Research Output 1984 2019

2015

An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model

Van Overbeke, W., Wongsantichon, J., Everaert, I., Verhelle, A., Zwaenepoel, O., Loonchanta, A., Burtnick, L. D., De Ganck, A., Hochepied, T., Haigh, J. J., Cuvelier, C., Derave, W., Robinson, R. C. & Gettemans, J., 2015, In : Human Molecular Genetics. 24, 9, p. 2492 - 2507 16 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel role for the EMT regulator, snai1, in hematopoiesis and leukemia

Carmichael, C., Goossens, S., Kile, B. & Haigh, J. J., 2015, p. S56. 1 p.

Research output: Contribution to conferencePosterOtherpeer-review

Apixaban and patient management following stroke/tia: A consensus guide

Levi, C. R., Campbell, B. C. V., Lindley, R. I., Nandurkar, H. H., Parsons, M. W. & Hankey, G., 2015, p. 83.

Research output: Contribution to conferencePosterOtherpeer-review

Approval of the first protease-activated receptor antagonist: rationale, development, significance, and considerations of a novel anti-platelet agent

French, S., Arthur, J. F., Tran, H. A. & Hamilton, J. R., 2015, In : Blood Reviews. 29, 3, p. 179 - 189 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia

Kalff, A., Khong, T., Wall, M., Gorniak, M., Mithraprabhu, S., Campbell, L. J. & Spencer, A., 2015, In : Haematologica: the hematology journal. 100, 2, p. e60-e62 3 p.

Research output: Contribution to journalLetterOtherpeer-review

Open Access

Asymmetric cell division during T cell development controls downstream fate

Pham, K., Shimoni, R., Ludford-Menting, M. J., Hawkins, E., Ramsbottom, K. M., Oliaro, J., Izon, D. J., Ting, S. B. N., Reynolds, J. B., Lythe, G., Molina-Paris, C., Melichar, H. J., Robey, E., Humbert, P. O., Gu, M. & Russell, S. M., 2015, In : Journal of Cell Biology. 210, 6, p. 933 - 950 18 p.

Research output: Contribution to journalArticleResearchpeer-review

A transgenic mouse model to inducibly target prosurvival Bcl2 proteins with selective BH3 peptides in vivo

Lee, E. F., Takiguchi, M., Pettikiriarachchi, A., Evangelista, M., Huang, D. C. S., Dickins, R. A. & Fairlie, W. D., 12 Mar 2015, In : Cell Death and Disease. 6, 3 p., e1679.

Research output: Contribution to journalLetterResearchpeer-review

Open Access
File

Bromelain and N-acetylcysteine inhibit proliferation and survival of gastrointestinal cancer cells: significance of combination therapy

Amini, A., Masoumi Moghaddam, S. & Morris, D. L., 2015.

Research output: Contribution to conferencePosterOtherpeer-review

Chemotherapy plus lenalidomide versus autologous transplantation, followed by lenalidomide plus prednisone versus lenalidomide maintenance, in patients with multiple myeloma: A randomised, multicentre, phase 3 trial

Gay, F., Oliva, S., Petrucci, M. T., Conticello, C., Catalano, L., Corradini, P., Siniscalchi, A., Magarotto, V., Pour, L., Carella, A-M., Malfitano, A., Petrò, D., Evangelista, A., Spada, S., Pescosta, N., Omedè, P., Campbell, P., Liberati, A. M., Offidani, M., Ria, R. & 6 others, Pulini, S., Patriarca, F., Hajek, R., Spencer, A., Boccadoro, M. & Palumbo, A., 2015, In : Lancet Oncology. 16, 16, p. 1617-1629 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Class II but not second class - prospects for the development of class II PI3K inhibitors

Mountford, S. J., Zheng, Z., Sundaram, K., Jennings, I., Hamilton, J. R. & Thompson, P., 2015, In : A C S Medicinal Chemistry Letters. 6, 1, p. 3 - 6 4 p.

Research output: Contribution to journalEditorialResearchpeer-review

Comparison of biosimilar filgrastim with originator filgrastim for peripheral blood stem cell mobilization and engraftment in patients with multiple myeloma undergoing autologous stem cell transplantation

Pham, T., Patil, S., Fleming, S. A., Avery, S., Walker, P. A., Wei, A., Curtis, D. J., Stuart, G., Klarica, D., O'Brien, M., Morris, K., Das, T. P., Bollard, G. M., Muirhead, J., Coutsouvelis, J. & Spencer, A., 2015, In : Transfusion. 55, 11, p. 2709 - 2713 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran

