Research Output 1984 2019

2012

Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin

Samson, A. L., Knaupp, A. S., Sashindranath, M., Borg, R. J., Au, A. E-L., Cops, E. J., Saunders, H. M., Cody, S. H., McLean, C. A., Nowell, C., Hughes, V. A., Bottomley, S. P. & Medcalf, R. L., 2012, In : Cell Reports. 2, 4, p. 889 - 901 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Overcoming aspirin treatment failure in diabetes

Linden, M. D. & Tran, H. A., 2012, In : Critical Reviews in Clinical Laboratory Sciences. 49, 5-6, p. 183 - 198 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Parvovirus B19-induced pure red cell aplasia in a heart transplant recipient

Fong, C. Y. & Kaplan, Z. S., 25 Oct 2012, In : Blood. 120, 17, p. 3395 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
File

Pathologic shear triggers shedding of vascular receptors: A novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels

Al-Tamimi, M., Tan, C. W., Qiao, J. L., Pennings, G., Javadzadegan, A., Yong, A., Arthur, J. F., Davis, A., Jing, J., Mu, F-T., Hamilton, J. R., Jackson, S., Ludwig, A., Berndt, M. C., Ward, C., Kritharides, L., Andrews, R. K. & Gardiner, E. E., 2012, In : Blood. 119, 18, p. 4311 - 4320 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Physiology, pharmacology, and therapeutic potential of protease-activated receptors in vascular disease

Lee, H. & Hamilton, J. R., 2012, In : Pharmacology and Therapeutics. 134, 2, p. 246 - 259 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasminogen activation and thrombolysis for ischemic stroke

Medcalf, R. L. & Davis, S. M., 2012, In : International Journal of Stroke. 7, 5, p. 419 - 425 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Platelet receptor shedding

Gardiner, E., Al-Tamimi, M., Andrews, R. & Berndt, M., 2012, In : Methods in Molecular Biology. 788, p. 321 - 339 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Primed for the kill: occupying Bcl-2 to target death in acute myeloid leukaemia

Wei, A. & Teh, T-C., 2012, In : BioDiscovery. 6, 2, p. 1 - 4 4 p.

Research output: Contribution to journalLetterOther

Recombinant human erythropoietin and darbepoietin alpha exerts differential effects on non-erythroid haemopoietic cells and bone marrow microenvironment.

Dewamitta, S., Lim, H., Singbrant, S., Russell, M., Mullally, A., Ebert, B., Nandurkar, H. H. & Walkey, C., 2012, p. 97-98. 2 p.

Research output: Contribution to conferenceAbstractOtherpeer-review

Recommendations for the diagnosis and treatment of deep venous thrombosis and pulmonary embolism in pregnancy and the postpartum period

McLintock, C., Brighton, T., Chunilal, S., Dekker, G., McDonnell, N., McRae, S., Muller, P., Tran, H., Walters, B. & Young, L., 2012, In : Australian and New Zealand Journal of Obstetrics and Gynaecology. 52, 1, p. 14 - 22 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Recommendations for the prevention of pregnancy-associated venous thromboembolism

McLintock, C., Brighton, T., Chunilal, S., Dekker, G., McDonnell, N., McRae, S., Muller, P., Tran, H., Walters, B. & Young, L., 2012, In : Australian and New Zealand Journal of Obstetrics and Gynaecology. 52, 1, p. 3 - 13 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulation of delta-aminolevulinic acid dehydratase by kruppel-like factor 1

Desgardin, A. D., Abramova, T., Rosanwo, T. O., Kartha, S., Shim, E-H., Jane, S. M. & Cunningham, J., 2012, In : PLoS ONE. 7, 10, 11 p., e46482.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbalpha antibodies

Zeng, Q., Zhu, L., Tao, L., Bao, J., Yang, M., Simpson, E. K., Li, C., van der Wal, E., Chen, P., Springob, C. M., Wang, M., Zhang, L., Ruan, C., Hou, M., Xia, R. & Ni, H., 2012, In : American Journal of Hematology. 87, 2, p. 206 - 208 3 p.

