Research Output 1988 2019

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Abstract
2018

KRAS-mutated myeloma cells’ adaptation to glutamine-deprived conditions is linked to autophagy and macropinocytosis

Masoumi Moghaddam, S., Carmichael, I. & Spencer, A., Oct 2018. 1 p.

Research output: Contribution to conferenceAbstractOther

Molecular Patterns of Response and Outcome in the Chemotherapy and Venetoclax in Elderly AML Trial (CAVEAT) study. Blood 2018 132:333

Wei, A., Chua, C. C., Tiong, I. S., Fong, C. Y., Ting, S. B. N., Macraild, S., Salmon, J. M., Ivey, A., Nguyen, J., Yuen, F., Fleming, S. A., Bohlander, S., Reynolds, J. & Roberts, A. W., Dec 2018.

Research output: Contribution to conferenceAbstractOtherpeer-review

Open Access

Resistance to Nutrient Deprivation Via Metabolic Re-Programming As Mechanism of 'Metastasis' Promotion in Multiple Myeloma

Savvidou, I., Khong, T. T. F., Spencer, A., Chen, M., Kalff, A., Masoumi Moghaddam, S., Chandrasekara, S. & Brown, A., Dec 2018.

Research output: Contribution to conferenceAbstractOtherpeer-review

Vascular E-Selectin Acts As a Gatekeeper Inducing Commitment and Loss of Self-Renewal in HSC Transmigrating through the Marrow Vasculature

Winkler, I. G., Barbier, V., Lowe, J., Tay, J., Magnani, J. L., Marlton, P., Mills, A., Perkins, A. C., Fiveash, C. E., Erbani, J. M. & Levesque, J. P., 28 Nov 2018, p. 4552. 1 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Open Access
2017

Restoring Cardiac Function After Myocardial Infarction by Targeting CD39 to Activated Platelets.

Ziegler, M., Hohmann, J., Searle, A., Abraham, M., Nandurkar, H. H., Wang, X. & Peter, K., 2017. 1 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

2016

Evaluation of thromboelastography (teg) in patients with myeloproliferative neoplasm: platelet count> 600 (x109/L) associated with prothrombotic parameters

Smith, C., Hayes, L., Grigg, A., Nandurkar, H. & Ho, P., 2016. 1 p.

Research output: Contribution to conferenceAbstractOther

Evaluation of thromboelastography (teg) in patients with myeloproliferative neoplasm (mpn): platelet count> 600 associated with prothrombotic parameters.

Ng, C., Smith, C., Hayes, L., Grigg, L., Nandurkar, H. H. & Ho, P., 2016, p. S14.

Research output: Contribution to conferenceAbstractOtherpeer-review

2015

Global Coagulation Assays in the Normal Population: Female Gender, Older Age and East Asian Ethnicity Associated with Prothrombotic Parameters.

Ho, P., Lim, H. Y., Ng, C., Smith, C. L., Donnan, G. & Nandurkar, H. H., 2015, p. 4678.

Research output: Contribution to conferenceAbstractOtherpeer-review

Grp78 injection ameliorates haemolytic uraemic syndrome (hus) phenotype in a suburb toxin induced mouse model.

Kamel, S., Freddi, S., Selan, C., Samudra, A. N., Sharma, A., Nandurkar, H. H. & Cowan, P., 2015, p. 75-76.

Research output: Contribution to conferenceAbstractOtherpeer-review

Overcoming quiescence by targeting p21 (Cdkn1a) sensitizes pre-leukemic stem cells to chemotherapy

Tremblay, C., Saw, J. M. Y., Chiu, S. K. & Curtis, D. J., 1 Sep 2015, p. S45. 1 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

TOP2A knockdown resensitizes carfilzomib-resistant Hmcls to carfilzomib

Reale, A., Khong, T. T., Mithraprabhu, S., Savvidou, I., Ramachandran, M. & Spencer, A., Dec 2015, p. 4215. 1 p.

Research output: Contribution to conferenceAbstractOther

ZEB2 drives immature t-cell lymphoblastic leukemia development via enhanced tumor initiating potential and increased IL-7 receptor signaling

Haigh, J. J. & Goossens, S., 2015, p. S106.

