Research Output 1988 2019

2019

A comparison of global coagulation assays between normal controls and patients with thrombocytopenia

Lim, H. Y., Leung, P., Manitta, V., Nandurkar, H. & Ho, P., 1 Apr 2019, In : International Journal of Laboratory Hematology. 41, 2, p. 184-191 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A comparison of the efficacy of immunomodulatory-free regimens in relapsed or refractory multiple myeloma: a network meta-analysis

Weisel, K., Sonneveld, P., Spencer, A., Beksac, M., Rizzo, M., Xu, Y., Fahrbach, K., Gaudig, M., Slavcev, M., Dearden, L. & Lam, A., 1 Jan 2019, In : Leukemia and Lymphoma. 60, 19, p. 151–162 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A review of global coagulation assays — Is there a role in thrombosis risk prediction?

Lim, H. Y., O'Malley, C., Donnan, G., Nandurkar, H. & Ho, P., 1 Jul 2019, In : Thrombosis Research. 179, p. 45-55 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Autologous platelet-rich plasma for healing chronic venous leg ulcers: Clinical efficacy and potential mechanisms

Weller, C. D., Gardiner, E. E., Arthur, J. F., Southey, M. & Andrews, R. K., Jun 2019, In : International Wound Journal. 16, 3, p. 788-792 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Combining BH3-Mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia

Moujalled, D. M., Pomilio, G., Ghiurau, C., Ivey, A., Salmon, J., Rijal, S., Macraild, S., Zhang, L., Teh, T. C., Tiong, I. S., Lan, P., Chanrion, M., Claperon, A., Rocchetti, F., Zichi, A., Kraus-Berthier, L., Wang, Y., Halilovic, E., Morris, E., Colland, F. & 7 othersSegal, D., Huang, D., Roberts, A. W., Maragno, A. L., Lessene, G., Geneste, O. & Wei, A. H., 1 Apr 2019, In : Leukemia. 33, a, p. 905-917 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

Genetic Variants Within the Erythroid Transcription Factor, KLF1, and Reduction of the Expression of Lutheran and Other Blood Group Antigens: Review of the In(Lu)Phenotype

Fraser, N. S., Knauth, C. M., Moussa, A., Dean, M. M., Hyland, C. A., Perkins, A. C., Flower, R. L. & Schoeman, E. M., 1 Apr 2019, In : Transfusion Medicine Reviews. 33, 2, p. 111-117 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., Carmichael, C. L., Masih, K. E., Morris, S. M., Lindsley, R. C., Janke, L. J., Alexander, T. B., Song, G., Qu, C., Li, Y., Payne-Turner, D., Tomizawa, D., Kiyokawa, N., Valentine, M., Valentine, V. & 28 othersBasso, G., Locatelli, F., Enemark, E. J., Kham, S. K. Y., Yeoh, A. E. J., Ma, X., Zhou, X., Sioson, E., Rusch, M., Ries, R. E., Stieglitz, E., Hunger, S. P., Wei, A. H., To, L. B., Lewis, I. D., D’Andrea, R. J., Kile, B. T., Brown, A. L., Scott, H. S., Hahn, C. N., Marlton, P., Pei, D., Cheng, C., Loh, M. L., Ebert, B. L., Meshinchi, S., Haferlach, T. & Mullighan, C. G., Apr 2019, In : Nature Genetics. 51, 4, p. 694-704 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Hemopoietic Cell Kinase amplification with Protein Tyrosine Phosphatase Receptor T depletion leads to polycythemia, aberrant marrow erythoid maturation, and splenomegaly

Ku, M., MacKinnon, R. N., Wall, M., Narayan, N., Walkley, C., Cheng, H. C., Campbell, L. J., Purton, L. E. & Nandurkar, H., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 7050.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria

Hortle, E., Starrs, L., Brown, F., Jane, S., Curtis, D., McMorran, B. J., Foote, S. J. & Burgio, G., 1 Dec 2019, In : Scientific Reports. 9, 1, 11 p., 6356.

