Research Output 1988 2019

2014

RE: An update of consensus guidelines for warfarin reversal

Tran, H. A., Chunilal, S. & Tran, H., 2014, In : Medical Journal of Australia. 200, 2, p. 82 - 82 1 p.

Research output: Contribution to journalLetterOther

Safe and effective use of outpatient non-myeloablative allogeneic stem cell transplantation for myeloma

Campbell, P., Walker, P. A., Avery, S., Curtis, D. J., Schwarer, A., Wei, A., Kalff, A., Muirhead, J. L. & Spencer, A., 2014, In : Blood Cancer Journal. 4, 5, p. e213 - e213 3 p.

Research output: Contribution to journalLetterOther

SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells

Gerby, B., Tremblay, C., Tremblay, M., Rojas-Sutterlin, S., Herblot, S., Hebert, J., Sauvageau, G., Lemieux, S., Lecuyer, E., Veiga, D. F. T. & Trang, H., 2014, In : PLoS Genetics. 10, 12, 19 p., e1004768.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data

Palumbo, A., Bringhen, S., Kumar, S. K., Lupparelli, G., Usmani, S. Z., Waage, A., Larocca, A. T., Van Der Holt, B. R., Musto, P., Offidani, M., Petrucci, M. T., Evangelista, A., Zweegman, S., Nooka, A. K., Spencer, A., Dimopoulos, M. A., Hajek, R., Cavo, M. M., Richardson, P. G., Lonial, S. & 6 othersCiccone, G., Boccadoro, M., Anderson, K. C., Barlogie, B. M., Sonneveld, P. & McCarthy, P. L., 2014, In : Lancet Oncology. 15, 3, p. 333 - 342 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia

Cummins, K. D., Jane, S. M., Nikovic, S., Bazargan, A., Filshie, R. J. A., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, P. D., D'Rozario, J., Black, J., Bavishi, K. & Wei, A., 2014, In : Blood Cancer Journal. 4, 8, e237.

Research output: Contribution to journalLetterOtherpeer-review

Open Access
File

Species-specific regulation of t-PA and PAI-1 gene expression in human and rat astrocytes

Tjarnlund Wolf, A., Hultman, K., Blomstrand, F., Nilsson, M., Medcalf, R. L. & Jern, C., 2014, In : Gene Regulation and Systems Biology. 2014, 8, p. 113 - 118 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Structure and function of platelet receptors initiating blood clotting

Gardiner, E. E. & Andrews, R. K., 2014, In : Advances in Experimental Medicine and Biology. 844, p. 263 - 275 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeting GPVI as a novel antithrombotic strategy

Andrews, R. K., Arthur, J. F. & Gardiner, E. E., 2014, In : Journal of Blood Medicine. 2014, 5, p. 59 - 68 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Techniques towards understanding shear dependent thrombus formation

Pinar, I., Arthur, J., Andrews, R., Gardiner, E., Ryan, K. & Carberry, J., 2014, Proceedings of the 19th Australasian Fluid Mechanics Conference (AFMC). Chowdhury, H. & Alam, F. (eds.). Melbourne Vic Australia: RMIT University, p. 1 - 4 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Thalidomide and prednisolone versus prednisolone alone as consolidation therapy after autologous stem-cell transplantation in patients with newly diagnosed multiple myeloma: Final analysis of the ALLG MM6 multicentre, open-label, randomised phase 3 study

Kalff, A., Kennedy, N., Smiley, A., Miles Prince, H., Roberts, A. W., Bradstock, K., de Abreu Lourenço, R., Frampton, C. & Spencer, A., 2014, In : The Lancet Haematology. 1, 3, p. e112-e119 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia

Tremblay, C. & Curtis, D. J., 2014, In : Current Opinion in Hematology. 21, 4, p. 320 - 325 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice

Lancaster, G. I., Kraakman, M. J., Kammoun, H. L., Langley, K. G., Estevez, E., Banerjee, A., Grumont, R. J., Febbraio, M. A. & Gerondakis, S. D., 2014, In : PLoS ONE. 9, 11, 8 p., e111524.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression

