Anatomy & Developmental Biology

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2017

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

Taylor, R. A., Fraser, M., Livingstone, J., Espiritu, S. M. G., Thorne, H., Huang, V., Lo, W., Shiah, Y-J., Yamaguchi, T. N., Sliwinski, A., Horsburgh, S., Meng, A., Heisler, L. E., Yu, N., Yousif, F., Papargiris, M., Lawrence, M. G., Timms, L., Murphy, D. G., Frydenberg, M. & 8 othersHopkins, J. F., Bolton, D., Clouston, D., McPherson, J. D., Van Der Kwast, T., Boutros, P. C., Risbridger, G. P. & Bristow, R. G., 9 Jan 2017, In : Nature Communications. 8, 10 p., 13671.

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Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes

Chan, A. L., La, H. M., Legrand, J. M. D., Mäkelä, J. A., Eichenlaub, M., De Seram, M., Ramialison, M. & Hobbs, R. M., 12 Sep 2017, In : Stem Cell Reports. 9, 3, p. 956-971 16 p.

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Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Marino, E., Richards, J. L., McLeod, K. H., Stanley, D., Yap, Y. A., Knight, J., McKenzie, C., Kranich, J., Oliveira, A. C., Rossello, F. J., Krishnamurthy, B., Nefzger, C. M., Macia, L., Thorburn, A., Baxter, A. G., Morahan, G., Wong, L. H., Polo, J. M., Moore, R. J., Lockett, T. J. & 4 othersClarke, J. M., Topping, D. L., Harrison, L. C. & Mackay, C. R., May 2017, In : Nature Immunology. 18, 5, p. 552-562 13 p.

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Hormonal regulation of platypus Beta-lactoglobulin and monotreme lactation protein genes

Enjapoori, A. K., Lefevre, C. M., Nicholas, K. R. & Sharp, J. A., 1 Feb 2017, In : General and Comparative Endocrinology. 242, p. 38-48 11 p.

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Human milk bioactivity: lessons from the evolution of lactation

Sharp, J., Watt, A., Lefèvre, C. & Nicholas, K., Apr 2017, In : Australian Biochemist. 48, 1, p. 13-18 6 p.

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Hyperglycemia is associated with reduced testicular function and activin dysregulation in the Ins2Akita+/- mouse model of type 1 diabetes

Maresch, C. C., Stute, D. C., Ludlow, H., Hammes, H. P., de Kretser, D. M., Hedger, M. P. & Linn, T., 5 May 2017, In : Molecular and Cellular Endocrinology. 446, p. 91-101 11 p.

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Impact of endurance exercise training on adipocyte microRNA expression in overweight men

Tsiloulis, T., Pike, J., Powell, D., Rossello, F. J., Canny, B. J., Meex, R. C. R. & Watt, M. J., Jan 2017, In : FASEB Journal. 31, 1, p. 161-171 11 p.

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Induction of EAO in mice: responses to 2 elevated circulating levels of the activin-binding protein, follistatin

Nicholas, N., Muir, J. A., Hayward, S., Chen, J. L., Stanton, P. G., Gregorevic, P., de Kretser, D. M., Loveland, K. L., Bhushan, S., Meinhardt, A., Fijak, M. & Hedger, M. P., 1 Sep 2017, In : Reproduction. 154, 3, p. 293-305 13 p.

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Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells

Bellmaine, S. F., Ovchinnikov, D. A., Manallack, D. T., Cuddy, C. E., Elefanty, A. G., Stanley, E. G., Wolvetang, E. J., Williams, S. J. & Pera, M., 8 Sep 2017, In : eLife. 6, 20 p., e24502.

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In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

Rahmoun, M., Lavery, R., Laurent-Chaballier, S., Bellora, N., Philip, G. K., Rossitto, M., Symon, A., Pailhoux, E., Cammas, F., Chung, J., Bagheri-Fam, S., Murphy, M., Bardwell, V. J., Zarkower, D., Boizet-Bonhoure, B., Clair, P., Harley, V. R. & Poulat, F., 7 Jul 2017, In : Nucleic Acids Research. 45, 12, p. 7191-7211 21 p.

