Research Output 1984 2019

2014

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

Denecker, G., Vandamme, N., Akay, O., Koludrovic, D., Taminau, J., Lemeire, K., Gheldof, A., Craene, B. D., Van Gele, M., Brochez, L., Udupi, G. M., Rafferty, M., Balint, B., Gallagher, W. M., Ghanem, G., Huylebroeck, D., Haigh, J. J., van den Oord, J., Larue, L., Davidson, I. & 2 others, Marine, J-C. & Berx, G., 2014, In : Cell Death and Differentiation. 21, 8, p. 1250 - 1261 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Incidence of venous thromboembolism in different ethnic groups: a regional direct comparison study

Liao, S., Woulfe, T., Hyder, S. W., Merriman, E. G., Simpson, D. E. & Chunilal, S., 2014, In : Journal of Thrombosis and Haemostasis. 12, 2, p. 214 - 219 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Is plasminogen activator inhibitor type 2 really a plasminogen activator inhibitor after all?

Gardiner, E. E. & Medcalf, R. L., 2014, In : Journal of Thrombosis and Haemostasis. 12, 10, p. 1703 - 1705 3 p.

Research output: Contribution to journalArticleOther

Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia

Hawkins, E., Oliaro, J., Ramsbottom, K. M., Ting, S. B. N., Sacirbegovic, F., Harvey, M., Kinwell, T., Ghysdael, J., Johnstone, R. W., Humbert, P. O. & Russell, S. M., 2014, In : PLoS ONE. 9, 1 (Art. No.: e87376), p. 1 - 5 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice

Ghahremani, M. F., Radaelli, E., Haigh, K., Bartunkova, S., Haenebalcke, L., Marine, J-C., Goossens, S. & Haigh, J. J., 2014, In : Cell Cycle. 13, 9, p. 1501-1507 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Low-molecular-weight heparin biosimilars: Potential implications for clinical practice

Nandurkar, H. H., Chong, B. H., Salem, H. H., Gallus, A., Ferro, V. & McKinnon, R. A., 2014, In : Internal Medicine Journal. 44, 5, p. 497 - 500 4 p.

Research output: Contribution to journalArticleOtherpeer-review

Lymphomania

Andrews, R. K. & Gardiner, E. E., 2014, In : Blood. 123, 20, p. 3057 - 3058 2 p.

Research output: Contribution to journalLetterOther

Mechanisms and potential molecular markers of early response to combination epigenetic therapy in patients with myeloid malignancies

Liu, H. B., Urbanavicius, D. B., Tan, P., Spencer, A. & Dear, A. E., 2014, In : International journal of oncology. 45, 4, p. 1742 - 1748 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Molecular cloning and characterization of rhesus monkey platelet glycoprotein Ibalpha, a major ligand-binding subunit of GPIb-IX-V complex

Qiao, J. L., Shen, Y., Shi, M., Lu, Y. R., Cheng, J. & Chen, Y., 2014, In : Thrombosis Research. 133, 5, p. 817 - 825 9 p.

Research output: Contribution to journalArticleResearchpeer-review

N-Acetylcysteine for thrombotic thrombocytopenic purpura: Is a von Willebrand factor-inhibitory dose feasible in vivo?

Shortt, J., Opat, S. & Wood, E. M., 2014, In : Transfusion. 54, 9, p. 2362 - 2363 2 p.

Research output: Contribution to journalLetterOther

Neutrophil extracellular traps (NETs) and the role of platelets in infection

Andrews, R. K., Arthur, J. F. & Gardiner, E. E., 2014, In : Thrombosis and Haemostasis. 112, 4, p. 659 - 665 7 p.

Research output: Contribution to journalArticleResearchpeer-review

New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management

Tran, H. A., Joseph, J. E., Young, L., McRae, S., Curnow, J., Nandurkar, H., Wood, P. & McLintock, C. K., 2014, In : Internal Medicine Journal. 44, 6, p. 525 - 536 12 p.

Research output: Contribution to journalArticleResearchpeer-review

NF-{kappa}B control of T cell development

Gerondakis, S. D., Fulford, T., Messina, N. L. & Grumont, R. J., 2014, In : Nature Immunology. 15, 1, p. 15 - 25 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimal approach for high-risk acute promyelocytic leukemia

Iland, H. J., Seymour, J. F. & Wei, A., 2014, In : Current Opinion in Hematology. 21, 2, p. 102 - 113 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Outcomes following second allogeneic haematopoietic transplants using fludarabine-melphalan conditioning

Bilmon, I., Nivison-Smith, I., Hertzberg, M. S., Ritchie, D., Greenwood, M. J., Spencer, A., Kennedy, G. A., Bryant, A. & Moore, J., 2014, In : Bone Marrow Transplantation. 49, 6, p. 852 - 853 2 p.

Research output: Contribution to journalLetterOther

Open Access

Oxidation of an exposed methionine instigates the aggregation of glyceraldehyde-3-phosphate dehydrogenase

Samson, A. L., Knaupp, A. S., Kass, I., Kleifeld, O., Marijanovic, E. M., Hughes, V. A., Lupton, C. J., Buckle, A. M., Bottomley, S. P. & Medcalf, R. L., 2014, In : Journal of Biological Chemistry. 289, 39, p. 26922 - 26936 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasma sGPVI: Changing levels in human disease

Gardiner, E. E. & Andrews, R. K., 2014, In : Thrombosis Research. 133, 3, p. 306 - 307 2 p.

Research output: Contribution to journalLetterOther

Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis?

Niego, B. & Medcalf, R. L., 2014, In : Journal of Cerebral Blood Flow and Metabolism. 34, 8, p. 1283 - 1296 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access

Platelet receptor expression and shedding: Glycoprotein Ib-IX-V and glycoprotein VI

Gardiner, E. E. & Andrews, R. K., 2014, In : Transfusion Medicine Reviews. 28, 2, p. 56 - 60 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymorphisms and interspecies differences of the activating and inhibitory Fc{gamma}RII of Macaca nemestrina influence the binding of human IgG subclasses

Trist, H., Tan, P., Wines, B. D., Ramsland, P. A., Orlowski, E., Stubbs, J., Gardiner, E. E., Pietersz, G. A., Kent, S. J., Stratov, I., Burton, D. & Hogarth, P. M., 2014, In : Journal of Immunology. 192, 2, p. 792 - 803 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Post-thrombotic syndrome: A potential cause of venous ulcer

Arumugaswamy, A. & Tran, H. A., 2014, In : Wound Practice & Research. 22, 2, p. 85 - 90 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Primary haemostasis: newer insights

Berndt, M. C., Metharom, P. & Andrews, R. K., 2014, In : Haemophilia. 20, S4, p. 15 - 22 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Prothrombin complex concentrate safely reverses warfarin-related bleeding

Tran, H. A. & Chunilal, S., 2014, In : Evidence-Based Medicine. 19, 2, p. 75 - 75 1 p.

Research output: Contribution to journalLetterOther

Rab8a interacts directly with PI3Kgamma to modulate TLR4-driven PI3K and mTOR signalling

Luo, L., Wall, A. A., Yeo, J. C., Condon, N. D., Norwood, S. J., Schoenwaelder, S. M., Chen, K. W., Jackson, S., Jenkins, B. J., Hartland, E. L., Schroder, K., Collins, B. M., Sweet, M. J. & Stow, J. L., 2014, In : Nature Communications. 5, (Art. No.:4407), p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

RE: An update of consensus guidelines for warfarin reversal

Tran, H. A., Chunilal, S. & Tran, H., 2014, In : Medical Journal of Australia. 200, 2, p. 82 - 82 1 p.

Research output: Contribution to journalLetterOther

Safe and effective use of outpatient non-myeloablative allogeneic stem cell transplantation for myeloma

Campbell, P., Walker, P. A., Avery, S., Curtis, D. J., Schwarer, A., Wei, A., Kalff, A., Muirhead, J. L. & Spencer, A., 2014, In : Blood Cancer Journal. 4, 5, p. e213 - e213 3 p.

Research output: Contribution to journalLetterOther

SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells

Gerby, B., Tremblay, C., Tremblay, M., Rojas-Sutterlin, S., Herblot, S., Hebert, J., Sauvageau, G., Lemieux, S., Lecuyer, E., Veiga, D. F. T. & Trang, H., 2014, In : PLoS Genetics. 10, 12, 19 p., e1004768.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Second primary malignancies with lenalidomide therapy for newly diagnosed myeloma: a meta-analysis of individual patient data

Palumbo, A., Bringhen, S., Kumar, S. K., Lupparelli, G., Usmani, S. Z., Waage, A., Larocca, A. T., Van Der Holt, B. R., Musto, P., Offidani, M., Petrucci, M. T., Evangelista, A., Zweegman, S., Nooka, A. K., Spencer, A., Dimopoulos, M. A., Hajek, R., Cavo, M. M., Richardson, P. G., Lonial, S. & 6 others, Ciccone, G., Boccadoro, M., Anderson, K. C., Barlogie, B. M., Sonneveld, P. & McCarthy, P. L., 2014, In : Lancet Oncology. 15, 3, p. 333 - 342 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Sorafenib priming may augment salvage chemotherapy in relapsed and refractory FLT3-ITD-positive acute myeloid leukemia

Cummins, K. D., Jane, S. M., Nikovic, S., Bazargan, A., Filshie, R. J. A., Sutrave, G., Hertzberg, M., Scott, A., Lane, S., Yannakou, C. K., Ritchie, P. D., D'Rozario, J., Black, J., Bavishi, K. & Wei, A., 2014, In : Blood Cancer Journal. 4, 8, e237.

Research output: Contribution to journalLetterOtherpeer-review

Open Access
File

Species-specific regulation of t-PA and PAI-1 gene expression in human and rat astrocytes

Tjarnlund Wolf, A., Hultman, K., Blomstrand, F., Nilsson, M., Medcalf, R. L. & Jern, C., 2014, In : Gene Regulation and Systems Biology. 2014, 8, p. 113 - 118 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Structure and function of platelet receptors initiating blood clotting

Gardiner, E. E. & Andrews, R. K., 2014, In : Advances in Experimental Medicine and Biology. 844, p. 263 - 275 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeting GPVI as a novel antithrombotic strategy

Andrews, R. K., Arthur, J. F. & Gardiner, E. E., 2014, In : Journal of Blood Medicine. 2014, 5, p. 59 - 68 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Techniques towards understanding shear dependent thrombus formation

Pinar, I., Arthur, J., Andrews, R., Gardiner, E., Ryan, K. & Carberry, J., 2014, Proceedings of the 19th Australasian Fluid Mechanics Conference (AFMC). Chowdhury, H. & Alam, F. (eds.). Melbourne Vic Australia: RMIT University, p. 1 - 4 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Thalidomide and prednisolone versus prednisolone alone as consolidation therapy after autologous stem-cell transplantation in patients with newly diagnosed multiple myeloma: Final analysis of the ALLG MM6 multicentre, open-label, randomised phase 3 study

Kalff, A., Kennedy, N., Smiley, A., Miles Prince, H., Roberts, A. W., Bradstock, K., de Abreu Lourenço, R., Frampton, C. & Spencer, A., 2014, In : The Lancet Haematology. 1, 3, p. e112-e119 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia

Tremblay, C. & Curtis, D. J., 2014, In : Current Opinion in Hematology. 21, 4, p. 320 - 325 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice

Lancaster, G. I., Kraakman, M. J., Kammoun, H. L., Langley, K. G., Estevez, E., Banerjee, A., Grumont, R. J., Febbraio, M. A. & Gerondakis, S. D., 2014, In : PLoS ONE. 9, 11, 8 p., e111524.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

The expression of the human Sprouty protein-1 (hSpry1) inversely correlates with proliferation, migration and invasion of the SKOV-3 and 1A9 human ovarian cancer cells

Masoumi Moghaddam, S., Amini, A. & Morris, D. L., 2014.

