Research Output 1988 2019

2018

Characterization of Tfrc-mutant mice with microcytic phenotypes

Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 5, p. 1914-1922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Compression force sensing regulates integrin αiIbβ3 adhesive function on diabetic platelets

Ju, L., McFadyen, J. D., Al-Daher, S., Alwis, I., Chen, Y., Tønnesen, L. L., Maiocchi, S., Coulter, B., Calkin, A. C., Felner, E. I., Cohen, N., Yuan, Y., Schoenwaelder, S. M., Cooper, M. E., Zhu, C. & Jackson, S. P., 1 Dec 2018, In : Nature Communications. 9, 1, 16 p., 1087.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Considerations for pre-transfusion immunohaematology testing in patients receiving the anti-CD38 monoclonal antibody daratumumab for the treatment of multiple myeloma

Quach, H., Benson, S., Haysom, H., Wilkes, A. M., Zacher, N., Cole-Sinclair, M., Miles Prince, H., Mollee, P., Spencer, A., Joy Ho, P., Harrison, S. J., Lee, C., Augustson, B. & Daly, J., 1 Feb 2018, In : Internal Medicine Journal. 48, 2, p. 210-220 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Contemporary analysis of functional immune recovery to opportunistic and vaccine-preventable infections after allogeneic haemopoietic stem cell transplantation

De Silva, H., Ffrench, R. A., Korem, M., Orlowski-Oliver, E., Curtis, D. J., Spencer, A., Avery, S., Patil, S. & Morrissey, C. O., 1 Jan 2018, In : Clinical and Translational Immunology. 7, 10, 16 p., e1040.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Current and future antiplatelet therapies: Emphasis on preserving haemostasis

McFadyen, J. D., Schaff, M. & Peter, K., 1 Mar 2018, In : Nature Reviews Cardiology. 15, 3, p. 181-191 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: Updated analysis of CASTOR

Spencer, A., Lentzsch, S., Weisel, K., Avet-Loiseau, H., Mark, T. M., Spicka, I., Masszi, T., Lauri, B., Levin, M. D., Bosi, A., Hungria, V., Cavo, M., Lee, J. J., Nooka, A. K., Quach, H., Lee, C., Barreto, W., Corradini, P., Min, C. K., Scott, E. C. & 17 othersChanan-Khan, A. A., Horvath, N., Capra, M., Beksac, M., Ovilla, R., Jo, J. C., Shin, H. J., Sonneveld, P., Soong, D., Casneuf, T., Chiu, C., Amin, H., Qi, M., Thiyagarajah, P., Sasser, A. K., Schecter, J. M. & Mateos, M. V., 30 Nov 2018, In : Haematologica: the hematology journal. 103, 12, p. 2079-2087 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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DCEP as a bridge to ongoing therapies for advanced relapsed and/or refractory multiple myeloma

Yuen, H. L. A., Low, M. S. Y., Fedele, P., Kalff, A., Walker, P., Bergin, K., Coutsouvelis, J., Grigoriadis, G. & Spencer, A., 5 Apr 2018, (Accepted/In press) In : Leukemia and Lymphoma. 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits

Yang, S. W., Ku, K. C., Chen, S. Y., Kuo, S. M., Chen, I. F., Wang, T. Y. & Chang, S. J., 1 Jan 2018, In : Journal of Biomaterials Applications. 32, 6, p. 800-812 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Dimeric FcγR ectodomains detect pathogenic anti-platelet factor 4–heparin antibodies in heparin-induced thromobocytopenia

Wines, B. D., Tan, C. W., Duncan, E., McRae, S., Baker, R. I., Andrews, R. K., Esparon, S., Gardiner, E. E. & Hogarth, P. M., 1 Dec 2018, In : Journal of Thrombosis and Haemostasis. 16, 12, p. 2520-2525 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Direct Oral Anticoagulants and the Paradigm Shift in the Management of Venous Thromboembolism

Lim, H. Y., Nandurkar, H. & Ho, P., 1 Apr 2018, In : Seminars in Thrombosis and Hemostasis. 44, 3, p. 261-266 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Dissecting causes for improved survival among patients with acute myeloid leukemia in two different eras receiving identical regimens in sequential randomized studies

Tiong, I. S., Reynolds, J., Bradstock, K. F., Seymour, J. F., Wei, A. H. & on behalf of the Australasian Leukaemia & Lymphoma Group, 22 Aug 2018, In : Blood Cancer Journal. 8, 9, 5 p., 84.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Elastomeric microvalve geometry affects haemocompatibility