Research output: Contribution to conferenceAbstractOtherpeer-review

Zeb2 loss in adult mice results in a myeloproliferative disorder and is associated with altered JAK/STAT signaling pathway

Li, J., Riedt, T., Goossens, S., Guetgemann, I., Huylebroeck, D., Haigh, J., Brossart, P. & Janzen, V., Oct 2015, p. 228. 1 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Open Access
2014

Identification and Analysis of Oncogenic Pathways in Deletion 20q Acute Myeloid Leukaemia.

Ku, M., Narayan, N., MacKinnon, R. N., Wall, M., Walkley, C., Purton, L. E., Cheng, H-C., Campbell, L. J. & Nandurkar, H. H., 2014, p. 5195.

Research output: Contribution to conferenceAbstractOtherpeer-review

2013

Identification and Analysis of Oncogenic Pathways in Deletion 20q Acute Myeloid Leukaemia. American Society of Hematology

Ku, M., Narayan, N., Wall, M., MacKinnon, R. N., Campbell, L. J. & Nandurkar, H. H., 2013, p. 1324.

Research output: Contribution to conferenceAbstractOtherpeer-review

The 78 kda glucose response protein (grp78) interacts with Atp to inhibit a modified prothrombin time.

Kamel, S., Sharma, A., Zhang, X. M., Selan, C., Samudra, A. N., Salavaris, E., Coia, G., Adams, T., Cowan, P. & Nandurkar, H. H., 2013, p. 832.

Research output: Contribution to conferenceAbstractOtherpeer-review

2012

Recombinant human erythropoietin and darbepoietin alpha exerts differential effects on non-erythroid haemopoietic cells and bone marrow microenvironment.

Dewamitta, S., Lim, H., Singbrant, S., Russell, M., Mullally, A., Ebert, B., Nandurkar, H. H. & Walkey, C., 2012, p. 97-98. 2 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

2011

Cd39 over expression protects in a murine model of antiphospholipid antibody-induced miscarriages. Journal of Thrombosis and Haemostasis.

Nandurkar, H. H., Samudra, A. N., Sharma, A., Zhang, X. M., Selan, C., Dwyer, K. & Cowan, P., 2011, p. 291.

Research output: Contribution to conferenceAbstractOtherpeer-review

The 78 kda glucose response protein (GRP78) is recruited to the surface of endothelium by interacting with thrombomodulin and it demonstrates antithrombotic activity.

Sharma, A. R., Zhang, X. M., Selan, C., Samudra, A. N., Murray-Segal, L. J., Salvaris, E. J., Michell, B., Kemp, B., Conway, E. D., YUAN, Y., Cowan, P. & Nandurkar, H. H., 2011, p. 775.

Research output: Contribution to conferenceAbstractOtherpeer-review

2010

The Symptom Burden of Patients with Haematological Malignancy: A Cross-sectional Observational Study

Manitta, V., Philip, J., Nandurkar, H. H. & Cole-Sinclair, M., 2010, p. 136.

Research output: Contribution to conferenceAbstractOtherpeer-review

2009

Development of rsolcd39-psgl as a novel therapeutic with anti-thrombotic and anti-inflammatory effects.

Dezfouli, S., Zhang, X., Crikis, S., Dwyer, K., Selan, C., Robson, S., Cowan, P. & Nandurkar, H. H., 2009, p. 87.

Research output: Contribution to conferenceAbstractOtherpeer-review

Numerical Study of Shear - Induced Thrombus formation over Aterial Stent Struts

Bark Jr., D. & Erdman, A. (ed.), 2009, p. 027525 - 027525. 1 p.

Research output: Contribution to conferenceAbstractOther

Pepsin, a measure of pulmonary microaspiration in COPD and bronchiectasis

Lee, A., Herbert, R. (ed.), Button, B., Denehy, L., Roberts, S., Bamford, T. L., Mifsud, N. A., Mu, F-T., Stirling, R. G. & Wilson, J. W., 2009, p. 13 - 13. 1 p.