Research output: Contribution to journalLetterOther

Restoring PML tumor suppression to combat cancer

Wolyniec, K., Chan, A-L., Haupt, S. & Haupt, Y., 15 Oct 2012, In : Cell Cycle. 11, 20, p. 3705-3706 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression

Larsson, P., Ulfhammer, E., Magnusson, M., Bergh, N., Lunke, S., El-Osta, A., Medcalf, R. L., Svensson, P. A., Karlsson, L. & Jern, S., Feb 2012, In : PLoS ONE. 7, 2 , 9 p., e31573.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Safety and efficacy of targeting platelet proteinase-activated receptors in combination with existing anti-platelet drugs as antithrombotics in mice

Lee, H., Sturgeon, S. A., Mountford, J. K., Jackson, S. & Hamilton, J. R., 2012, In : British Journal of Pharmacology. 166, 7, p. 2188 - 2197 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Serum protein electrophoresis: A precautionary tale

Grigoriadis, G., Shortt, J., Quach, H. & Opat, S., 2012, In : Pathology. 44, 4, p. 371 - 373 3 p.

Research output: Contribution to journalLetterOther

Staphylococcal superantigen-like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti-SSL5 antibody and the glycan Bimosiamose

Armstrong, P. CJ., Hu, H., Rivera, J., Rigby, S., Chen, Y. C., Howden, B. P., Gardiner, E. E. & Peter, K., 2012, In : Journal of Thrombosis and Haemostasis. 10, 12, p. 2607 - 2609 3 p.

Research output: Contribution to journalArticleResearchpeer-review

The contribution of thrombin-induced platelet activation to thrombus growth is diminished under pathological blood shear conditions

Lee, H., Sturgeon, S., Jackson, S. & Hamilton, J., 2012, In : Thrombosis and Haemostasis. 107, 2, p. 328 - 337 10 p.

Research output: Contribution to journalArticleResearchpeer-review

The impact of HLA-E polymorphisms in graft-versus-host disease following HLA-E matched allogeneic hematopoietic stem cell transplantation

Hosseini, E., Schwarer, A. & Ghasemzadeh, M., 2012, In : Iranian Journal of Allergy, Asthma and Immunology. 11, 1, p. 15 - 21 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The NET effect of clot formation

Gardiner, E., Ward, C. & Andrews, R., 2012, In : Journal of Thrombosis and Haemostasis. 10, p. 133 - 135 3 p.

Research output: Contribution to journalLetterOther

The NF-[kappa]B1 transcription factor prevents the intrathymic development of CD8 T cells with memory properties

Gugasyan, R., Horat, E., Kinkel, S., Ross, F., Grigoriadis, G., Gray, D., O'Keeffe, M., Berzins, S., Belz, G., Grumont, R., Banerjee, A., Strasser, A., Godfrey, D., Tsichlis, P. & Gerondakis, S., 2012, In : EMBO Journal. 31, 3, p. 692 - 706 15 p.

Research output: Contribution to journalArticleResearchpeer-review

The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans

Sashindranath, M., Sales, E., Daglas, M., Freeman, R., Samson, A. L., Cops, E., Beckham, S. A., Galle, A. A., McLean, C. A., Morganti-Kossmann, M. C., Rosenfeld, J. V., Madani, R., Vassalli, J-D., Su, E. J., Lawrence, D. A. & Medcalf, R. L., 2012, In : Brain. 135, 11, p. 3251 - 3264 14 p.