Research output: Contribution to journalArticleResearchpeer-review

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New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous thromboembolism

Tran, H., Gibbs, H., Merriman, E. G., Curnow, J., Young, L., Bennett, A., Tan, C. W., Chunilal, S., Ward, C., Baker, R. I. & Nandurkar, H. H., 1 Mar 2019, In : Medical Journal of Australia. 210, 5, p. 227-235 9 p.

Research output: Contribution to journalArticleOtherpeer-review

PHF6 regulates hematopoietic stem and progenitor cells and its loss synergizes with expression of TLX3 to cause leukemia

McRae, H. M., Garnham, A. L., Hu, Y., Witkowski, M. T., Corbett, M. A., Dixon, M. P., May, R. E., Sheikh, B. N., Chiang, W., Kueh, A. J., Nguyen, T. A., Man, K., Gloury, R., Aubrey, B. J., Policheni, A., Di Rago, L., Alexander, W. S., Gray, D. H. D., Strasser, A., Hawkins, E. D. & 7 othersWilcox, S., Gécz, J., Kallies, A., McCormack, M. P., Smyth, G. K., Voss, A. K. & Thomas, T., 18 Apr 2019, In : Blood. 133, 16, p. 1729-1741 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Platelet Ubiquitylation - It's Everywhere

Gardiner, E. E. & Andrews, R. K., 1 Jan 2019, In : Thrombosis and Haemostasis. 119, 1, p. 6-8 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Targeting CD39 Toward Activated Platelets Reduces Systemic Inflammation and Improves Survival in Sepsis: A Preclinical Pilot Study

Granja, T., Körner, A., Glück, C., Hohmann, J. D., Wang, X., Köhler, D., Streißenberger, A., Nandurkar, H. H., Mirakaj, V., Rosenberger, P., Peter, K. & Straub, A., 1 May 2019, In : Critical Care Medicine. 47, 5, p. e420-e427 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The mode of anesthesia influences outcome in mouse models of arterial thrombosis

Sashindranath, M., Sturgeon, S., French, S. L., Craenmehr, D. D. D., Selan, C., Freddi, S., Johnson, C., Cody, S., Nesbitt, W., Hamilton, J., Cody, S. H., Nesbitt, W., Hamilton, J. & Nandurkar, H., Apr 2019, In : Thrombosis and Haemostasis. 3, 2, p. 197-206 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1

Shields, B. J., Slape, C. I., Vo, N., Jackson, J. T., Pliego-Zamora, A., Ranasinghe, H., Shi, W., Curtis, D. J. & McCormack, M. P., 1 Jan 2019, In : Leukemia. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, Y. D., Yu, L., Ying, L., Balic, J., Gao, H., Deng, N. T., West, A., Yan, F., Ji, C. B., Gough, D., Tan, P., Jenkins, B. J. & Li, J. K., 1 Jan 2019, (Accepted/In press) In : International Journal of Cancer. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury

Tan, X. L., Sun, M., Brady, R. D., Liu, S., Llanos, R. M., Cheung, S., Wright, D. K., Casillas-Espinosa, P. M., Sashindranath, M., O'Brien, T. J., McDonald, S. J., Turner, B. J. & Shultz, S., 1 Jan 2019, In : Journal of Neurotrauma. 36, 1, p. 87-99 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Chopin, M., Lun, A. T., Zhan, Y., Schreuder, J., Coughlan, H., D'Amico, A., Mielke, L. A., Almeida, F. F., Kueh, A. J., Dickins, R. A., Belz, G. T., Naik, S. H., Lew, A. M., Bouillet, P., Herold, M. J., Smyth, G. K., Corcoran, L. M. & Nutt, S. L., 15 Jan 2019, In : Immunity. 50, 1, p. 77-90.e5 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Utility of a Nurse-Led Pathway for Patients with Acute Venous Thromboembolism Discharged on Rivaroxaban: A Prospective Cohort Study