Bouchard, J., Ghannoum, M., Bernier-Jean, A., Williamson, D. R., Kershaw, G., Weatherburn, C., Eris, J. M., Tran, H. A., Patel, J. P. & Roberts, D. M., 2015, In : Clinical Toxicology. 53, 3, p. 156 - 163 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Current state and novel approaches of antiplatelet therapy

Metharom, P., Berndt, M. C., Baker, R. I. & Andrews, R. K., 2015, In : Arteriosclerosis, Thrombosis and Vascular Biology. 35, 6, p. 1327 - 1338 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Cytokine Receptors and Their Ligands

Dhagat, U., Nero, T. L., Kan, W. L., Hercus, T. R., Broughton, S. E., De Weerd, N. A., Jenkins, B. J., Mansell, A., Guthridge, M. A., Hertzog, P. J., Lopez, A. F. & Parker, M. W., 1 Jan 2015, Encyclopedia of Cell Biology: Functional Cell Biology. Bradshaw, R. A. & Stahl, P. D. (eds.). Waltham MA USA: Elsevier, Vol. 3. p. 22-36 15 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Dendritic cell-mediated phagocytosis but not immune activation is enhanced by plasmin

Borg, R., Samson, A. L., Au, A. E-L., Scholzen, A., Fuchsberger, M., Kong, Y. Y., Freeman, R., Mifsud, N. A., Plebanski, M. & Medcalf, R. L., 2015, In : PLoS ONE. 10, 7 , 19 p., e0131216.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9

Phillipson, L. J., Segal, D., Nero, T. L., Parker, M. W., Wan, S. S., de Silva, M., Guthridge, M. A., Wei, A. & Burns, C. J., 2015, In : Bioorganic & Medicinal Chemistry. 23, 19 (Art. No: 12539), p. 6280 - 6296 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Disseminated Enteroviral Infection Associated with Obinutuzumab

Dendle, C., Gilbertson, M., Korman, T., Golder, V., Morand, E. F. & Opat, S., 2015, In : Emerging infectious diseases. 21, 9, p. 1661 - 1663 3 p.

Research output: Contribution to journalArticleOther

Dynamic evaluation and control of blood clotting using a microfluidic platform for high-throughput diagnostics

Combariza, M. E., Yu, X., Nesbitt, W., Tovar-Lopez, F., Rabus, D. G. & Mitchell, A., 1 Jan 2015, Micro+Nano Materials, Devices, and Systems. Palomba, S. & Eggleton, B. J. (eds.). Bellingham WA USA: SPIE, 10 p. 96681U. (Proceedings of SPIE; vol. 9668).

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Editorial: ADAMs control inflammation from afar

Andrews, R. K. & Gardiner, E. E., 2015, In : Journal of leukocyte biology. 97, 3, p. 437 - 438 2 p.

Research output: Contribution to journalLetterOther

Effects of abacavir administration on structural and functional markers of platelet activation

Trevillyan, J. M., Arthur, J. F., Jing, J., Andrews, R. K., Gardiner, E. E. & Hoy, J. F., 2015, In : AIDS. 29, 17, p. 2309 - 2313 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficacy of an Fc-modified anti-CD123 antibody (CSL362) combined with chemotherapy in xenograft models of acute myelogenous leukemia in immunodeficient mice

Lee, E. M., Yee, D., Busfield, S. J., McManus, J. F., Cummings, N. J., Vairo, G., Wei, A., Ramshaw, H. S., Powell, J. A., Lopez, A. F., Lewis, I. D., McCall, M. N. & Lock, R. B., 2015, In : Haematologica: the hematology journal. 100, 7, p. 914 - 926 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Erratum for the research article: "Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia"

Lim, Y., Gondek, L., Li, L., Wang, Q., Ma, H., Chang, E., Huso, D. L., Foerster, S., Marchionni, L., McGovern, K., Watkins, D. N., Peacock, C. D., Levis, M., Smith, B. D., Merchant, A. A., Small, D. & Matsui, W., 8 Jul 2015, In : Science Translational Medicine. 7, 295, 295er6.

Research output: Contribution to journalComment / DebateOtherpeer-review

Evaluation of gait impairment in mice subjected to craniotomy and traumatic brain injury

Sashindranath, M., Daglas, M. & Medcalf, R. L., 2015, In : Behavioural Brain Research. 286, p. 33 - 38 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Expression of Sprouty 1 protein is downregulated in human epithelial ovarian cancer and associated with clinicopathological features and patient outcome

Masoumi Moghaddam, S., Amini, A., Wei, A-Q. & Morris, D. L., 2015.