Huard, C. C., Tremblay, C., Magron, A., Levesque, G. & Carreau, M., 2014, In : Proceedings of the National Academy of Sciences. 111, 6, p. 2152 - 2157 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

Spencer, A., Yoon, S-S., Harrison, S., Morris, S. R., Smith, D. A., Brigandi, R. A., Gauvin, J. L. S., Kumar, R., Opalinska, J. B. & Chen, C., 2014, In : Blood. 124, 14, p. 2190 - 2195 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of HiDAC in AML - Author Reply

Wei, A. & Fleming, S. A., 2014, In : Internal Medicine Journal. 44, 8, p. 825 - 825 1 p.

Research output: Contribution to journalLetterOther

The successful management of dabigatran-associated critical end-organ bleeding with recombinant factor VIIa

Htun, K. T., McFadyen, J. D. & Tran, H. A., 2014, In : Annals of Hematology. 93, 10, p. 1785 - 1786 2 p.

Research output: Contribution to journalLetterOtherpeer-review

Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets

Wang, X., Palasubramaniam, J., Gkanatsas, Y., Hohmann, J. D., Westein, E., Kanojia, R., Alt, K., Huang, D., Jia, F., Ahrens, I., Medcalf, R. L., Peter, K. & Hagemeyer, C. E., 2014, In : Circulation Research. 114, 7, p. 1083 - 1093 11 p.

Research output: Contribution to journalArticleResearchpeer-review

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions

Freeman, R., Niego, B., Croucher, D. R., Pederson, L. O. & Medcalf, R. L., 2014, In : Brain Research. 1565, p. 63 - 73 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Underestimation of myelodysplastic syndrome incidence by cancer registries: results from a population-based data linkage study

McQuilten, Z., Wood, E. M., Polizzotto, M. N., Campbell, L., Wall, M., Curtis, D. J., Farrugia, H., McNeil, J. J. & Sundararajan, V., 2014, In : Cancer. 120, 11, p. 1686 - 1694 9 p.

Research output: Contribution to journalArticleResearchpeer-review

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Tatari, M. N., De Craene, B. A., Soen, B., Taminau, J., Vermassen, P., Goossens, S., Haigh, K., Cazzola, S., Lambert, J., Huylebroeck, D., Haigh, J. J. & Berx, G., 2014, In : Cellular and Molecular Life Sciences. 71, 18, p. 3599-3609 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

ADAMTS13 antibody depletion by bortezomib in thrombotic thrombocytopenic purpura

Shortt, J., Oh, D. H. & Opat, S., 2013, In : New England Journal of Medicine. 368, 1, p. 90 - 92 3 p.

Research output: Contribution to journalLetterOther

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein ibalpha

Kruss, S., Erpenbeck, L., Amschler, K., Mundinger, T. A., Boehm, H., Helms, H. J., Friede, T., Andrews, R. K., Schon, M. & Spatz, J. P., 2013, In : ACS Nano. 7, 11, p. 9984 - 9996 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green, B. D., Jabbour, A. M., Sandow, J. J., Riffkin, C. D., Masouras, D., Daunt, C. P., Salmanidis, M., Brumatti, G., Hemmings, B., Guthridge, M. A., Pearson, R. B. & Ekert, P. G., 2013, In : Cell Death and Differentiation. 20, 10, p. 1341 - 1349 9 p.