Lim, M. S., Indran, T., Cummins, A., Bennett, A., Wood, E., Brown, S., McQuilten, Z., Tran, H., Chan, N. C. & Chunilal, S., 2019, In : Seminars in Thrombosis and Hemostasis. 45, 2, p. 187-195 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2018

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant

French, S. L., Thalmann, C., Bray, P. F., Macdonald, L. E., Murphy, A. J., Sleeman, M. W. & Hamilton, J. R., 12 Jun 2018, In : Blood Advances. 2, 11, p. 1283-1293 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8

Bouhy, D., Juneja, M., Katona, I., Holmgren, A., Asselbergh, B., De Winter, V., Hochepied, T., Goossens, S., Haigh, J. J., Libert, C., Ceuterick-de Groote, C., Irobi, J., Weis, J. & Timmerman, V., Jan 2018, In : Acta Neuropathologica. 135, 1, p. 131–148 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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AMG 176, a selective MCL1 inhibitor, is effective in hematologic cancer models alone and in combination with established therapies

Caenepeel, S., Brown, S. P., Belmontes, B., Moody, G., Keegan, K. S., Chui, D., Whittington, D. A., Huang, X., Poppe, L., Cheng, A. C., Cardozo, M., Houze, J., Li, Y., Lucas, B., Paras, N. A., Wang, X., Taygerly, J. P., Vimolratana, M., Zancanella, M., Zhu, L. & 18 othersCajulis, E., Osgood, T., Sun, J., Damon, L., Egan, R. K., Greninger, P., McClanaghan, J. D., Gong, J., Moujalled, D., Pomilio, G., Beltran, P., Benes, C. H., Roberts, A. W., Huang, D. C., Wei, A., Canon, J., Coxon, A. & Hughes, P. E., 1 Dec 2018, In : Cancer Discovery. 8, 12, p. 1582-1597 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Analysis of circulating tumor DNA

Mithraprabhu, S. & Spencer, A., 1 Jan 2018, Methods in Molecular Biology. Humana Press, p. 129-145 17 p. (Methods in Molecular Biology; vol. 1792).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Analysis of histone modifications in acute myeloid leukaemia using chromatin immunoprecipitation

Shields, B. J., Keniry, A., Blewitt, M. E. & McCormack, M. P., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York : Humana Press, p. 177-184 8 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

An evaluation of global coagulation assays in myeloproliferative neoplasm

Lim, H. Y., Ng, C., Rigano, J., Tacey, M. A., Donnan, G., Nandurkar, H. H. & Ho, P. W. S., 1 Apr 2018, In : Blood Coagulation and Fibrinolysis. 29, 3, p. 300-306 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel role for Lyl1 in primitive erythropoiesis

Chiu, S. K., Saw, J. M. Y., Huang, Y., Sonderegger, S. E., Wong, N. C. L., Powell, D. R., Beck, D., Pimanda, J., Tremblay, C. & Curtis, D. J., 11 Oct 2018, In : Development. 145, 19, 9 p., dev162990.

Research output: Contribution to journalArticleResearchpeer-review

A phase 1 clinical trial evaluating marizomib, pomalidomide and low-dose dexamethasone in relapsed and refractory multiple myeloma (NPI-0052-107): final study results

Spencer, A., Harrison, S., Zonder, J., Badros, A., Laubach, J., Bergin, K., Khot, A., Zimmerman, T., Chauhan, D., Levin, N., MacLaren, A., Reich, S. D., Trikha, M. & Richardson, P., 1 Jan 2018, In : British Journal of Haematology. 180, 1, p. 41-51 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

Ziegler, M., Hohmann, J. D., Searle, A. K., Abraham, M-K., Nandurkar, H. H. & Wang, X., 7 Jan 2018, In : European Heart Journal. 39, 2, p. 111-116 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Author Correction: Metabolic gatekeeper function of B-lymphoid transcription factors (Nature (2017) DOI: 10.1038/nature21076)