Szydzik, C., Brazilek, R. J., Khoshmanesh, K., Akbaridoust, F., Knoerzer, M., Thurgood, P., Muir, I., Marusic, I., Nandurkar, H., Mitchell, A. & Nesbitt, W. S., 1 Jan 2018, In : Lab on a Chip. 18, 12, p. 1778-1792 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

Teh, T. C., Nguyen, N. Y., Moujalled, D. M., Segal, D., Pomilio, G., Rijal, S., Jabbour, A., Cummins, K., Lackovic, K., Blombery, P., Thompson, E., Ekert, P. G., Lessene, G., Glaser, S. P., Huang, D. C. S., Roberts, A. W., Guthridge, M. A. & Wei, A. H., 1 Feb 2018, In : Leukemia. 32, 2, p. 303-312 10 p.

Research output: Contribution to journalArticleResearchpeer-review

EPHB2 regulates platelet activation

Berndt, M. C. & Andrews, R. K., 8 Nov 2018, In : Blood. 132, 19, p. 2002-2004 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

EPO does not promote interaction between the erythropoietin and beta-common receptors

Cheung Tung Shing, K. S., Broughton, S. E., Nero, T. L., Gillinder, K., Ilsley, M. D., Ramshaw, H., Lopez, A. F., Griffin, M. D. W., Parker, M. W., Perkins, A. C. & Dhagat, U., 1 Dec 2018, In : Scientific Reports. 8, 1, 16 p., 12457.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity

Tremblay, C. S., Huang, F. F., Lévesque, G. & Carreau, M., 20 Feb 2018, In : BMC Research Notes. 11, 1, 7 p., 138.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Haemostasis and innate immunity – a complementary relationship: A review of the intricate relationship between coagulation and complement pathways

Keragala, C. B., Draxler, D. F., McQuilten, Z. K. & Medcalf, R. L., 1 Mar 2018, In : British Journal of Haematology. 180, 6, p. 782-798 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Hhex induces promyelocyte self-renewal and cooperates with growth factor independence to cause myeloid leukemia in mice

Jackson, J. T., Ng, A., Shields, B. J., Haupt, S. M., Haupt, Y. & McCormack, M. P., 27 Feb 2018, In : Blood Advances. 2, 4, p. 347-360 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Ibrutinib as treatment for patients with relapsed/refractory follicular lymphoma: Results from the open-label, multicenter, phase II DAWN study

Gopal, A. K., Schuster, S. J., Fowler, N. H., Trotman, J., Hess, G., Hou, J. Z., Yacoub, A., Lill, M., Martin, P., Vitolo, U., Spencer, A., Radford, J., Jurczak, W., Morton, J., Caballero, D., Deshpande, S., Gartenberg, G. J., Wang, S. S., Damle, R. N., Schaffer, M. & 4 othersBalasubramanian, S., Vermeulen, J., Cheson, B. D. & Salles, G., 10 Aug 2018, In : Journal of Clinical Oncology. 36, 23, p. 2405-2412 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Impact of a spleen registry on optimal post-splenectomy vaccination and care

Luu, S., Dendle, C., Jones, P., Ojaimi, S. & Woolley, I. J., 1 Jan 2018, (Accepted/In press) In : Human Vaccines & Immunotherapeutics. p. 1-6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

Conway, J. R. W., Warren, S. C., Herrmann, D., Murphy, K. J., Cazet, A. S., Vennin, C., Shearer, R. F., Killen, M. J., Magenau, A., Mélénec, P., Pinese, M., Nobis, M., Zaratzian, A., Boulghourjian, A., Da Silva, A. M., del Monte-Nieto, G., Adam, A. S. A., Harvey, R. P., Haigh, J. J., Wang, Y. & 6 othersCroucher, D. R., Sansom, O. J., Pajic, M., Caldon, C. E., Morton, J. P. & Timpson, P., 12 Jun 2018, In : Cell Reports. 23, 11, p. 3312-3326 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Investigation of the variable In(Lu) phenotype caused by KLF1 variants

Fraser, N. S., Knauth, C. M., Schoeman, E. M., Moussa, A., Perkins, A. C., Walsh, T., Millard, G. M., Dean, M. M., Hyland, C. A. & Flower, R. L., 1 Oct 2018, In : Transfusion. 58, 10, p. 2414-2420 7 p.

Research output: Contribution to journalArticleResearchpeer-review

KLF1 Acts As a Pioneer Transcription Factor to Open Chromatin and Facilitate Recruitment of GATA1

Gillinder, K. R., Magor, G., Bell, C. C., Ilsley, M. D., Huang, S. & Perkins, A. C., 21 Nov 2018, In : Blood. 132, Suppl 1, p. 501-501 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

KRAS-mutated myeloma cells’ adaptation to glutamine-deprived conditions is linked to autophagy and macropinocytosis

Masoumi Moghaddam, S., Carmichael, I. & Spencer, A., Oct 2018. 1 p.

