Aust Ctr for Blood Diseases

Research Output 1984 2019

2017

Significant age, race and gender differences in global coagulation assays parameters in the normal population

Ho, P., Ng, C., Rigano, J., Tacey, M., Smith, C., Donnan, G. & Nandurkar, H., 1 Jun 2017, In : Thrombosis Research. 154, p. 80-83 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Soluble glycoprotein VI, a specific marker of platelet activation is increased in the plasma of subjects with seropositive rheumatoid arthritis

Stack, J. R., Madigan, A., Helbert, L., Dunne, E., Gardiner, E. E., Andrews, R. K., Finan, R., Smyth, E., Kenny, D. & McCarthy, G. M., 1 Nov 2017, In : PLoS ONE. 12, 11, 8 p., e0188027.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Specification of neurotransmitter identity by Tal1 in thalamic nuclei

Lee, B., Lee, M., Song, S., Loi, L. D., Lam, D. T., Yoon, J., Baek, K., Curtis, D. J. & Jeong, Y., 1 Oct 2017, In : Developmental Dynamics. 246, 10, p. 749-758 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange

Pieters, T., Haenebalcke, L., Bruneel, K., Vandamme, N., Hochepied, T., van Hengel, J., Wirth, D., Berx, G., Haigh, J. J., Van Roy, F. & Goossens, S., 27 Apr 2017, In : Journal of Visualized Experiments. 122, 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and biological evaluation of 8-aryl-2-morpholino-7-O-substituted benzo[e][1,3]oxazin-4-ones against DNA-PK, PI3K, PDE3A enzymes and platelet aggregation

Saifuzzaman, M., Morrison, R., Zheng, Z., Orive, S., Hamilton, J., Thompson, P. E. & Al-Rawi, J. M. A., 15 Oct 2017, In : Bioorganic and Medicinal Chemistry. 25, 20, p. 5531-5536 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeted therapies for T-cell acute lymphoblastic leukaemia (T-ALL): what makes T-ALL TYK?

Curtis, D. J., 1 Apr 2017, In : British Journal of Haematology. 177, 2, p. 169-170 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Powell, J. A., Lewis, A. C., Zhu, W., Toubia, J., Pitman, M. R., Wallington-Beddoe, C. T., Moretti, P. A. B., Iarossi, D., Samaraweera, S. E., Cummings, N., Ramshaw, H. S., Thomas, D., Wei, A. H., Lopez, A. F., D'Andrea, R. J., Lewis, I. D. & Pitson, S. M., 9 Feb 2017, In : Blood. 129, 6, p. 771-782 12 p.

Research output: Contribution to journalArticleResearchpeer-review

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Moujalled, D., Grubman, A., Acevedo, K., Yang, S., Ke, Y. D., Moujalled, D. M., Duncan, C., Caragounis, A., Perera, N. D., Turner, B. J., Prudencio, M., Petrucelli, L., Blair, I., Ittner, L. M., Crouch, P. J., Liddell, J. R. & White, A. R., 1 May 2017, In : Human Molecular Genetics. 26, 9, p. 1732-1746 15 p., ddx093.

Research output: Contribution to journalArticleResearchpeer-review

The cutting edge of platelets

Andrews, R. K. & Gardiner, E. E., 19 May 2017, In : Platelets. 28, 4, p. 317-318 2 p.

Research output: Contribution to journalArticleOtherpeer-review

The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling

Li, J., Riedt, T., Goossens, S., García, C. C., Szczepanski, S., Brandes, M., Pieters, T., Dobrosch, L., Gütgemann, I., Farla, N., Radaelli, E., Hulpiau, P., Mallela, N., Fröhlich, H., La Starza, R., Matteucci, C., Chen, T., Brossart, P., Mecucci, C., Huylebroeck, D. & 2 othersHaigh, J. J. & Janzen, V., 26 Jan 2017, In : Blood. 129, 4, p. 460-472 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The fibrinolysis inhibitor α2-antiplasmin restricts lymphatic remodelling and metastasis in a mouse model of cancer