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INPP5E regulates phosphoinositide-dependent cilia transition zone function

Dyson, J. M., Conduit, S. E., Feeney, S. J., Hakim, S., DiTommaso, T., Fulcher, A. J., Sriratana, A., Ramm, G., Horan, K. A., Gurung, R., Wicking, C., Smyth, I. & Mitchell, C. A., 2 Jan 2017, In : Journal of Cell Biology. 216, 1, p. 247-263 17 p.

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Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: A feasibility study

Iddawela, M., Rueda, O. M., Eremin, J., Eremin, O., Cowley, J., Earl, H. M. & Caldas, C., 11 Jul 2017, In : BMC Genomics. 18, 1, 13 p., 526.

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Interactome of the inhibitory isoform of the nuclear transporter Importin 13

Fatima, S., Wagstaff, K. M., Lieu, K. G., Davies, R. G., Tanaka, S. S., Yamaguchi, Y. L., Loveland, K. L., Tam, P. P. L. & Jans, D. A., 1 Mar 2017, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 3, p. 546-561 16 p.

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Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice

Winship, A. & Dimitriadis, E., Feb 2017, In : Placenta. 50, p. 99-101 3 p.

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Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice

Winship, A. L., Sorby, K., Correia, J., Rainczuk, A., Yap, J. & Dimitriadis, E., 1 May 2017, In : Placenta. 53, p. 92-100 9 p.

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Intra- and Intersexual swim bladder dimorphisms in the plainfin midshipman fish (Porichthys notatus): Implications of swim bladder proximity to the inner ear for sound pressure detection

Mohr, R. A., Whitchurch, E. A., Anderson, R. D., Forlano, P. M., Fay, R. R., Ketten, D. R., Cox, T. C. & Sisneros, J. A., 1 Nov 2017, In : Journal of Morphology. 278, 11, p. 1458-1468 11 p.

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Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

Menkhorst, E. M., Van Sinderen, M. L., Rainczuk, K., Cuman, C., Winship, A. & Dimitriadis, E., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 8690.

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In vivo bone strain and finite element modeling of a rhesus macaque mandible during mastication

Panagiotopoulou, O., Iriarte-Diaz, J., Wilshin, S., Dechow, P. C., Taylor, A. B., Mehari Abraha, H., Aljunid, S. F. & Ross, C. F., 1 Oct 2017, In : Zoology. 124, p. 13-29 17 p.

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Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

Kryza, T., Silva, L. M., Bock, N., Fuhrman-Luck, R. A., Stephens, C. R., Gao, J., Samaratunga, H., Australian Prostate Cancer BioResource, Lawrence, M. G., Hooper, J. D., Dong, Y., Risbridger, G. P. & Clements, J. A., 1 Oct 2017, In : Molecular Oncology. 11, 10, p. 1307-1329 23 p.

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Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse

Dunleavy, J. E. M., Okuda, H., O’Connor, A. E., Merriner, D. J., O’Donnell, L., Jamsai, D., Bergmann, M. & O’Bryan, M. K., 14 Nov 2017, In : PLoS Genetics. 13, 11, 28 p., e1007078.

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Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death

Hirst, C. S., Stamp, L. A., Bergner, A. J., Hao, M. M., Tran, M., Morgan, J., Dutschmann, M., Allen, A. M., Paxinos, G., Furlong, T., McKeown, S. J. & Young, H. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16676.

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LIN-32/Atonal Controls Oxygen Sensing Neuron Development in Caenorhabditis elegans

Romanos, T. R., Pladevall-Morera, D., Langebeck-Jensen, K., Hansen, S., Ng, L. & Pocock, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 10 p., 7294.

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Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder

Savchenko, E., Singh, Y., Konttinen, H., Lejavova, K., Santos, L. M., Grubman, A., Karkkainen, V., Keksa-Goldsteine, V., Naumenko, N., Tavi, P., White, A. R., Malm, T., Koistinaho, J. & Kanninen, K. M., 1 Sep 2017, In : Disease Models and Mechanisms. 10, 9, p. 1089-1100 12 p.

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Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease

Dudakov, J. A., Mertelsmann, A. M., O’Connor, M. H., Jenq, R. R., Velardi, E., Young, L. F., Smith, O. M., Boyd, R. L., van den Brink, M. R. M. & Hanash, A. M., 17 Aug 2017, In : Blood. 130, 7, p. 933-942 10 p.