Research output: Contribution to conferenceAbstractOther

The lectin-like domain of thrombomodulin and Grp78 complex exhibits novel anti-thrombotic properties.

Sharma, A., Zhang, X., Samudra, A. N., Dezfouli, S., Selan, C., Mitchell, B., Kemp, B., Cowan, P. & Nandurkar, H. H., 2009, p. 142.

Research output: Contribution to conferenceAbstractOtherpeer-review

Thrombomodulin over-expression prevent venous thrombosis and prolongs cardiac xenograft survival.

Dezfouli, S., Zhang, X., Crikis, S., Dwyer, K., Selan, C., Robson, S., Cowan, P. & Nandurkar, H. H., 2009, p. 87.

Research output: Contribution to conferenceAbstractOtherpeer-review

2008

A New Mouse Model Of Diabetic Nephropathy.

Mysore, T., Dwyer, K., Nandurkar, H. H., d'Apice, A. J. F. F. & Cowan, P., 2008, p. A139.

Research output: Contribution to conferenceAbstractOtherpeer-review

Forces on an adhering cell

Denier, J. (ed.), Berry, J. D., Finn, M. (ed.), Thompson, M. C., Mattner, T. (ed.), Carberry, J. J. & Jackson, S., 2008, p. 11690 (article) - 11691. 2 p.

Research output: Contribution to conferenceAbstractOther

2007

Anti-platelet therapy with clopidogrel or dipyridamole has no significant effect on Dss-induced murine colitis.

Lust, M., Moore, G. T., Brown, S. J., Bell, S. J., Connell, W. R., Elliott, P. R., Slavin, J. L., Nandurkar, H. H., Cowan, P., Desmond, P. V. & D'Apice, A. J. F., 2007, p. A296.

Research output: Contribution to conferenceAbstractOtherpeer-review

Doxycycline-regulated expression of Vegf-a and Angiopoietin-1 transgenes in islet beta cells.

Mysore, T., D'Apice, A. J. F., Cowan, P. & Nandurkar, H. H., 2007, p. 515-516. 2 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Increased Cd39 Expression Protects Kidneys from Ischemia Reperfusion Injury Via a Reduction in Infiltrating Cd4 T Cells; Protection Is Afforded by Expression on Either Tissue or in Blood

Crikis, S., Dwyer, K., Robson, S., Murray-Segal, L. J., Pommey, S., Winterhalter, A. C., Cowan, P. & Nandurkar, H. H., 2007, p. 277.

Research output: Contribution to conferenceAbstractOtherpeer-review

Protective effects of thrombomodulin in DSS-induced murine colitis.

Lust, M., Moore, G. T., Brown, S. J., Bell, S. J., Connell, W. R., Elliott, P. R., Stavin, J., Nandurkar, H. H., Cowan, P., Desmond, P. V. & D'apice, T., 2007, p. A396.

Research output: Contribution to conferenceAbstractOtherpeer-review

Transgenic expression of human Cd39 protects kidneys from ischaemia reperfusion injury through the generation of adenosine and inhibition of Cd4+ t cells.

Crikis, S., Dwyer, K., Robson, S., Murray-Segal, L. J., Pommey, S., Winterhalter, A. C., Cowan, P., Nandurkar, H. H. & D'Apice, A. J. F., 2007, p. 417.

Research output: Contribution to conferenceAbstractOtherpeer-review

2006

Increased Cd39 Expression Protects Kidneys From Ischemia Reperfusion Injury

Crikis, S., Karen, D. M., Robson, S., Murray-Segal, L. J., Cowan, P. J., Nandurkar, H. H. & D'Apice, A. J. F., 2006, p. 1041-1042. 2 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Increased Tissue Cd39 Expression Protects Kidneys From Ischemia Reperfusion Injury Independently Of Cellular Blood Constituents And Reduces Apoptosis Via The A20 Pathway.

Crikis, S., Dwyer, K. M., Robson, S., Murray-Segal, L. J., Pommey, S., Cowan, P. J., Nandurkar, H. H. & D'Apice, A. J. F., 2006, p. A1.