Paquet-Fifield, S., Roufail, S., Zhang, Y. F., Sofian, T., Byrne, D. J., Coughlin, P. B., Fox, S. B., Stacker, S. A. & Achen, M. G., 11 Jul 2017, In : Growth Factors. 35, 2-3, p. 61-75 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia

Fox, L. C., Cummins, K. D., Costello, B., Yeung, D., Cleary, R., Forsyth, C., Tatarczuch, M., Burbury, K., Motorna, O., Shortt, J., Fleming, S., McQuillan, A., Schwarer, A., Harrup, R., Holmes, A., Ratnasingam, S., Chan, K-L., Hsu, W-H., Ashraf, A., Putt, F. & 1 othersGrigg, A. P., 23 May 2017, In : Blood Advances. 1, 13, p. 802-811 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia: a phase Ib/II study

Tan, P., Tiong, I. S., Fleming, S., Pomilio, G., Cummings, N., Droogleever, M., McManus, J., Schwarer, A., Catalano, J., Patil, S., Avery, S., Spencer, A. & Wei, A., 2017, In : Oncotarget. 8, 32, p. 52269-52280 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

The Patients’ Perspective: Hematological Cancer Patients’ Experiences of Adverse Events as Part of Care

Bryant, J., Carey, M., Sanson-Fisher, R., Turon, H., Wei, A. & Kuss, B., 17 Mar 2017, (Accepted/In press) In : Journal of Patient Safety.

Research output: Contribution to journalArticleResearchpeer-review

The Snail Family in Normal and Malignant Haematopoiesis

Carmichael, C. L. & Haigh, J. J., 1 Feb 2017, In : Cells Tissues Organs. 203, 2, p. 82-98 17 p.

Research output: Contribution to journalArticleResearchpeer-review

To the editor: Venetoclax and obinutuzumab in chronic lymphocytic leukemia

Fischer, K., Al-Sawaf, O., Fink, A. M., Dixon, M., Bahlo, J., Warburton, S., Kipps, T. J., Weinkove, R., Robinson, S., Seiler, T., Opat, S., Owen, C. J., López, J., Humphrey, K., Humerickhouse, R., Tausch, E., Frenzel, L., Eichhorst, B., Wendtner, C. M., Stilgenbauer, S. & 7 othersLangerak, A. W., Van Dongen, J. J. M., Böttcher, S., Ritgen, M., Goede, V., Mobasher, M. & Hallek, M., 11 May 2017, In : Blood. 129, 19, p. 2702-2705 4 p.

Research output: Contribution to journalLetterOtherpeer-review

tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS

Fredriksson, L., Lawrence, D. A. & Medcalf, R. L., 1 Mar 2017, In : Seminars in Thrombosis and Hemostasis. 43, 2, p. 154-168 15 p., 02355.

Research output: Contribution to journalArticleResearchpeer-review

Triggered and Tunable Hydrogen Sulfide Release from Photogenerated Thiobenzaldehydes

Xiao, Z., Bonnard, T., Shakouri-Motlagh, A., Wylie, R. A. L., Collins, J., White, J., Heath, D. E., Hagemeyer, C. E. & Connal, L. A., 22 Aug 2017, In : Chemistry - A European Journal. 23, 47, p. 11294-11300 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Up-Regulation of the Vitamin D Pathway in Acute Myeloid Leukemia: A Novel Cause of Hypercalcemia

Casan, J. M. L., Ghoth, S., Wei, A. H., Ting, S. B. & Morgan, S., 2017, In : Annals of Hematology and Oncology. 4, 3, 1141.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Utility of CRISPR/Cas9 systems in hematology research

Lucas, D., O'Leary, H. A., Ebert, B. L., Cowan, C. A. & Tremblay, C. S., Oct 2017, In : Experimental Hematology. 54, p. 1-3 3 p.

Research output: Contribution to journalArticleOtherpeer-review

Venous thromboembolism management in Northeast Melbourne: how does it compare to international guidelines and data?