Research output: Contribution to conferenceAbstractOther

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Kraakman, M. J., Kammoun, H. L., Dragoljevic, D., Al-Sharea, A., Lee, M. K. S., Flynn, M. C., Stolz, C. J., Guirguis, A. A., Lancaster, G. I., Chin-Dusting, J., Curtis, D. J. & Murphy, A. J., 23 Mar 2018, In : Haematologica: the hematology journal. 103, 4, p. 597-606 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

Goldie, S. J., Cottle, D. L., Tan, F. H., Roslan, S., Srivastava, S., Brady, R., Partridge, D. D., Auden, A., Smyth, I. M., Jane, S. M., Dworkin, S. & Darido, C., 19 Oct 2018, In : Cell death & disease. 9, 11, 12 p., 1072.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging

Bonnard, T., Jayapadman, A., Putri, J. A., Cui, J., Ju, Y., Carmichael, C., Angelovich, T. A., Cody, S. H., French, S., Pascaud, K., Pearce, H. A., Jagdale, S., Caruso, F. & Hagemeyer, C. E., 24 Jul 2018, In : ACS Nano. 12, 7, p. 6988-6996 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Macropinocytosis: an important route of tumor nutrient uptake in KRAS-mutated myeloma cells

Masoumi Moghaddam, S. & Spencer, A., Sep 2018, p. 51. 1 p.

Research output: Contribution to conferencePosterOther

Magnetic fibrinolysis: putting the therapeutic wheels in a corkscrew motion

Medcalf, R. L., Hagemeyer, C. E. & Alt, K., 1 Apr 2018, In : Journal of Thrombosis and Haemostasis. 16, 4, p. 615-617 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Maintenance Treatment and Survival in Patients with Myeloma: A Systematic Review and Network Meta-analysis

Gay, F., Jackson, G., Rosiñol, L., Holstein, S. A., Moreau, P., Spada, S., Davies, F., Lahuerta, J. J., Leleu, X., Bringhen, S., Evangelista, A., Hulin, C., Panzani, U., Cairns, D. A., Di Raimondo, F., Macro, M., Liberati, A. M., Pawlyn, C., Offidani, M., Spencer, A. & 11 othersHájek, R., Terpos, E., Morgan, G. J., Bladé, J., Sonneveld, P., San-Miguel, J., McCarthy, P. L., Ludwig, H., Boccadoro, M., Mateos, M. V. & Attal, M., 1 Oct 2018, In : JAMA Oncology. 4, 10, p. 1389-1397 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Mechanisms of Platelet Dysfunction in Patients with Implantable Devices

Casan, J., Andrews, R. K., Gardiner, E. E. & Davis, A. K., 1 Feb 2018, In : Seminars in Thrombosis and Hemostasis. 44, 1, p. 12-19 8 p.

Research output: Contribution to journalArticleOtherpeer-review

Mechanisms of receptor shedding in platelets

Montague, S. J., Andrews, R. K. & Gardiner, E. E., 13 Dec 2018, In : Blood. 132, 24, p. 2535-2545 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia

Brown, F. C., Still, E., Koche, R. P., Yim, C. Y., Takao, S., Cifani, P., Reed, C., Gunasekera, S., Ficarro, S. B., Romanienko, P., Mark, W., McCarthy, C., de Stanchina, E., Gonen, M., Seshan, V., Bhola, P., O’Donnell, C., Spitzer, B., Stutzke, C., Lavallée, V. P. & 12 othersHébert, J., Krivtsov, A. V., Melnick, A., Paietta, E. M., Tallman, M. S., Letai, A., Sauvageau, G., Pouliot, G., Levine, R., Marto, J. A., Armstrong, S. A. & Kentsis, A., 1 Apr 2018, In : Cancer Discovery. 8, 4, p. 478-497 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Mining the plasma cell transcriptome for novel cell surface proteins

Trezise, S., Karnowski, A., Fedele, P. L., Mithraprabhu, S., Liao, Y., D’costa, K., Kueh, A. J., Hardy, M. P., Owczarek, C. M., Herold, M. J., Spencer, A., Shi, W., Willis, S. N., Nutt, S. L. & Corcoran, L. M., 1 Aug 2018, In : International Journal of Molecular Sciences. 19, 8, 2161.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Molecular Patterns of Response and Outcome in the Chemotherapy and Venetoclax in Elderly AML Trial (CAVEAT) study. Blood 2018 132:333

Wei, A., Chua, C. C., Tiong, I. S., Fong, C. Y., Ting, S. B. N., Macraild, S., Salmon, J. M., Ivey, A., Nguyen, J., Yuen, F., Fleming, S. A., Bohlander, S., Reynolds, J. & Roberts, A. W., Dec 2018.

