Mithraprabhu, S., Hocking, J., Ramachandran, M., Choi, K., Klarica, D., Khong, T., Reynolds, J. & Spencer, A., 29 Jun 2019, In : Cancers. 11, 7, 14 p., 917.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Engineering Antibodies with C-Terminal Sortase-Mediated Modification for Targeted Nanomedicine

Hashad, R. A., Lange, J. L., Tan, N. C. W., Alt, K. & Hagemeyer, C. E., 2019, Bioconjugation : Methods in Molecular Biology. Massa, S. & Devoogdt, N. (eds.). New York, NY: Humana Press, p. 67-80 14 p. (Methods in Molecular Biology; vol. 2033).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Epigenetic treatment-mediated modulation of PD-L1 predicts potential therapy resistance over response markers in myeloid malignancies: A molecular mechanism involving effectors of PD-L1 reverse signaling

Liu, H., Hu, Y., Rimoldi, R., Von Hagt, C., Khong, E. W. C., Lee, N., Flemming, S., Spencer, A. & Dear, A. E., Feb 2019, In : Oncology Letters. 17, 2, p. 2543-2550 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome

Rai, A., Greening, D. W., Chen, M., Xu, R., Ji, H. & Simpson, R. J., Apr 2019, In : Proteomics. 19, 8, 20 p., 1800148.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Fibrinolysis Shutdown in Trauma: Historical Review and Clinical Implications

Moore, H. B., Moore, E. E., Neal, M. D., Sheppard, F. R., Kornblith, L. Z., Draxler, D. F., Walsh, M., Medcalf, R. L., Cohen, M. J., Cotton, B. A., Thomas, S. G., Leeper, C. M., Gaines, B. A. & Sauaia, A., 1 Sep 2019, In : Anesthesia and Analgesia. 129, 3, p. 762-773 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

10 Citations (Scopus)

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Genetic Variants Within the Erythroid Transcription Factor, KLF1, and Reduction of the Expression of Lutheran and Other Blood Group Antigens: Review of the In(Lu)Phenotype

Fraser, N. S., Knauth, C. M., Moussa, A., Dean, M. M., Hyland, C. A., Perkins, A. C., Flower, R. L. & Schoeman, E. M., 1 Apr 2019, In : Transfusion Medicine Reviews. 33, 2, p. 111-117 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V. & 28 others, Basso, G., Locatelli, F., Enemark, E. J., Kham, S. K. Y., Yeoh, A. E. J., Ma, X., Zhou, X., Sioson, E., Rusch, M., Ries, R. E., Stieglitz, E., Hunger, S. P., Wei, A. H., To, L. B., Lewis, I. D., D’Andrea, R. J., Kile, B. T., Brown, A. L., Scott, H. S., Hahn, C. N., Marlton, P., Pei, D., Cheng, C., Loh, M. L., Ebert, B. L., Meshinchi, S., Haferlach, T. & Mullighan, C. G., Apr 2019, In : Nature Genetics. 51, 4, p. 694-704 11 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Global coagulation assays in patients with multiple myeloma and monoclonal gammopathy of unknown significance

Lim, H. Y., Brook, R., Krishnamoorthi, B., Tacey, M., Leung, T., Donnan, G., Nandurkar, H. & Ho, P., 1 Nov 2019, In : Thrombosis Research. 183, p. 45-48 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

Ku, M., MacKinnon, R. N., Wall, M., Narayan, N., Walkley, C., Cheng, H. C., Campbell, L. J., Purton, L. E. & Nandurkar, H., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 7050.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Hepatitis B management during immunosuppression for haematological and solid organ malignancies: an Australian consensus statement

Doyle, J., Raggatt, M., Slavin, M., McLachlan, S. A., Strasser, S. I., Sasadeusz, J. J., Howell, J., Hajkowicz, K., Nandurkar, H., Johnston, A., Bak, N. & Thompson, A. J., 3 Jun 2019, In : The Medical Journal of Australia. 210, 10, p. 462-468 7 p.

Research output: Contribution to journalArticleOtherpeer-review

2 Citations (Scopus)

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia

McKenzie, M. D., Ghisi, M., Oxley, E. P., Ngo, S., Cimmino, L., Esnault, C., Liu, R., Salmon, J. M., Bell, C. C., Ahmed, N., Erlichster, M., Witkowski, M. T., Liu, G. J., Chopin, M., Dakic, A., Simankowicz, E., Pomilio, G., Vu, T., Krsmanovic, P., Su, S. & 21 others, Tian, L., Baldwin, T. M., Zalcenstein, D. A., DiRago, L., Wang, S., Metcalf, D., Johnstone, R. W., Croker, B. A., Lancaster, G. I., Murphy, A. J., Naik, S. H., Nutt, S. L., Pospisil, V., Schroeder, T., Wall, M., Dawson, M. A., Wei, A. H., de Thé, H., Ritchie, M. E., Zuber, J. & Dickins, R. A., 1 Aug 2019, In : Cell Stem Cell. 25, 2, p. 258-272.e9 24 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria

Hortle, E., Starrs, L., Brown, F. C., Jane, S. M., Curtis, D. J., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 6356.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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