Lim, H. Y., Chua, C. C., Tacey, M., Sleeman, M., Donnan, G., Nandurkar, H. & Ho, P., 1 Sep 2017, In : Internal Medicine Journal. 47, 9, p. 1034-1042 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Zeb2 regulates cell fate at the exit from epiblast state in mouse embryonic stem cells

Stryjewska, A., Dries, R., Pieters, T., Verstappen, G., Conidi, A., Coddens, K., Francis, A., Umans, L., van Ijcken, W. F. J., Berx, G., van Grunsven, L. A., Grosveld, F., Goossens, S., Haigh, J. J. & Huylebroeck, D., Mar 2017, In : Stem Cells. 35, 3, p. 611-625 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

β-catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma

Savvidou, I., Khong, T., Cuddihy, A., McLean, C., Horrigan, S. & Spencer, A., 1 Sep 2017, In : Molecular Cancer Therapeutics. 16, 9, p. 1765-1778 14 p.

Research output: Contribution to journalArticleResearchpeer-review

‘Did He Who Made the Lamb Make Thee?’ New Developments in Treating the ‘Fearful Symmetry’ of Acute Myeloid Leukemia

Brumatti, G., Lalaoui, N., Wei, A. H. & Silke, J., 1 Mar 2017, In : Trends in Molecular Medicine. 23, 3, p. 264-281 18 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

2016

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

Schoenwaelder, S. M., Darbousset, R., Cranmer, S. L., Ramshaw, H. S., Orive, S. L., Sturgeon, S., Yuan, Y., Yao, Y., Krycer, J. R., Woodcock, J. M., Maclean, J., Pitson, S., Zheng, Z., Henstridge, D. C., Van Der Wal, D., Gardiner, E. E., Berndt, M. C., Andrews, R. K., James, D. E., Lopez, A. F. & 1 othersJackson, S. P., 27 Sep 2016, In : Nature Communications. 7, 17 p., 12862.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury

Karve, I. P., Zhang, M., Habgood, M., Frugier, T., Brody, K. M., Sashindranath, M., Ek, C. J., Chappaz, S., Kile, B. T., Wright, D., Wang, H., Johnston, L., Daglas, M., Ates, R. C., Medcalf, R. L., Taylor, J. M. & Crack, P. J., 1 Jan 2016, In : eNeuro. 3, 1, 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Abstract B39: PTP1B deficiency potentiate prostate cancer invasiveness by sensitizing Pten-null tumors to high-fat diet

Labbé, D. P., Uetani, N., Vinette, V., Aubry, I., Migon, E., Sirois, J., Haigh, J. J., Lessard, L., Bégin, L. R., Trotman, L. C., Paquet, M. & Tremblay, M. L., 2016, In : Molecular Cancer Research. 14, 1 Supplement, p. B39 1 p.

Research output: Contribution to journalArticleOtherpeer-review

Activation of protein phosphatase 2A in FLT3+ acute myeloid leukemia cells enhances the cytotoxicity of FLT3 tyrosine kinase inhibitors

Smith, A. M., Dun, M. D., Lee, E. M., Harrison, C., Kahl, R., Flanagan, H., Panicker, N., Mashkani, B., Don, A. S., Morris, J., Toop, H., Lock, R. B., Powell, J. A., Thomas, D., Guthridge, M. A., Moore, A., Ashman, L. K., Skelding, K. A., Enjeti, A. & Verrills, N. M., 2016, In : Oncotarget. 7, 30, p. 47465-47478 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A-disintegrin-and-metalloproteinase (ADAM) 10 activity on resting and activated platelets

Facey, A. D., Pinar, I., Arthur, J. F., Qiao, J. L., Jing, J., Mado, B., Carberry, J. J., Andrews, R. K. & Gardiner, E. E., 2016, In : Biochemistry. 55, 8, p. 1187 - 1194 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Anti-fibrinolytics