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LRGUK1 is part of a multiprotein complex required for manchette function and male fertility

Okuda, H., Deboer, K., O'Connor, A. E., Merriner, D. J., Jamsai, D. & O'Bryan, M. K., 1 Mar 2017, In : FASEB Journal. 31, 3, p. 1141-1152 12 p.

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Macrophage physiology in the eye

Chinnery, H. R., McMenamin, P. G. & Dando, S. J., Apr 2017, In : Pflugers Archiv European Journal of Physiology. 469, 3, p. 501-515 15 p.

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Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model

Tamasas, B. & Cox, T. C., 1 Mar 2017, In : Journal of Dental Research. 96, 3, p. 315-322 8 p.

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MASTL is essential for anaphase entry of proliferating primordial germ cells and establishment of female germ cells in mice

Risal, S., Zhang, J., Adhikari, D., Liu, X., Shao, J., Hu, M., Busayavalasa, K., Tu, Z., Chen, Z., Kaldis, P. & Liu, K., 7 Feb 2017, In : Cell Discovery. 3, 14 p., 16052.

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Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II

Nabti, I., Grimes, R., Sarna, H., Marangos, P. & Carroll, J., 18 May 2017, In : Nature Communications. 8, 9 p., 15346.

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MicroRNA-31 promotes adverse cardiac remodeling and dysfunction in ischemic heart disease

Martinez, E. C., Lilyanna, S., Wang, P., Vardy, L. A., Jiang, X., Armugam, A., Jeyaseelan, K. & Richards, M. A., 1 Nov 2017, In : Journal of Molecular and Cellular Cardiology. 112, p. 27-39 13 p.

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MicroRNAs regulating cluster of differentiation 46 (CD46) in cardioembolic and non-cardioembolic stroke

Tan, J. R., Tan, K. S., Yong, F-L., Armugam, A., Wang, C-W., Jeyaseelan, K. & Wong, P. T. H., 1 Feb 2017, In : PLoS ONE. 12, 2, 16 p., e0172131.

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miR-378 reduces mesangial hypertrophy and kidney tubular fibrosis via MAPK signalling

Wang, B., Yao, K., Wise, A. F., Lau, R., Shen, H-H., Tesch, G. H. & Ricardo, S. D., 2017, In : Clinical Science. 131, 5, p. 411-423 13 p.

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Mouse double minute homologue 2 (MDM2) downregulation by miR-661 impairs human endometrial epithelial cell adhesive capacity

Winship, A., Ton, A., Van Sinderen, M., Menkhorst, E., Rainczuk, K., Griffiths, M., Cuman, C. & Dimitriadis, E., 29 Aug 2017, In : Reproduction, Fertility and Development. 30, p. 477-486 10 p.

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Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment

Shaffer, J. R., Li, J., Lee, M. K., Roosenboom, J., Orlova, E., Adhikari, K., Gallo, C., Poletti, G., Schuler-Faccini, L., Bortolini, M. C., Canizales-Quinteros, S., Rothhammer, F., Bedoya, G., González-José, R., Pfeffer, P. E., Wollenschlaeger, C. A., Hecht, J. T., Wehby, G. L., Moreno, L. M., Ding, A. & 11 othersJin, L., Yang, Y., Carlson, J. C., Leslie, E. J., Feingold, E., Marazita, M. L., Hinds, D. A., Cox, T. C., Wang, S., Ruiz-Linares, A. & Weinberg, S. M., 7 Dec 2017, In : American Journal of Human Genetics. 101, 6, p. 913-924 12 p.

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Muscle Stem Cells Undergo Extensive Clonal Drift during Tissue Growth via Meox1-Mediated Induction of G2 Cell-Cycle Arrest

Nguyen, P. D., Gurevich, D. B., Sonntag, C., Hersey, L., Alaei, S., Nim, H. T., Siegel, A., Hall, T. E., Rossello, F. J., Boyd, S. E., Polo, J. M. & Currie, P. D., 6 Jul 2017, In : Cell Stem Cell. 21, 1, p. 107-119.e6 19 p.

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Mutations in the Katnb1 gene cause left-right asymmetry and heart defects

Furtado, M. B., Merriner, D. J., Berger, S., Rhodes, D., Jamsai, D. & O'Bryan, M. K., Dec 2017, In : Developmental Dynamics. 246, 12, p. 1027-1035 9 p.