Chan, L. N., Chen, Z., Braas, D., Lee, J. W., Xiao, G., Geng, H., Cosgun, K. N., Hurtz, C., Shojaee, S., Cazzaniga, V., Schjerven, H., Ernst, T., Hochhaus, A., Kornblau, S. M., Konopleva, M., Pufall, M. A., Cazzaniga, G., Liu, G. J., Milne, T. A., Koeffler, H. P. & 7 othersRoss, T. S., Sánchez-García, I., Borkhardt, A., Yamamoto, K. R., Dickins, R. A., Graeber, T. G. & Müschen, M., 28 Jun 2018, In : Nature. 558, 7711, p. E5 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Autoregulation of von Willebrand factor function by a disulfide bond switch

Butera, D., Passam, F., Ju, L., Cook, K. M., Woon, H., Aponte-Santamaría, C., Gardiner, E., Davis, A. K., Murphy, D. A., Bronowska, A., Luken, B. M., Baldauf, C., Jackson, S., Andrews, R., Gräter, F. & Hogg, P. J., 28 Feb 2018, In : Science advances. 4, 2, 13 p., eaaq1477.

Research output: Contribution to journalArticleResearchpeer-review

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Bone marrow defects and platelet function: A focus on MDS and CLL

Luu, S., Gardiner, E. E. & Andrews, R. K., 1 May 2018, In : Cancers. 10, 5, 10 p., 147.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

Conway, A., Brown, F. C., Hortle, E. J., Burgio, G., Foote, S. J., Morton, C. J., Jane, S. M. & Curtis, D. J., 21 May 2018, In : Disease Models and Mechanisms. 11, 5, 8 p., dmm034678.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Carfilzomib–dexamethasone versus subcutaneous or intravenous bortezomib in relapsed or refractory multiple myeloma: secondary analysis of the phase 3 ENDEAVOR study

Goldschmidt, H., Moreau, P., Ludwig, H., Niesvizky, R., Chng, W. J., Joshua, D., Weisel, K., Spencer, A., Orlowski, R. Z., Feng, S., Iskander, K. S. & Dimopoulos, M. A., 2018, In : Leukemia and Lymphoma. 59, 6, p. 1364-1374 11 p.

Research output: Contribution to journalArticleResearchpeer-review

CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages

Samudra, A. N., Dwyer, K. M., Selan, C., Freddi, S., Murray-Segal, L., Nikpour, M., Hickey, M. J., Peter, K., Robson, S. C., Sashindranath, M., Cowan, P. J. & Nandurkar, H. H., Mar 2018, In : Journal of Autoimmunity. 88, p. 131-138 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Tfrc-mutant mice with microcytic phenotypes

Conway, A. J., Brown, F. C., Rank, G., Kile, B. T., Morton, C. J., Jane, S. M. & Curtis, D. J., 14 Aug 2018, In : Blood Advances. 2, 5, p. 1914-1922 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Compression force sensing regulates integrin αiIbβ3 adhesive function on diabetic platelets

Ju, L., McFadyen, J. D., Al-Daher, S., Alwis, I., Chen, Y., Tønnesen, L. L., Maiocchi, S., Coulter, B., Calkin, A. C., Felner, E. I., Cohen, N., Yuan, Y., Schoenwaelder, S. M., Cooper, M. E., Zhu, C. & Jackson, S. P., 1 Dec 2018, In : Nature Communications. 9, 1, 16 p., 1087.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Considerations for pre-transfusion immunohaematology testing in patients receiving the anti-CD38 monoclonal antibody daratumumab for the treatment of multiple myeloma

Quach, H., Benson, S., Haysom, H., Wilkes, A. M., Zacher, N., Cole-Sinclair, M., Miles Prince, H., Mollee, P., Spencer, A., Joy Ho, P., Harrison, S. J., Lee, C., Augustson, B. & Daly, J., 1 Feb 2018, In : Internal Medicine Journal. 48, 2, p. 210-220 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Open Access
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Current and future antiplatelet therapies: Emphasis on preserving haemostasis