Draxler, D. F., Medcalf, R. L. & Gruen, R. L., 1 Jan 2016, Trauma Induced Coagulopathy. Gonzalez, E., Moore, H. B. & Moore, E. E. (eds.). Springer, p. 403-418 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

A Shear Micro-Gradient Microfluidic to Monitor Platelet Aggregation Dynamics in the Context of Von Willebrand Disease

Nandurkar, H., Nesbitt, W., Brazilek, R., Tovar-Lopez, F., Wong, A., Tran, H., Davis, A. & Mitchell, A., 2016, In : Blood. 128, 22, p. 3753-3753 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): And randomised, phase 3, open-label, multicentre study

Dimopoulos, M. A., Moreau, P., Palumbo, A., Joshua, D. E., Pour, L., Hájek, R., Facon, T., Ludwig, H., Oriol, A., Goldschmidt, H., Rosiñol, L., Straub, J., Suvorov, A., Araujo, C., Rimashevskaya, E., Pika, T., Gaidano, G., Weisel, K. C., Goranova-Marinova, V., Schwarer, A. & 11 othersMinuk, L., Masszi, T., Karamanesht, I., Offidani, M., Hungria, V., Spencer, A., Orlowski, R. Z., Gillenwater, H. H., Mohamed, N., Feng, S. & Chng, W. J., 1 Jan 2016, In : Lancet Oncology. 17, 1, p. 27-38 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Combined deficiency of PI3KC2α and PI3KC2β reveals a nonredundant role for PI3KC2α in regulating mouse platelet structure and thrombus stability

Petitjean, C., Setiabakti, N. M., Mountford, J. K., Arthur, J. F., Ellis, S. L. & Hamilton, J. R., 2016, In : Platelets. 27, 5, p. 402 - 409 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Correction: Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics (Cancer Cell (2016) 30(3) (499–500) (S1535610816000350) (10.1016/j.ccell.2016.01.006))

Lalaoui, N., Hänggi, K., Brumatti, G., Chau, D., Nguyen, N. Y. N., Vasilikos, L., Spilgies, L. M., Heckmann, D. A., Ma, C., Ghisi, M., Salmon, J. M., Matthews, G. M., de Valle, E., Moujalled, D. M., Menon, M. B., Spall, S. K., Glaser, S. P., Richmond, J., Lock, R. B., Condon, S. M. & 10 othersGugasyan, R., Gaestel, M., Guthridge, M., Johnstone, R. W., Munoz, L., Wei, A., Ekert, P. G., Vaux, D. L., Wong, W. W. L. & Silke, J., 12 Sep 2016, In : Cancer Cell. 30, 3, p. 499-500 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Daratumumab, bortezomib, and dexamethasone for multiple myeloma

Palumbo, A., Chanan-Khan, A., Weisel, K. C., Nooka, A. K., Masszi, T., Beksac, M., Spicka, I., Hungria, V., Munder, M., Mateos, M-V., Mark, T. M., Qi, M., Schecter, J., Amin, H., Qin, X., Deraedt, W., Ahmadi, T., Spencer, A. & Sonneveld, P., 25 Aug 2016, In : New England Journal of Medicine. 375, 8, p. 754-766 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia

Roboz, G. J., Montesinos, P., Selleslag, D., Wei, A., Jang, J. H., Falantes, J., Voso, M. T., Sayar, H., Porkka, K., Marlton, P., Almeida, A., Mohan, S., Ravandi, F., Garcia-Manero, G., Skikne, B. & Kantarjian, H. M., 1 Feb 2016, In : Future Oncology. 12, 3, p. 293-302 10 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Diagnosis and Management of Deep Vein Thrombosis and Pulmonary Embolism in Pregnancy

Bennett, A. & Chunilal, S., 1 Oct 2016, In : Seminars in Thrombosis and Hemostasis. 42, 7, p. 760-773 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Differentiation of human embryonic stem cells to HOXA + hemogenic vasculature that resembles the aorta-gonad-mesonephros