Research output: Contribution to conferenceAbstractOtherpeer-review

The effects of thrombomodulin on experimental colitis

Lust, M., Moore, G. T. C., Brown, S. J., Bell, S. J., Connell, W. R., Elliott, P. R., Slavin, J. L., Nandurkar, H. H., Cowan, P. J., Desmond, P. V. & D'Apice, A. J. F., 2006, p. A280.

Research output: Contribution to conferenceAbstractOtherpeer-review

The effects of tissue factor pathway inhibitor on experimental colitis

Lust, M., Moore, G. T. C., Brown, S. J., Bell, S. J., Connell, W. R., Elliott, P. R., Slavin, J. L., Nandurkar, H. H., Cowan, P. J., Desmond, P. V. & D'Apice, A. J. F., 2006, p. A281.

Research output: Contribution to conferenceAbstractOtherpeer-review

Transgenic Expression Of Cd39 Or Thrombomodulin Confers Protection In A Murine Cardiac Xenotransplantation Model.

Crikis, S., Dwyer, K., Robson, S., Nandurkar, H. H. & Cowan, P., 2006, p. A24.

Research output: Contribution to conferenceAbstractOtherpeer-review

2005

Cd39 a nuclcotide triphosphate diphosphorylase worsens Colitis in the Huft1 transgenic mouse.

Moore, G. T. C., Brown, S. J., Miller, A. M., Dwyer, K. M., Bell, S. J., Elliott, P. T., Connell, W. R., Nandurkar, H. H., Cowan, P. J. & D'Apice, A. J. F., 2005, p. A202.

Research output: Contribution to conferenceAbstractOtherpeer-review

Demonstration of hypercoagulability in the hfut1 transgenic mouse model of colitis.

Moore, G. T., Lust, M., Brown, M. J., Bell, S. J., Elliott, P. R., Connell, W. R., Nandurkar, H. H., Cowan, P. J., Desmond, P. V. & d'Apice, A. J. F. F., 2005, p. A22.

Research output: Contribution to conferenceAbstractOtherpeer-review

Mammalian genetic models with minimal or complex phenotypes-Targeted Disruption of SPI3/Serpinb6 Does Not Result in Developmental or Growth Defects, Leukocyte Dysfunction, or Susceptibility to.

Scarff, K. L., Ung, K. S., Nandurkar, H. H., Crack, P. J., Bird, C. H. & Bird, P. I., 2005, p. 4075.

Research output: Contribution to conferenceAbstractOtherpeer-review

Transgenic Cd39 Expression Protects Against Renal Ischemia Reperfusion Injury.

Crikis, S., Dwyer, K., Murray-Segal, L. J., Fisicaro, N., Robson, S., Cowan, P., Nandurkar, H. H. & d'Apice, A. J. F. F., 2005, p. A379.

Research output: Contribution to conferenceAbstractOtherpeer-review

2004

Phenotypic Evaluation Of Mice Transgenic For Human Thrombomodulin And Tfpi.

Crikis, S., Dwyer, K., Robson, S., Nandurkar, H. H., Murray-Segal, L. J., Fisicaro, N., Cowan, P. & D'Apice, A. J. F., 2004, p. 575.

Research output: Contribution to conferenceAbstractOtherpeer-review

2003

FHL3 is an actin bundling protein that regulates alpha actinin mediated actin bundling.

Coghill, I. D., Brown, S., Cottle, D. L., McGrath, M. J., Robinson, P. A. & Nandurkar, H. H., 2003, p. 24139-24152. 13 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Hemostasis, Thrombosis, and Vascular Biology-Ship-2 forms a tetrameric complex with filamin, actin, and GPIb-IX-V-localization of SHIP-2 to the activated platelet actin cytoskeleton

Dyson, J. M., Munday, A. D., Kong, A. M., Huysmans, R. D., Matzaris, M., Layton, M. J., Berndt, M. C., Nandurkar, H. H. & Mitchell, C. A., 2003, p. 575.

Research output: Contribution to conferenceAbstractOtherpeer-review