Research output: Contribution to journalArticleResearchpeer-review

The x-ray crystal structure of full-length human plasminogen

Law, R. HP., Caradoc-Davies, T. T., Cowieson, N. P., Horvath, A. J., Quek, A. J., Amarante Da Encarnacao, J., Steer, D. L., Cowan, A. D., Zhang, Q., Lu, B. GC., Pike, R. N., Smith, A. I., Coughlin, P. B. & Whisstock, J. C., 2012, In : Cell Reports. 1, 3, p. 185 - 190 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Tissue plasminogen activator does not alter development of acquired epilepsy

Tan, M-L., Ng, A. Q. P., Pandher, P., Sashindranath, M., Hamilton, J. A., Davis, S. M., O'Brien, T. J., Medcalf, R. L., Yan, B. & Jones, N., 2012, In : Epilepsia. 53, 11, p. 1998 - 2004 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue-type plasminogen activator regulates the neuronal uptake of glucose in the ischemic brain

Wu, F., Wu, J., Nicholson, A., Echeverry, R., Haile, W., Catano, M., An, J., Lee, A., Duong, D., Dammer, E., Seyfried, N. T., Tong, F. C., Votaw, J. R., Medcalf, R. L. & Yepes, M., 2012, In : Journal of Neuroscience. 32, 29, p. 9848 - 9858 11 p.

Research output: Contribution to journalArticleResearchpeer-review

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

Niego, B., Freeman, R., Puschmann, T., Turnley, A. & Medcalf, R. L., 2012, In : Blood. 119, 20, p. 4752 - 4761 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor

Young, L., Birch, N., Browett, P. J., Coughlin, P. B., Horvath, A. J., van de Water, N. S., Ockelford, P. A. & Harper, P. L., 2012, In : Thrombosis and Haemostasis. 107, 5, p. 854 - 863 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Vacuum flow focusing microfluidics to study blood cell dynamics under shear gradient aggregation mechanism

Tovar-Lopez, F. J., Nasabi, M., Sivan, V., Khoshmanesh, K., Jackson, S., Rosengarten, G., Mitchell, A. & Nesbitt, W. S., 1 Jan 2012, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012. Chemical and Biological Microsystems Society, p. 740-742 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Validation of whole blood impedance aggregometry as a new diagnostic tool for HIT: Results of a large Australian study

Morel-Kopp, M-C., Tan, C. W., Brighton, T., McRae, S., Baker, R. I., Tran, H. A., Mollee, P. N., Kershaw, G., Joseph, J. E. & Ward, C., 2012, In : Thrombosis and Haemostasis. 107, 3, p. 575 - 583 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Wnt1 is anti-lymphangiogenic in a melanoma mouse model

Niederleithner, H., Heinz, M., Tauber, S., Bilban, M., Pehamberger, H., Sonderegger, S. E., Knofler, M., Bracher, A., Berger, W., Loewe, R. & Petzelbauer, P., 2012, In : Journal of Investigative Dermatology. 132, 9, p. 2235 - 2244 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

A case of ITP with cauda equina syndrome

Merriman, E., Nandurkar, D., Opat, S. & Tran, H., Jun 2011, In : Annals of Hematology. 90, 6, p. 729-730 2 p.

Research output: Contribution to journalLetterOtherpeer-review

A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model

Gaspari, T., Liu, H., Welungoda, I., Hu, Y., Widdop, R., Knudsen, L., Simpson, R. & Dear, A., 2011, In : Diabetes and Vascular Disease Research. 8, 2, p. 117 - 124 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue

Tjarnlund-Wolf, A., Hultman, K., Curtis, M., Faull, R., Medcalf, R. & Jern, C., 2011, In : Thrombosis and Haemostasis. 105, 6, p. 945 - 953 9 p.

Research output: Contribution to journalArticleResearchpeer-review

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nguyen, N-Y. N., Maxwell, M. J., Ooms, L., Davies, E. M., Hilton, A. A., Collinge, J. E., Hilton, D. J., Kile, B. T., Mitchell, C. A., Hibbs, M. L., Jane, S. M. & Curtis, D. J., 2011, In : Blood. 117, 20, p. 5362-5371 10 p., 20.

Research output: Contribution to journalArticleResearchpeer-review

An event of shear importance

Andrews, R. & Berndt, M., 2011, In : Blood. 117, 1, p. 5 - 7 3 p.

Research output: Contribution to journalLetterOther

Antiplatelet drugs, anticoagulants and elective surgery

Merriman, E. & Tran, H., 2011, In : Australian Prescriber. 34, 5, p. 139 - 143 5 p.