Ng, E., Azzola, L., Bruveris, F. F., Calvanese, V., Phipson, B., Vlahos, K., Hirst, C., Jokubaitis, V. J., Yu, Q. C., Maksimovic, J., Liebscher, S., Januar, V., Zhang, Z., Williams, B., Conscience, A., Durnall, J., Jackson, S., Costa, M., Elliott, D., Haylock, D. N. & 7 othersNilsson, S. K., Saffery, R., Schenke-Layland, K., Oshlack, A., Mikkola, H. K. A., Stanley, E. G. & Elefanty, A. G., 1 Nov 2016, In : Nature Biotechnology. 34, 11, p. 1168-1179 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)

Zheng, Z., Pinson, J. A., Mountford, S. J., Orive, S., Schoenwaelder, S. M., Shackleford, D., Powell, A., Nelson, E. M., Hamilton, J. R., Jackson, S., Jennings, I. G. & Thompson, P. E., 21 Oct 2016, In : European Journal of Medicinal Chemistry. 122, p. 339-351 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Editorial: The role of the plasminogen activating system in neurobiology

Medcalf, R. L. & Lawrence, D. A., 4 Oct 2016, In : Frontiers in Cellular Neuroscience. 10, OCT2016, 3 p., 222.

Research output: Contribution to journalEditorialOtherpeer-review

Epigenetic regulation of miRNA-124 and multiple downstream targets is associated with treatment response in myeloid malignancies

Liu, H. B., Pattie, P., Chandrasekara, S., Spencer, A. & Dear, A. E., Sep 2016, In : Oncology Letters. 12, 3, p. 2175-2180 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Epigenetics in the biology and treatment of multiple myeloma

Spencer, A. & Mithraprabhu, S., 2016, In : European Oncology & Haematology. 12, 2, p. 96-102 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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Evaluation of thromboelastography (teg) in patients with myeloproliferative neoplasm: platelet count> 600 (x109/L) associated with prothrombotic parameters

Smith, C., Hayes, L., Grigg, A., Nandurkar, H. & Ho, P., 2016. 1 p.

Research output: Contribution to conferenceAbstractOther

Evaluation of thromboelastography (teg) in patients with myeloproliferative neoplasm (mpn): platelet count> 600 associated with prothrombotic parameters.

Ng, C., Smith, C., Hayes, L., Grigg, L., Nandurkar, H. H. & Ho, P., 2016, p. S14.

Research output: Contribution to conferenceAbstractOtherpeer-review

Fabrication of complex PDMS microfluidic structures and embedded functional substrates by one-step injection moulding

Szydzik, C., Niego, B., Dalzell, G., Knoerzer, M., Ball, F., Nesbitt, W. S., Medcalf, R. L., Khoshmanesh, K. & Mitchell, A., 2016, In : RSC Advances. 6, 91, p. 87988-87994 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Forget about thrombosis: Platelets and Alzheimer's disease, yet another sticky situation

Mcfadyen, J. & Peter, K., 24 May 2016, In : Science Signaling. 9, 429, 3 p., fs9.

Research output: Contribution to journalArticleOtherpeer-review

GAPTrap: A Simple Expression System for Pluripotent Stem Cells and Their Derivatives

Kao, T., Labonne, T., Niclis, J. C., Chaurasia, R., Lokmic, Z., Qian, E., Bruveris, F. F., Howden, S. E., Motazedian, A., Schiesser, J. V., Costa, M., Sourris, K., Ng, E., Anderson, D., Giudice, A., Farlie, P., Cheung, M. M. H., Lamande, S. R., Penington, A. J., Parish, C. L. & 5 othersThomson, L. H., Rafii, A., Elliott, D. A., Elefanty, A. G. & Stanley, E. G., 13 Sep 2016, In : Stem Cell Reports. 7, 3, p. 518-526 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Heavy menstrual bleeding and dysmenorrhea are improved by magentic resonance guided focused ultrasound surgery (mrgfus) of adenomyosis

Jayaram, R., Subbarayan, K., Mithraprabhu, S. & Govindarajan, M., May 2016, In : Fertility Research and Practice. 2, 7 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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