Research output: Contribution to journalArticleResearchpeer-review

AKT Isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans

Haslinger, P., Haidar, S., Sonderegger, S. E., Otten, J. V., Pollheimer, J., Whitley, G. & Knofler, M., 2013, In : Biology of Reproduction. 88, 3, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A multimode-TIRFM and microfluidic technique to examine platelet adhesion dynamics

Nesbitt, W. S., Tovar-Lopez, F. J., Westein, E., Harper, I. S. & Jackson, S., 2013, Adhesion Protein Protocols. Coutts, A. S. (ed.). USA: Humana Press, Vol. 1046. p. 39 - 58 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

An investigation on platelet transport during thrombus formation at micro-scale stenosis

Tovar-Lopez, F. J., Rosengarten, G., Nasabi, M., Sivan, V., Khoshmanesh, K., Jackson, S., Mitchell, A. & Nesbitt, W. S., 2013, In : PLoS ONE. 8, 10 (Art. ID: e74123), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Bernard-Soulier syndrome: an update

Andrews, R. K. & Berndt, M. C., 2013, In : Seminars in Thrombosis and Hemostasis. 39, 6, p. 656 - 662 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cre/loxP - Transgenics

Haenebalcke, L. & Haigh, J., 2013, Brenner's Encyclopedia of Genetics. Maloy, S. & Hughes, K. (eds.). Second ed. San Diego: Academic Press, p. 212 - 217 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Cytotoxic effects of bromelain and N-acetylcysteine on gastrointestinal cancer cell lines

Amini, A., Masoumi Moghaddam, S., Ehteda, A. & Morris, D. L., 2013.

Research output: Contribution to conferencePosterOtherpeer-review

Cytotoxic effects of bromelain and N-acetylcysteine on the gastric carcinoma cell line KATO-III

Amini, A., Ehteda, A., Masoumi Moghaddam, S. & Morris, D. L., 2013.

Research output: Contribution to conferencePosterOtherpeer-review

Cytotoxic effects of pineapple bromelain in gastrointestinal carcinoma cell lines

Amini, A., Masoumi Moghaddam, S., Ehteda, A. & Morris, D. L., 2013.

Research output: Contribution to conferencePosterOtherpeer-review

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Costa, M., Sourris, K., Lim, S. M., Yu, Q. C., Hirst, C. E., Parkington, H. C., Jameson-Jokubaitis, V. J., Dear, A. E., Liu, H. B., Micallef, S. J., Koutsis, K., Elefanty, A. G. & Stanley, E., 2013, In : Stem Cell Research. 10, 1, p. 103 - 117 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Differentiating haemostasis from thrombosis for therapeutic benefit

McFadyen, J. D. & Jackson, S., 2013, In : Thrombosis and Haemostasis. 110, 5, p. 859 - 867 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL

Sleebs, B., Kersten, W. J. A., Kulasegaram, S., Nikolakopoulos, G., Hatzis, E., Moss, R. M., Parisot, J. P., Yang, H., Czabotar, P. E., Fairlie, W. D., Lee, E. F., Adams, J. M., Chen, L., van Delft, M. F., Lowes, K. N., Wei, A., Huang, D. CS., Colman, P. M., Street, I. P., Baell, J. B. & 2 othersWatson, K. G. & Lessene, G., 2013, In : Journal of Medicinal Chemistry. 56, 13, p. 5514 - 5540 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Effectiveness of a single fixed dose of rasburicase 3 mg in the management of tumour lysis syndrome

Coutsouvelis, J., Wiseman, M., Hui, L., Poole, S., Dooley, M., Patil, S., Avery, S., Wei, A. & Spencer, A., Feb 2013, In : British Journal of Clinical Pharmacology. 75, 2, p. 565-568 4 p.

Research output: Contribution to journalLetterOtherpeer-review

Effect of the induced expression of human Sprouty protein-1 (Spry1) on SKOV-3 human ovarian cancer cells’ proliferation, migration, invasion and survival in vitro

Masoumi Moghaddam, S., Amini, A., Wei, A-Q. & Morris, D. L., 2013.