Research output: Contribution to conferencePosterOtherpeer-review

Extracorporeal membrane oxygenation-hemostatic complications

Murphy, D. A., Hockings, L. E., Andrews, R. K., Aubron, C., Gardiner, E. E., Pellegrino, V. & Davis, A. K., 2015, In : Transfusion Medicine Reviews. 29, 2, p. 90 - 101 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Global Coagulation Assays in the Normal Population: Female Gender, Older Age and East Asian Ethnicity Associated with Prothrombotic Parameters.

Ho, P., Lim, H. Y., Ng, C., Smith, C. L., Donnan, G. & Nandurkar, H. H., 2015, p. 4678.

Research output: Contribution to conferenceAbstractOtherpeer-review

Global regulator MorA affects virulence-associated protease secretion in Pseudomonas aeruginosa PAO1

Ravichandran, A., Ramachandran, M., Suriyanarayanan, T., Wong, C. C. & Swarup, S., 2015, In : PLoS ONE. 10, 4, p. 1 - 17 17 p., 0123805.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine on mucin-expressing gastrointestinal cancer cells in vitro and in vivo

Amini, A., Masoumi Moghaddam, S., Ehteda, A. & Morris, D. L., 2015.

Research output: Contribution to conferencePosterOtherpeer-review

Grp78 injection ameliorates haemolytic uraemic syndrome (hus) phenotype in a suburb toxin induced mouse model.

Kamel, S., Freddi, S., Selan, C., Samudra, A. N., Sharma, A., Nandurkar, H. H. & Cowan, P., 2015, p. 75-76.

Research output: Contribution to conferenceAbstractOtherpeer-review

Imatinib treatment reduces brain injury in a murine model of traumatic brain injury

Su, E. J., Fredriksson, L. T., Kanzawa, M., Moore, S., Folestad, E., Stevenson, T. K., Nilsson, I., Sashindranath, M., Schielke, G. P., Warnock, M., Ragsdale, M., Mann, K. M., Lawrence, A-L. E., Medcalf, R. L., Eriksson, U., Murphy, G. G. & Lawrence, D. A., 2015, In : Frontiers in Cellular Neuroscience. 9, (Art. No: 385), p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Impact of maintenance therapy on subsequent treatment in patients with newly diagnosed multiple myeloma: Use of “progression-free survival 2” as a clinical trial end-point

Dimopoulos, M. A., Petrucci, M. T., Foà, R., Catalano, J., Kropff, M., Terpos, E., Zhang, J., Grote, L., Jacques, C. & Palumbo, A., 5 Aug 2015, In : Haematologica: the hematology journal. 100, 8, p. e328-e330 3 p.

Research output: Contribution to journalLetterResearchpeer-review

Open Access

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

Rijal, S., Fleming, S., Cummings, N., Rynkiewicz, N., Ooms, L. M., Nguyen, N-Y. N., Teh, T-C., Avery, S., McManus, J., Papenfuss, A. T., McLean, C. A., Guthridge, M. A., Mitchell, C. A. & Wei, A., 30 Apr 2015, In : Blood. 125, 18, p. 2815-2824 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Intravascular leukocyte migration through platelet thrombi: directing leukocytes to sites of vascular injury

Ghasemzadeh, M. & Hosseini, E., 2015, In : Thrombosis and Haemostasis. 113, 6, p. 1224 - 1235 12 p.

Research output: Contribution to journalArticleResearchpeer-review

In vivo assessment of growth inhibitory and mucin depleting effects of bromelain and N-acetylcysteine in peritoneal carcinomatosis models

Amini, A., Masoumi Moghaddam, S. & Morris, D. L., 2015.

Research output: Contribution to conferencePosterOtherpeer-review

Loss of c-REL but not NF-{kappa}B2 prevents autoimmune disease driven by FasL mutation

O'Reilly, L. A., Hughes, P. D., Lin, A., Waring, P. M., Siebenlist, U., Jain, R., Gray, D. H. D., Gerondakis, S. D. & Strasser, A., 2015, In : Cell Death and Differentiation. 22, 5, p. 767 - 778 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Low levels of CD9 coincidental with a novel nonsense mutation in glycoprotein Ib? in a patient with Bernard-Soulier syndrome

Qiao, J. L., Davis, A. K., Morel-Kopp, M-C., Ward, C., Gardiner, E. E. & Andrews, R. K., 2015, In : Annals of Hematology. 94, 12, p. 2069 - 2071 3 p.