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Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related

Hart, J. E., Clarke, I. J., Risbridger, G. P., Ferneyhough, B. & Vega-Hernández, M., 13 Oct 2017, In : PeerJ. 2017, 10, 42 p., e3833.

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Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation

Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J. & Chidgey, A. P., Feb 2017, In : Biomaterials. 118, p. 1-15 15 p., 145253.

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Navβ2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing

Hu, T., Xiao, Z., Mao, R., Chen, B., Lu, M-N., Tong, J., Mei, R., Li, S-S., Xiao, Z., Zhang, L-F. & XiYang, Y-B., 16 Oct 2017, In : Oncotarget. 8, 59, p. 99284-99295 12 p.

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Neural stem cell-conditioned medium suppresses inflammation and promotes spinal cord injury recovery

Cheng, Z., Bosco, D. B., Sun, L., Chen, X., Xu, Y., Tai, W., Didier, R., Li, J., Fan, J., He, X. & Ren, Y., 1 Mar 2017, In : Cell Transplantation: the regenerative medicine journal. 26, 3, p. 469-482 14 p.

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Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia

Yuan, Y., Alwis, I., Wu, M. C. L., Kaplan, Z., Ashworth, K., Bark, D., Pham, A., McFadyen, J., Schoenwaelder, S. M., Josefsson, E. C., Kile, B. T. & Jackson, S. P., 27 Sep 2017, In : Science Translational Medicine. 9, 409, 14 p., eaam5861.

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New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

O'Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T-L., Adams, T. E., Phan, T., Bentley, J. D., McKinstry, W. J., Oliva, K., McMurrick, P. J., Wang, Y-C., Rossello, F. J., Lindeman, G. J., Chen, D., Jarde, T. & 7 othersClark, A. T., Abud, H. E., Visvader, J. E., Nefzger, C. M., Polo, J. M., Loring, J. F. & Laslett, A. L., 1 Mar 2017, In : Stem Cells. 35, 3, p. 626-640 15 p.

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Over-expression of Activin-βC is associated with murine and human prostate disease

Ottley, E. C., Reader, K. L., Lee, K., Marino, F. E., Nicholson, H. D., Risbridger, G. P. & Gold, E., Apr 2017, In : Hormones and Cancer. 8, 2, p. 100-107 8 p.

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Phosphatidylserine save-me signals drive functional recovery of severed axons in Caenorhabditis elegans

Abay, Z. C., Wong, M. Y-Y., Teoh, J-S., Vijayaraghavan, T., Hilliard, M. A. & Neumann, B., 21 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10196-E10205 10 p.

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PLAG1 deficiency impairs spermatogenesis and sperm motility in mice

Juma, A. R., Grommen, S. V. H., O'Bryan, M. K., O'Connor, A. E., Merriner, D. J., Hall, N. E., Doyle, S. R., Damdimopoulou, P. E., Barriga, D., Hart, A. H., Van De Ven, W. J. M. & De Groef, B., 1 Dec 2017, In : Scientific Reports. 7, 1, 12 p., 5317.

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Proportion and difference of neural stem cells and neurons from different embryonic mouse brain tissues

Zhang, F. L., Yang, L. J. & Xiao, Z. C., 28 Jul 2017, In : Chinese Journal of Tissue Engineering Research. 21, 21, p. 3364-3369 6 p.

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Protective effect of let-7 miRNA family in regulating inflammation in diabetes-associated atherosclerosis

Brennan, E. P., Wang, B., McClelland, A., Mohan, M., Marai, M., Beuscart, O., Derouiche, S., Gray, S., Pickering, R., Tikellis, C., De Gaetano, M., Barry, M., Belton, O., Ali-Shah, S. T., Guiry, P., Jandeleit-Dahm, K. A. M., Cooper, M. E., Godson, C. & Kantharidis, P., 1 Aug 2017, In : Diabetes. 66, 8, p. 2266-2277 12 p.

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PTPN2 regulates T cell lineage commitment and αß versus γδ specification

Wiede, F., Dudakov, J. A., Lu, K-H., Dodd, G. T., Butt, T., Godfrey, D. I., Strasser, A., Boyd, R. L. & Tiganis, T., 4 Sep 2017, In : Journal of Experimental Medicine. 214, 9, p. 2733-2758 26 p.

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