Research output: Contribution to journalArticleOther

Arterial thrombosis-insidious, unpredictable and deadly

Jackson, S., 2011, In : Nature Medicine. 17, 11, p. 1423 - 1436 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A sensitized RNA interference screen identifies a novel role for the PI3K p110I-gamma isoform in medulloblastoma cell proliferation and chemoresistance

Guerreiro, A., Fattet, S., Kulesza, D., Atamer, A., Elsing, A., Shalaby, T., Jackson, S., Schoenwaelder, S., Grotzer, M., Delattre, O. & Arcaro, A., 2011, In : Molecular Cancer Research. 9, 7, p. 925 - 935 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A systematic review of interventions for co-occurring substance use disorder and borderline personality disorder

Pennay, A. E., Cameron, J. J., Reichert, T., Strickland, H., Lee, N. & Lubman, D. I., 2011, In : Journal of Substance Abuse Treatment. 41, 4, p. 363 - 373 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Schoenwaelder, S. M., Jarman, K. E., Gardiner, E. E., Hua, M., Qiao, J., White, M. J., Josefsson, E. C., Alwis, I., Ono, A., Willcox, A., Andrews, R. K., Mason, K. D., Salem, H. H., Huang, D. C. S., Kile, B. T., Roberts, A. W. & Jackson, S. P., 2011, In : Blood. 118, 6, p. 1663-1674 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Bernard-Soulier syndrome

Berndt, M. & Andrews, R., 2011, In : Haematologica: the hematology journal. 96, 3, p. 355 - 359 5 p.

Research output: Contribution to journalLetterOther

Blood cell diffusion visualization using multiple hydrodynamic flow focusing

Tovar-Lopez, F. J., Rosengarten, G., Nasabi, M., Sivan, V., Jackson, S. P., Nesbitt, W. S. & Mitchell, A., 1 Dec 2011, 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011. Vol. 1. p. 45-47 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Cd39 over expression protects in a murine model of antiphospholipid antibody-induced miscarriages. Journal of Thrombosis and Haemostasis.

Nandurkar, H. H., Samudra, A. N., Sharma, A., Zhang, X. M., Selan, C., Dwyer, K. & Cowan, P., 2011, p. 291.

Research output: Contribution to conferenceAbstractOtherpeer-review

Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa

Al-Tamimi, M., Grigoriadis, G., Tran, H., Paul, E., Servadei, P., Berndt, M., Gardiner, E. E. & Andrews, R. K., 2011, In : Blood. 117, 14, p. 3912 - 3920 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Collagen surfaces to measure thrombus formation under flow: Possibilities for standardization

Heemskerk, J., Sakariassen, K., Zwaginga, J. J., Brass, L., Jackson, S. P. & Farndale, R., 2011, In : Journal of Thrombosis and Haemostasis. 9, 4, p. 856 - 858 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Compartment- and context-specific changes in tissue-type plasminogen activator (tPA) activity following brain injury and pharmacological stimulation

Sashindranath, M., Samson, A., Downes, C. E., Crack, P., Lawrence, A. J., Li, Q-X., Ng, A. Q. P., Jones, N. C., Farrugia, J., Abdella, E., Vassalli, J-D., Madani, R. & Medcalf, R., 2011, In : Laboratory Investigation. 91, 7, p. 1079 - 1091 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Contribution of conserved lysine residues in the alpha{2}-antiplasmin C terminus to plasmin binding and inhibition

Lu, B. G. C., Sofian, T., Law, R. HP., Coughlin, P. B. & Horvath, A. J., 2011, In : Journal of Biological Chemistry. 286, 28, p. 24544 - 24552 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Corrigendum

Arthur, J. F., Shen, Y., Gardiner, E. E., Coleman, L., Murphy, D., Kenny, D., Andrews, R. K. & Berndt, M. C., Dec 2011, In : Journal of Thrombosis and Haemostasis. 9, 12, p. 2523 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review