Research output: Contribution to journalArticleOther

Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression

Martin, A., Salvador, F., Moreno-Bueno, G., Floristan, A., Ruiz-Herguido, C., Cuevas, E. P., Morales, S., Santos, V., Csiszar, K., Dubus, P., Haigh, J. J., Bigas, A., Portillo, F. & Cano, A., 2015, In : EMBO Journal. 34, 8, p. 1090 - 1109 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Maintenance lenalidomide in combination with 5-azacitidine as post-remission therapy for acute myeloid leukaemia

Wei, A., Tan, P. T. G., Perruzza, S. N., Govindaraj, C., Fleming, S. A., McManus, J. F., Avery, S., Patil, S., Stevenson, W. C., Plebanski, M. & Spencer, A., 2015, In : British Journal of Haematology. 169, 2, p. 199 - 210 12 p.

Research output: Contribution to journalArticleResearchpeer-review

MDX-1097 induces antibody-dependent cellular cytotoxicity against kappa multiple myeloma cells and its activity is augmented by lenalidomide

Asvadi, P., Cuddihy, A. R., Dunn, R., Jiang, V., Wong, M. X., Jones, D. R., Khong, T. T. F. & Spencer, A., 2015, In : British Journal of Haematology. 169, 3, p. 333 - 343 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods for understanding shear induced thrombus growth

Pinar, I. P., Arthur, J., Andrews, R., Gardiner, E. E., Ryan, K. & Carberry, J. J., 1 Jan 2015, Ninth International Symposium on Turbulence and Shear Flow Phenomena (TSFP-9). Tavoularis, S. & Marusic, I. (eds.). Melbourne Vic Australia: University of Melbourne, p. 1-5 5 p. (9th International Symposium on Turbulence and Shear Flow Phenomena, TSFP 2015; vol. 2).

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Methods to determine the lagrangian shear experienced by platelets during thrombus growth

Pinar, I., Arthur, J. F., Andrews, R. K., Gardiner, E. E., Ryan, K. & Carberry, J. J., 2015, In : PLoS ONE. 10, 12, p. 1 - 14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes

McQuilten, Z., Sundararajan, V., Andrianopoulos, N., Curtis, D. J., Wood, E. M., Campbell, L. J. & Wall, M., 2015, In : Cancer. 121, 17, p. 2892 - 2899 8 p.

Research output: Contribution to journalArticleResearchpeer-review

MouseMove: an open source program for semi-automated analysis of movement and cognitive testing in rodents

Samson, A. L., Ju, L., Kim, H. A., Zhang, S., Lee, J. A. A., Sturgeon, S. A., Sobey, C. G., Jackson, S. & Schoenwaelder, S. M., 2015, In : Scientific Reports. 5, (Art. No: 16171), p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Müller glia are a major cellular source of survival signals for retinal neurons in diabetes

Fu, S., Dong, S., Zhu, M., Sherry, D. M., Wang, C., You, Z., Haigh, J. J. & Le, Y-Z., 2015, In : Diabetes. 64, 10, p. 3554-3563 10 p.

Research output: Contribution to journalArticleResearchpeer-review

MYB elongation is regulated by the nucleic acid binding of NF?B p50 to the intronic stem-loop region

Pereira, L. A., Hugo, H. J., Malaterre, J., Xu, H., Sonza, S., Cures, A., Purcell, D. F. J., Ramsland, P. A., Gerondakis, S. D., Gonda, T. J. & Ramsay, R. G., 2015, In : PLoS ONE. 10, 4 (Art. No: e0122919), p. 1 - 25 25 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

NF-κB1, NF-κB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice

Burkitt, M. D., Hanedi, A. F., Duckworth, C. A., Williams, J. M., Tang, J. M., O'Reilly, L. A., Putoczki, T. L., Gerondakis, S., Dimaline, R., Caamano, J. H. & Mark Pritchard, D., 1 Jul 2015, In : Journal of Pathology. 236, 3, p. 326-336 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Novel biological insights in T-cell acute lymphoblastic leukemia

Durinck, K., Goossens, S., Peirs, S., Wallaert, A., Loocke, W. V., Matthijssens, F., Pieters, T., Milani, G., Lammens, T., Rondou, P., Roy, N. V., Moerloose, B. D., Benoit, Y., Haigh, J., Speleman, F. P., Poppe, B. & Van Vlierberghe, P., 2015, In : Experimental Hematology. 43, 8, p. 625-639 15 p.

Research output: Contribution to journalArticleResearchpeer-review

NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

Kim, K., Li, J., Tseng, A., Andrews, R. K. & Cho, J., 2015, In : Blood. 126, 16, p. 1952 - 1964 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Overcoming quiescence by targeting p21 (Cdkn1a) sensitizes pre-leukemic stem cells to chemotherapy

Tremblay, C., Saw, J. M. Y., Chiu, S. K. & Curtis, D. J., 1 Sep 2015, p. S45. 1 p.

Research output: Contribution to conferenceAbstractOtherpeer-review