Research Output

2018

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Dadaev, T., Saunders, E. J., Newcombe, P. J., Anokian, E., Leongamornlert, D. A., Brook, M. N., Cieza-Borrella, C., Mijuskovic, M., Wakerell, S., Olama, A. A. A., Schumacher, F. R., Berndt, S. I., Benlloch, S., Ahmed, M., Goh, C., Sheng, X., Zhang, Z., Muir, K., Govindasami, K., Lophatananon, A. & 172 others, Stevens, V. L., Gapstur, S. M., Carter, B. D., Tangen, C. M., Goodman, P., Thompson, I. M., Batra, J., Chambers, S., Moya, L., Clements, J., Horvath, L., Tilley, W., Risbridger, G., Gronberg, H., Aly, M., Nordström, T., Pharoah, P., Pashayan, N., Schleutker, J., Tammela, T. L. J., Sipeky, C., Auvinen, A., Albanes, D., Weinstein, S., Wolk, A., Hakansson, N., West, C., Dunning, A. M., Burnet, N., Mucci, L., Giovannucci, E., Andriole, G., Cussenot, O., Cancel-Tassin, G., Koutros, S., Freeman, L. E. B., Sorensen, K. D., Orntoft, T. F., Borre, M., Maehle, L., Grindedal, E. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Martin, R. M., Travis, R. C., Key, T. J., Hamilton, R. J., Fleshner, N. E., Finelli, A., Ingles, S. A., Stern, M. C., Rosenstein, B., Kerns, S., Ostrer, H., Lu, Y. J., Zhang, H. W., Feng, N., Mao, X., Guo, X., Wang, G., Sun, Z., Giles, G. G., Southey, M. C., MacInnis, R. J., Fitzgerald, L. M., Kibel, A. S., Drake, B. F., Vega, A., Gómez-Caamaño, A., Fachal, L., Szulkin, R., Eklund, M., Kogevinas, M., Llorca, J., Castaño-Vinyals, G., Penney, K. L., Stampfer, M., Park, J. Y., Sellers, T. A., Lin, H. Y., Stanford, J. L., Cybulski, C., Wokolorczyk, D., Lubinski, J., Ostrander, E. A., Geybels, M. S., Nordestgaard, B. G., Nielsen, S. F., Weisher, M., Bisbjerg, R., Røder, M. A., Iversen, P., Brenner, H., Cuk, K., Holleczek, B., Maier, C., Luedeke, M., Schnoeller, T., Kim, J., Logothetis, C. J., John, E. M., Teixeira, M. R., Paulo, P., Cardoso, M., Neuhausen, S. L., Steele, L., Ding, Y. C., De Ruyck, K., De Meerleer, G., Ost, P., Razack, A., Lim, J., Teo, S. H., Lin, D. W., Newcomb, L. F., Lessel, D., Gamulin, M., Kulis, T., Kaneva, R., Usmani, N., Slavov, C., Mitev, V., Parliament, M., Singhal, S., Claessens, F., Joniau, S., Van Den Broeck, T., Larkin, S., Townsend, P. A., Aukim-Hastie, C., Gago-Dominguez, M., Castelao, J. E., Martinez, M. E., Roobol, M. J., Jenster, G., Van Schaik, R. H. N., Menegaux, F., Truong, T., Koudou, Y. A., Xu, J., Khaw, K. T., Cannon-Albright, L., Pandha, H., Michael, A., Kierzek, A., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Lindstrom, S., Turman, C., Ma, J., Hunter, D. J., Riboli, E., Siddiq, A., Canzian, F., Kolonel, L. N., Le Marchand, L., Hoover, R. N., Machiela, M. J., Kraft, P., Cook, M., Freedman, M. L., Wiklund, F., Chanock, S. J., Henderson, B. E., Easton, D. F., Haiman, C. A., Eeles, R. A., Conti, D. V., Kote-Jarai, Z. & The PRACTICAL consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 19 p., 2256.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Fine Tuning of Canonical Wnt Stimulation Enhances Differentiation of Pluripotent Stem Cells Independent of β-Catenin-Mediated T-Cell Factor Signaling

Chen, J., Nefzger, C. M., Rossello, F., Sun, Y. B. Y., Lim, S. M., Liu, X., De Boer, S., Knaupp, A. S., Li, J., Davidson, K. C., Polo, J. M. & Barberi, T., 1 Jun 2018, In : Stem Cells. 36, 6, p. 822-833 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Fossil mammals from the Gondolin Dump A ex situ hominin deposits, South Africa

Adams, J. W., 6 Aug 2018, In : PeerJ. 2018, 8, 42 p., e5393.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Functional relationship between dental macrowear and diet in Late Pleistocene and recent modern human populations: Tooth wear inclination in Neanderthals and modern humans

Fiorenza, L., Benazzi, S., Oxilia, G. & Kullmer, O., 1 Mar 2018, In : International Journal of Osteoarchaeology. 28, 2, p. 153-161 9 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Gene editing of stem cells for kidney disease modelling and therapeutic intervention

Lau, R. W. K., Wang, B. & Ricardo, S. D., 1 Nov 2018, In : Nephrology. 23, 11, p. 981-990 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

Generation of RAB39B knockout isogenic human embryonic stem cell lines to model RAB39B-mediated Parkinson's disease

Gao, Y., Wilson, G. R., Bozaoglu, K., Elefanty, A. G., Stanley, E. G., Dottori, M. & Lockhart, P. J., 1 Apr 2018, In : Stem Cell Research. 28, p. 161-164 4 p.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

Dagar, V., Hutchison, W., Muscat, A., Krishnan, A., Hoke, D., Buckle, A., Siswara, P., Amor, D. J., Mann, J., Pinner, J., Colley, A., Wilson, M., Sachdev, R., McGillivray, G., Edwards, M., Kirk, E., Collins, F., Jones, K., Taylor, J., Hayes, I. & 14 others, Thompson, E., Barnett, C., Haan, E., Freckmann, M-L., Turner, A., White, S., Kamien, B., Ma, A., Mackenzie, F., Baynam, G., Kiraly-Borri, C., Field, M., Dudding-Byth, T. & Algar, E., 30 Aug 2018, In : Clinical Epigenetics. 10, 1, 13 p., 114.

Research output: Contribution to journalArticleResearchpeer-review

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3 Citations (Scopus)

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

Zhu, Y., Czauderna, T., Zhao, J., Klapperstueck, M., Mahamad Maifiah, M. H. B., Han, M-L., Lu, J., Sommer, B., Velkov, T., Lithgow, T., Song, J., Schreiber, F. & Li, J., 1 Apr 2018, In : GigaScience. 7, 4, 18 p., giy021.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Geoarchaeological and 3D visualisation approaches for contextualising in-situ fossil bearing palaeokarst in South Africa: A case study from the ∼2.61 Ma Drimolen Makondo

Herries, A. I. R., Murszewski, A., Pickering, R., Mallett, T., Joannes-Boyau, R., Armstrong, B., Adams, J. W., Baker, S., