Research Output

2017

Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under Xeno-free conditions restore motor deficits in Parkinsonian rodents

Niclis, J. C., Gantner, C. W., Alsanie, W. F., McDougall, S. J., Bye, C. R., Elefanty, A. G., Stanley, E. G., Haynes, J. M., Pouton, C. W., Thompson, L. H. & Parish, C. L., 1 Mar 2017, In : Stem Cells Translational Medicine. 6, 3, p. 937-948 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Endocrinology of the male reproductive system and spermatogenesis

O'Donnell, L., Stanton, P. & de Kretser, D. M., 2017, Endocrinology of Male Reproduction. Feingold, KR., Anawalt, B. & Boyce, A. (eds.). USA: Endotext, p. 1-69 69 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Open Access

Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system

Workman, M. J., Mahe, M. M., Trisno, S., Poling, H. M., Watson, C. L., Sundaram, N., Chang, C. F., Schiesser, J., Aubert, P., Stanley, E. G., Elefanty, A. G., Miyaoka, Y., Mandegar, M. A., Conklin, B. R., Neunlist, M., Brugmann, S. A., Helmrath, M. A. & Wells, J. M., 1 Jan 2017, In : Nature Medicine. 23, 1, p. 49-59 11 p.

Research output: Contribution to journalArticleResearchpeer-review

183 Citations (Scopus)

Erratum to: Human Wharton's Jelly Stem Cells and Its Conditioned Medium Enhance Healing of Excisional and Diabetic Wounds: Human Wharton's Jelly Stem Cells and Wound Healing (Journal of Cellular Biochemistry, (2014), 115, 2, (290-302), 10.1002/jcb.24661)

Fong, C-Y., Tam, K., Cheyyatraivendran, S., Gan, S. U., Gauthaman, K., Arunmozhiarasi, Jeyaseelan, K., Choolani, M., Biswas, A. & Bongso, A., 1 Sep 2017, In : Journal of Cellular Biochemistry. 118, 9, p. 3016 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
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4 Citations (Scopus)

Evaluating behavioral effects on modern human shape tali through GMM

Sorrentino, R., Minghetti, C., Parr, W., Turley, K., Wroe, S., Shaw, C., Saers, J., Su, A., Fiorenza, L., Feletti, F., Frost, S., Carlson, K. J., Belcastro, G. M., Ryan, T. & Benazzi, S., 2017.

Research output: Contribution to conferenceAbstract

Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

Pustovit, R. V., Callaghan, B., Ringuet, M. T., Kerr, N. F., Hunne, B., Smyth, I. M., Pietra, C. & Furness, J. B., 1 Aug 2017, In : Physiological Reports. 5, 15, 11 p., e13385.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)
8 Citations (Scopus)

Exploiting induced senescence in intestinal organoids to drive enteroendocrine cell expansion

Ramsay, R. G. & Abud, H. E., 1 May 2017, In : Stem Cell Investigation. 2017, MAY, 36.

Research output: Contribution to journalReview ArticleOtherpeer-review

1 Citation (Scopus)

Exploring shape variation in modern human tali

Fiorenza, L., Sorrentino, R., Minghetti, C., Parr, W., Turley, K., Wroe, S., Shaw, C., Saers, J., Su, A., Feletti, F., Frost, S., Carlson, K. J., Belcastro, G. M., Ryan, T. & Benazzi, S., 2017, p. 365. 1 p.

Research output: Contribution to conferenceAbstract

Exposure to GDNF enhances the ability of enteric neural progenitors to generate an enteric nervous system

McKeown, S. J., Mohsenipour, M., Bergner, A. J., Young, H. M. & Stamp, L. A., 14 Feb 2017, In : Stem Cell Reports. 8, 2, p. 476-488 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Expression of ciliated bronchial epithelium 1 during human spermatogenesis

Pleuger, C., Fietz, D., Hartmann, K., Schuppe, H. C., Weidner, W., Kliesch, S., Baker, M., O'Bryan, M. K. & Bergmann, M., 1 Jul 2017, In : Fertility and Sterility. 108, 1, p. 47-54 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Expression patterns of HENMT1 and PIWIL1 in human testis: Implications for transposon expression

Hempfling, AL., Lim, SL., Adelson, DL., Evans, J., O'Connor, AE., Qu, ZP., Kliesch, S., Weidner, W., O'Bryan, MK. & Bergmann, M., 1 Oct 2017, In : Reproduction. 154, p. 363-374 12 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Extracerebral dysfunction in animal models of autism spectrum disorder

Hill-Yardin, E. L., McKeown, S. J., Novarino, G. & Grabrucker, A. M., 2017, Translational Anatomy and Cell Biology of Autism Spectrum Disorder. Schmeisser, M. J. & Boeckers, T. M. (eds.). Springer-Verlag London Ltd., Vol. 224. p. 159-187 29 p. (Advances in Anatomy Embryology and Cell Biology; vol. 224).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

1 Citation (Scopus)

Fibronectin-guided migration of carcinoma collectives

Gopal, S., Veracini, L., Grall, D., Butori, C., Schaub, S., Audebert, S., Camoin, L., Baudelet, E., Adwanska, A., Beghelli-De La Forest Divonne, S., Violette, S. M., Weinreb, P. H., Rekima, S., Ilie, M., Sudaka, A., Hofman, P. & Van Obberghen-Schilling, E., 19 Jan 2017, In : Nature Communications. 8, 15 p., 14105.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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54 Citations (Scopus)

Follistatin and the breast implant capsule

Frenkiel, B. A., Temple-Smith, P., Kretser, D. D. & Southwick, G. J., 2017, In : Plastic and Reconstructive Surgery - Global Open. 5, 3, 9 p., 1258.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Follistatin attenuates radiation-induced fibrosis in a murine model

Forrester, H. B., De Kretser, D. M., Leong, T., Hagekyriakou, J. & Sprung, C. N., 1 Mar 2017, In : PLoS ONE. 12, 3, 13 p., e0173788.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Fusion of Regionally Specified hPSC-Derived Organoids Models Human Brain Development and Interneuron Migration

Xiang, Y., Tanaka, Y., Patterson, B., Kang, Y. J., Govindaiah, G., Roselaar, N., Cakir, B., Kim, K. Y., Lombroso, A. P., Hwang, S. M., Zhong, M., Stanley, E. G., Elefanty, A. G., Naegele, J. R., Lee, S. H., Weissman, S. M. & Park, I-H., 7 Sep 2017, In : Cell Stem Cell. 21, 3, p. 383-398 16 p.

Research output: Contribution to journalArticleResearchpeer-review

130 Citations (Scopus)

Genetic manipulation of the avian urogenital system using in ovo electroporation

Hirst, C. E., Serralbo, O., Ayers, K. L., Roeszler, K. N. & Smith, C. A., 2017, Avian and Reptilian Developmental Biology. Humana Press, Vol. 1650. p. 177-190 14 p. (Methods in Molecular Biology; vol. 1650).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

5 Citations (Scopus)

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

Taylor, R. A., Fraser, M., Livingstone, J., Espiritu, S. M. G., Thorne, H., Huang, V., Lo, W., Shiah, Y-J., Yamaguchi, T. N., Sliwinski, A., Horsburgh, S., Meng, A., Heisler, L. E., Yu, N., Yousif, F., Papargiris, M., Lawrence, M. G., Timms, L., Murphy, D. G., Frydenberg, M. & 8 others, Hopkins, J. F., Bolton, D., Clouston, D., McPherson, J. D., Van Der Kwast, T., Boutros, P. C., Risbridger, G. P. & Bristow, R. G., 9 Jan 2017, In : Nature Communications. 8, 10 p., 13671.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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83 Citations (Scopus)

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes

Chan, A. L., La, H. M., Legrand, J. M. D., Mäkelä, J. A., Eichenlaub, M., De Seram, M., Ramialison, M. & Hobbs, R. M., 12 Sep 2017, In : Stem Cell Reports. 9, 3, p. 956-971 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

Marino, E., Richards, J. L., McLeod, K. H., Stanley, D., Yap, Y. A., Knight, J., McKenzie, C., Kranich, J., Oliveira, A. C., Rossello, F. J., Krishnamurthy, B., Nefzger, C. M., Macia, L., Thorburn, A., Baxter, A. G., Morahan, G., Wong, L. H., Polo, J. M., Moore, R. J., Lockett, T. J. & 4 others, Clarke, J. M., Topping, D. L., Harrison, L. C. & Mackay, C. R., May 2017, In : Nature Immunology. 18, 5, p. 552-562 13 p.

Research output: Contribution to journalArticleResearchpeer-review

198 Citations (Scopus)

Hormonal regulation of platypus Beta-lactoglobulin and monotreme lactation protein genes

Enjapoori, A. K., Lefevre, C. M., Nicholas, K. R. & Sharp, J. A., 1 Feb 2017, In : General and Comparative Endocrinology. 242, p. 38-48 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Human haematopoietic stem cell development: From the embryo to the dish

Ivanovs, A., Rybtsov, S., Ng, E. S., Stanley, E. G., Elefanty, A. G. & Medvinsky, A., 2017, In : Development (Cambridge). 144, 13, p. 2323-2337 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

50 Citations (Scopus)

Human milk bioactivity: lessons from the evolution of lactation

Sharp, J., Watt, A., Lefèvre, C. & Nicholas, K., Apr 2017, In : Australian Biochemist. 48, 1, p. 13-18 6 p.

Research output: Contribution to journalArticleResearch

Open Access
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Hyperglycemia is associated with reduced testicular function and activin dysregulation in the Ins2Akita+/- mouse model of type 1 diabetes

Maresch, C. C., Stute, D. C., Ludlow, H., Hammes, H. P., de Kretser, D. M., Hedger, M. P. & Linn, T., 5 May 2017, In : Molecular and Cellular Endocrinology. 446, p. 91-101 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Imaging, analysing and interpreting branching morphogenesis in the developing kidney

Short, K. M. & Smyth, I. M., 14 Apr 2017, Kidney Development and Disease. Miller, R. K. (ed.). Springer-Verlag London Ltd., p. 233-256 24 p. (Results and Problems in Cell Differentiation; vol. 60).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Impact of endurance exercise training on adipocyte microRNA expression in overweight men

Tsiloulis, T., Pike, J., Powell, D., Rossello, F. J., Canny, B. J., Meex, R. C. R. & Watt, M. J., Jan 2017, In : The FASEB Journal. 31, 1, p. 161-171 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Impact of feeding behaviour on the deformations of the macaque mandible

Panagiotopoulou, O., Iriarte-Díaz, J., Wilshin, S., Dechow, P. C., Taylor, A. B., Mehari Abraha, H. & Ross, C. F., 2017, p. 135-135. 1 p.

Research output: Contribution to conferenceAbstract

Induction of EAO in mice: responses to 2 elevated circulating levels of the activin-binding protein, follistatin

Nicholas, N., Muir, J. A., Hayward, S., Chen, J. L., Stanton, P. G., Gregorevic, P., de Kretser, D. M., Loveland, K. L., Bhushan, S., Meinhardt, A., Fijak, M. & Hedger, M. P., 1 Sep 2017, In : Reproduction. 154, 3, p. 293-305 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Inflammation and Thymus Ageing

Lepletier, A., Alsharif, A. & Chidgey, A. P., 1 Jan 2017, Endocrine Immunology. Savino, W. & Guaraldi, F. (eds.). Karger, Vol. 48. p. 19-36 18 p. (Frontiers of Hormone Research).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

4 Citations (Scopus)

Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells

Bellmaine, S. F., Ovchinnikov, D. A., Manallack, D. T., Cuddy, C. E., Elefanty, A. G., Stanley, E. G., Wolvetang, E. J., Williams, S. J. & Pera, M., 8 Sep 2017, In : eLife. 6, 20 p., e24502.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

Rahmoun, M., Lavery, R., Laurent-Chaballier, S., Bellora, N., Philip, G. K., Rossitto, M., Symon, A., Pailhoux, E., Cammas, F., Chung, J., Bagheri-Fam, S., Murphy, M., Bardwell, V. J., Zarkower, D., Boizet-Bonhoure, B., Clair, P., Harley, V. R. & Poulat, F., 7 Jul 2017, In : Nucleic Acids Research. 45, 12, p. 7191-7211 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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32 Citations (Scopus)

INPP5E regulates phosphoinositide-dependent cilia transition zone function

Dyson, J. M., Conduit, S. E., Feeney, S. J., Hakim, S., DiTommaso, T., Fulcher, A. J., Sriratana, A., Ramm, G., Horan, K. A., Gurung, R., Wicking, C., Smyth, I. & Mitchell, C. A., 2 Jan 2017, In : Journal of Cell Biology. 216, 1, p. 247-263 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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36 Citations (Scopus)

Integrative analysis of copy number and gene expression in breast cancer using formalin-fixed paraffin-embedded core biopsy tissue: A feasibility study

Iddawela, M., Rueda, O. M., Eremin, J., Eremin, O., Cowley, J., Earl, H. M. & Caldas, C., 11 Jul 2017, In : BMC Genomics. 18, 1, 13 p., 526.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Interactome of the inhibitory isoform of the nuclear transporter Importin 13

Fatima, S., Wagstaff, K. M., Lieu, K. G., Davies, R. G., Tanaka, S. S., Yamaguchi, Y. L., Loveland, K. L., Tam, P. P. L. & Jans, D. A., 1 Mar 2017, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 3, p. 546-561 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice

Winship, A. & Dimitriadis, E., Feb 2017, In : Placenta. 50, p. 99-101 3 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice

Winship, A. L., Sorby, K., Correia, J., Rainczuk, A., Yap, J. & Dimitriadis, E., 1 May 2017, In : Placenta. 53, p. 92-100 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Intra- and Intersexual swim bladder dimorphisms in the plainfin midshipman fish (Porichthys notatus): Implications of swim bladder proximity to the inner ear for sound pressure detection

Mohr, R. A., Whitchurch, E. A., Anderson, R. D., Forlano, P. M., Fay, R. R., Ketten, D. R., Cox, T. C. & Sisneros, J. A., 1 Nov 2017, In : Journal of Morphology. 278, 11, p. 1458-1468 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

Menkhorst, E. M., Van Sinderen, M. L., Rainczuk, K., Cuman, C., Winship, A. & Dimitriadis, E., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 8690.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

In vivo bone strain and finite element modeling of a rhesus macaque mandible during mastication

Panagiotopoulou, O., Iriarte-Diaz, J., Wilshin, S., Dechow, P. C., Taylor, A. B., Mehari Abraha, H., Aljunid, S. F. & Ross, C. F., 1 Oct 2017, In : Zoology. 124, p. 13-29 17 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Kallikrein-related peptidase 4 induces cancer-associated fibroblast features in prostate-derived stromal cells

Kryza, T., Silva, L. M., Bock, N., Fuhrman-Luck, R. A., Stephens, C. R., Gao, J., Samaratunga, H., Australian Prostate Cancer BioResource, Lawrence, M. G., Hooper, J. D., Dong, Y., Risbridger, G. P. & Clements, J. A., 1 Oct 2017, In : Molecular Oncology. 11, 10, p. 1307-1329 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse

Dunleavy, J. E. M., Okuda, H., O’Connor, A. E., Merriner, D. J., O’Donnell, L., Jamsai, D., Bergmann, M. & O’Bryan, M. K., 14 Nov 2017, In : PLoS Genetics. 13, 11, 28 p., e1007078.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death

Hirst, C. S., Stamp, L. A., Bergner, A. J., Hao, M. M., Tran, M., Morgan, J., Dutschmann, M., Allen, A. M., Paxinos, G., Furlong, T., McKeown, S. J. & Young, H. M., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16676.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

LIN-32/Atonal Controls Oxygen Sensing Neuron Development in Caenorhabditis elegans

Romanos, T. R., Pladevall-Morera, D., Langebeck-Jensen, K., Hansen, S., Ng, L. & Pocock, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 10 p., 7294.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)
17 Citations (Scopus)

Loss of Cln5 causes altered neurogenesis in a mouse model of a childhood neurodegenerative disorder

Savchenko, E., Singh, Y., Konttinen, H., Lejavova, K., Santos, L. M., Grubman, A., Karkkainen, V., Keksa-Goldsteine, V., Naumenko, N., Tavi, P., White, A. R., Malm, T., Koistinaho, J. & Kanninen, K. M., 1 Sep 2017, In : Disease Models and Mechanisms. 10, 9, p. 1089-1100 12 p.

Research output: Contribution to journalArticleResearchpeer-review

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7 Citations (Scopus)

Loss of thymic innate lymphoid cells leads to impaired thymopoiesis in experimental graft-versus-host disease

Dudakov, J. A., Mertelsmann, A. M., O’Connor, M. H., Jenq, R. R., Velardi, E., Young, L. F., Smith, O. M., Boyd, R. L., van den Brink, M. R. M. & Hanash, A. M., 17 Aug 2017, In : Blood. 130, 7, p. 933-942 10 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

LRGUK1 is part of a multiprotein complex required for manchette function and male fertility

Okuda, H., Deboer, K., O'Connor, A. E., Merriner, D. J., Jamsai, D. & O'Bryan, M. K., 1 Mar 2017, In : The FASEB Journal. 31, 3, p. 1141-1152 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)