Research output: Contribution to conferencePosterOtherpeer-review

The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression

Huard, C. C., Tremblay, C., Magron, A., Levesque, G. & Carreau, M., 2014, In : Proceedings of the National Academy of Sciences. 111, 6, p. 2152 - 2157 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

Spencer, A., Yoon, S-S., Harrison, S., Morris, S. R., Smith, D. A., Brigandi, R. A., Gauvin, J. L. S., Kumar, R., Opalinska, J. B. & Chen, C., 2014, In : Blood. 124, 14, p. 2190 - 2195 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of HiDAC in AML - Author Reply

Wei, A. & Fleming, S. A., 2014, In : Internal Medicine Journal. 44, 8, p. 825 - 825 1 p.

Research output: Contribution to journalLetterOther

The successful management of dabigatran-associated critical end-organ bleeding with recombinant factor VIIa

Htun, K. T., McFadyen, J. D. & Tran, H. A., 2014, In : Annals of Hematology. 93, 10, p. 1785 - 1786 2 p.

Research output: Contribution to journalLetterOtherpeer-review

TNFalpha stimulation desensitises a human in vitro BBB model to t-PA-mediated permeabilisation.

Niego, B., Sashindranath, M., Galle, A., Freeman, R. & Medcalf, R., 11 Dec 2014.

Research output: Contribution to conferenceAbstractOtherpeer-review

Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets

Wang, X., Palasubramaniam, J., Gkanatsas, Y., Hohmann, J. D., Westein, E., Kanojia, R., Alt, K., Huang, D., Jia, F., Ahrens, I., Medcalf, R. L., Peter, K. & Hagemeyer, C. E., 2014, In : Circulation Research. 114, 7, p. 1083 - 1093 11 p.

Research output: Contribution to journalArticleResearchpeer-review

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions

Freeman, R., Niego, B., Croucher, D. R., Pederson, L. O. & Medcalf, R. L., 2014, In : Brain Research. 1565, p. 63 - 73 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Underestimation of myelodysplastic syndrome incidence by cancer registries: results from a population-based data linkage study

McQuilten, Z., Wood, E. M., Polizzotto, M. N., Campbell, L., Wall, M., Curtis, D. J., Farrugia, H., McNeil, J. J. & Sundararajan, V., 2014, In : Cancer. 120, 11, p. 1686 - 1694 9 p.

Research output: Contribution to journalArticleResearchpeer-review

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Tatari, M. N., De Craene, B. A., Soen, B., Taminau, J., Vermassen, P., Goossens, S., Haigh, K., Cazzola, S., Lambert, J., Huylebroeck, D., Haigh, J. J. & Berx, G., 2014, In : Cellular and Molecular Life Sciences. 71, 18, p. 3599-3609 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2013

ADAMTS13 antibody depletion by bortezomib in thrombotic thrombocytopenic purpura

Shortt, J., Oh, D. H. & Opat, S., 2013, In : New England Journal of Medicine. 368, 1, p. 90 - 92 3 p.

Research output: Contribution to journalLetterOther

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein ibalpha

Kruss, S., Erpenbeck, L., Amschler, K., Mundinger, T. A., Boehm, H., Helms, H. J., Friede, T., Andrews, R. K., Schon, M. & Spatz, J. P., 2013, In : ACS Nano. 7, 11, p. 9984 - 9996 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green, B. D., Jabbour, A. M., Sandow, J. J., Riffkin, C. D., Masouras, D., Daunt, C. P., Salmanidis, M., Brumatti, G., Hemmings, B., Guthridge, M. A., Pearson, R. B. & Ekert, P. G., 2013, In : Cell Death and Differentiation. 20, 10, p. 1341 - 1349 9 p.

Research output: Contribution to journalArticleResearchpeer-review