Research output: Contribution to conferenceAbstractOtherpeer-review

Open Access

Monitoring the pulse of thrombus formation: Comment on “Modeling thrombosis in silico: Frontiers, challenges, unresolved problems and milestones” by A.V. Belyaev et al.

Andrews, R. K. & Gardiner, E. E., 1 Nov 2018, In : Physics of Life Reviews. 26-27, p. 113-115 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis

Nébor, D., Graber, J. H., Ciciotte, S. L., Robledo, R. F., Papoin, J., Hartman, E., Gillinder, K. R., Perkins, A. C., Bieker, J. J., Blanc, L. & Peters, L. L., 1 Dec 2018, In : Scientific Reports. 8, 1, 15 p., 12793.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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NLRP3 regulates platelet integrin ±IIbβ3 outside-in signaling, hemostasis and arterial thrombosis

Qiao, J., Wu, X., Luo, Q., Wei, G., Xu, M., Wu, Y., Liu, Y., Li, X., Zi, J., Ju, W., Fu, L., Chen, C., Wu, Q., Zhu, S., Qi, K., Li, D., Li, Z., Andrews, R. K., Zeng, L., Gardiner, E. E. & 1 othersXu, K., 31 Aug 2018, In : Haematologica: the hematology journal. 103, 9, p. 1568-1576 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Perinatal lethality of Par4–/– mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function

French, S. L. & Hamilton, J. R., 17 Feb 2018, In : Platelets. 29, 2, p. 196-198 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Phase Ib study of the mTOR inhibitor everolimus with low dose cytarabine in elderly acute myeloid leukemia

Tiong, I. S., Tan, P., McManus, J., Cummings, N., Sadawarte, S., Catalano, J., Hills, R. & Wei, A., 2018, In : Leukemia and Lymphoma. 59, 2, p. 493-496 4 p.

Research output: Contribution to journalLetterResearchpeer-review

Platelet-targeted dual pathway antithrombotic inhibits thrombosis with preserved hemostasis

Hanjaya-Putra, D., Haller, C., Wang, X., Dai, E., Lim, B., Liu, L., Jaminet, P., Yao, J., Searle, A., Bonnard, T., Hagemeyer, C. E., Peter, K. & Chaikof, E. L., 9 Aug 2018, In : JCI Insight. 3, 15, p. 1-18 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray

Gujar, H., Liang, J. W., Wong, N. C. & Mozhui, K., 1 Mar 2018, In : PLoS ONE. 13, 3, 18 p., 0193496.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Psammomys obesus: a Natural Diet-Controlled Model for Diabetes and Cardiovascular Diseases

Chaudhary, R., Walder, K. R., Hagemeyer, C. E. & Kanwar, J. R., 1 Sep 2018, In : Current Atherosclerosis Reports. 20, 9, 10 p., 46.

Research output: Contribution to journalReview ArticleResearchpeer-review

Regulation of platelet activation and thrombus formation by reactive oxygen species

Qiao, J., Arthur, J. F., Gardiner, E. E., Andrews, R. K., Zeng, L. & Xu, K., 1 Apr 2018, In : Redox Biology. 14, p. 126-130 5 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access

Resistance to Nutrient Deprivation Via Metabolic Re-Programming As Mechanism of 'Metastasis' Promotion in Multiple Myeloma

Savvidou, I., Khong, T. T. F., Spencer, A., Chen, M., Kalff, A., Masoumi Moghaddam, S., Chandrasekara, S. & Brown, A., Dec 2018.

Research output: Contribution to conferenceAbstractOtherpeer-review

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Tremblay, C., Saw, J., Chiu, S. K., Wong, N. C., Tsyganov, K., Ghotb, S., Graham, A. N., Yan, F., Guirguis, A., Sonderegger, S., Lee, N., Kalitsis, P., Reynolds, J., Ting, S., Powell, D., Jane, S. & Curtis, D., 1 Dec 2018, In : Nature Communications. 9, 1, 13 p., 3535.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Self-Assembled Metal–Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles

Besford, Q. A., Ju, Y., Wang, T. Y., Yun, G., Cherepanov, P. V., Hagemeyer, C. E., Cavalieri, F. & Caruso, F., 27 Sep 2018, In : Small. 14, 39, 9 p., 1802342.

Research output: Contribution to journalArticleResearchpeer-review