Research output: Contribution to conferencePosterOtherpeer-review

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

Haenebalcke, L., Goossens, S., Naessens, M., Kruse, N., Ghahremani, M. F., Bartunkova, S., Haigh, K., Pieters, T., Dierickx, P., Drogat, B., Nyabi, O., Wirth, D. & Haigh, J. J., 2013, In : Stem Cell Reviews. 9, 6, p. 774-785 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Endothelial VEGF sculpts cortical cytoarchitecture

Li, S., Haigh, K., Haigh, J. J. & Vasudevan, A., 2013, In : Journal of Neuroscience. 33, 37, p. 14809 - 14815 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells

Wightman, F., Lu, H. K., Solomon, A., Saleh, S. M., Harman, A. N., Cunningham, A. L., Gray, L. R., Churchill, M., Cameron, P. U., Dear, A. E. & Lewin, S. R., 2013, In : AIDS. 27, 18, p. 2853 - 2862 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

ENU mutagenesis identifies the first mouse mutants reproducing human beta-thalassemia at the genomic level

Brown, F., Scott, N., Rank, G., Collinge, J. E., Vadolas, J., Vickaryous, N., Whitelaw, N. C., Whitelaw, E., Kile, B., Jane, S. M. & Curtis, D. J., 2013, In : Blood Cells, Molecules, and Diseases. 50, 2, p. 86-92 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Exacerbation of glycoprotein VI-dependent platelet responses in a rhesus monkey model of type 1 diabetes

Arthur, J. F., Shen, Y., Chen, Y., Qiao, J. L., Ni, R., Lu, Y. R., Andrews, R. K., Gardiner, E. E. & Cheng, J., 2013, In : Journal of Diabetes Research. 2013, Art. ID: 370212, p. 1 - 9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Factor XIII assays

Opat, S., Butler, J., Malan, E., Duncan, E. M. & Tran, H. A., 2013, Haemostasis: Methods and Protocols. Monagle, P. (ed.). United States: Humana Press, Vol. 992. p. 171 - 180 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1

Huard, C. C., Tremblay, C., Helsper, K., Delisle, M-C., Schindler, D., Levesque, G. & Carreau, M., 2013, In : Blood. 121, 10, p. 1729 - 1739 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma

Smeets, M. F. M. A., Chan, A. C. Y., Dagger, S., Bradley, C., Wei, A. & Izon, D. J., 2013, In : PLoS ONE. 8, 5, 12 p., e62346.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Fludarabine, cytarabine, granulocyte-colony stimulating factor and amsacrine: an effective salvage therapy option for acute myeloid leukemia at first relapse

Fong, C. Y., Grigoriadis, G., Hocking, J., Coutsouvelis, J., Muirhead, J. L., Campbell, P., Paul, E., Walker, P. A., Avery, S., Patil, S., Spencer, A., Schwarer, A. & Wei, A., 2013, In : Leukemia and Lymphoma. 54, 2, p. 336 - 341 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Herold, M., Rohrbeck, L., Lang, M., Grumont, R. J., Gerondakis, S. D., Tai, L., Bouillet, P., Kaufmann, T. & Strasser, A., 2013, In : EMBO Reports. 14, 11, p. 992 - 998 7 p.

Research output: Contribution to journalArticleResearchpeer-review

GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations

Perugini, M., Iarossi, D. G., Kok, C. H., Cummings, N. J., Diakiw, S. M., Brown, A. L., Danner, S., Bardy, P., To, L. B., Wei, A., Lewis, I. D. & Andrea, R. J. D., 2013, In : Leukemia. 27, 7, p. 1588 - 1592 5 p.

Research output: Contribution to journalArticleResearchpeer-review

GLP-1-dependent and independent effects and molecular mechanisms of a dipeptidyl peptidase 4 inhibitor in vascular endothelial cells

Hu, Y., Liu, H. B., Simpson, R. & Dear, A. E., 2013, In : Molecular Biology Reports. 40, 3, p. 2273 - 2279 7 p.

Research output: Contribution to journalArticleResearchpeer-review

High-dose cytarabine (24g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia

Low, M., Lee, D., Coutsouvelis, J., Patil, S., Opat, S., Walker, P. A., Schwarer, A., Salem, H. H., Avery, S., Spencer, A. & Wei, A., 2013, In : Internal Medicine Journal. 43, 3, p. 294 - 297 4 p.

Research output: Contribution to journalArticleResearchpeer-review