McFadyen, J. D., Schaff, M. & Peter, K., 1 Mar 2018, In : Nature Reviews Cardiology. 15, 3, p. 181-191 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma: Updated analysis of CASTOR

Spencer, A., Lentzsch, S., Weisel, K., Avet-Loiseau, H., Mark, T. M., Spicka, I., Masszi, T., Lauri, B., Levin, M. D., Bosi, A., Hungria, V., Cavo, M., Lee, J. J., Nooka, A. K., Quach, H., Lee, C., Barreto, W., Corradini, P., Min, C. K., Scott, E. C. & 17 othersChanan-Khan, A. A., Horvath, N., Capra, M., Beksac, M., Ovilla, R., Jo, J. C., Shin, H. J., Sonneveld, P., Soong, D., Casneuf, T., Chiu, C., Amin, H., Qi, M., Thiyagarajah, P., Sasser, A. K., Schecter, J. M. & Mateos, M. V., 30 Nov 2018, In : Haematologica: the hematology journal. 103, 12, p. 2079-2087 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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DCEP as a bridge to ongoing therapies for advanced relapsed and/or refractory multiple myeloma

Yuen, H. L. A., Low, M. S. Y., Fedele, P., Kalff, A., Walker, P., Bergin, K., Coutsouvelis, J., Grigoriadis, G. & Spencer, A., 5 Apr 2018, (Accepted/In press) In : Leukemia and Lymphoma. 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits

Yang, S. W., Ku, K. C., Chen, S. Y., Kuo, S. M., Chen, I. F., Wang, T. Y. & Chang, S. J., 1 Jan 2018, In : Journal of Biomaterials Applications. 32, 6, p. 800-812 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Dimeric FcγR ectodomains detect pathogenic anti-platelet factor 4–heparin antibodies in heparin-induced thromobocytopenia

Wines, B. D., Tan, C. W., Duncan, E., McRae, S., Baker, R. I., Andrews, R. K., Esparon, S., Gardiner, E. E. & Hogarth, P. M., 1 Dec 2018, In : Journal of Thrombosis and Haemostasis. 16, 12, p. 2520-2525 6 p.

Research output: Contribution to journalArticleResearchpeer-review

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Direct Oral Anticoagulants and the Paradigm Shift in the Management of Venous Thromboembolism

Lim, H. Y., Nandurkar, H. & Ho, P., 1 Apr 2018, In : Seminars in Thrombosis and Hemostasis. 44, 3, p. 261-266 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Dissecting causes for improved survival among patients with acute myeloid leukemia in two different eras receiving identical regimens in sequential randomized studies

Tiong, I. S., Reynolds, J., Bradstock, K. F., Seymour, J. F., Wei, A. H. & on behalf of the Australasian Leukaemia & Lymphoma Group, 22 Aug 2018, In : Blood Cancer Journal. 8, 9, 5 p., 84.

Research output: Contribution to journalArticleResearchpeer-review

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Elastomeric microvalve geometry affects haemocompatibility

Szydzik, C., Brazilek, R. J., Khoshmanesh, K., Akbaridoust, F., Knoerzer, M., Thurgood, P., Muir, I., Marusic, I., Nandurkar, H., Mitchell, A. & Nesbitt, W. S., 1 Jan 2018, In : Lab on a Chip. 18, 12, p. 1778-1792 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

Teh, T. C., Nguyen, N. Y., Moujalled, D. M., Segal, D., Pomilio, G., Rijal, S., Jabbour, A., Cummins, K., Lackovic, K., Blombery, P., Thompson, E., Ekert, P. G., Lessene, G., Glaser, S. P., Huang, D. C. S., Roberts, A. W., Guthridge, M. A. & Wei, A. H., 1 Feb 2018, In : Leukemia. 32, 2, p. 303-312 10 p.

Research output: Contribution to journalArticleResearchpeer-review

EPHB2 regulates platelet activation

Berndt, M. C. & Andrews, R. K., 8 Nov 2018, In : Blood. 132, 19, p. 2002-2004 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review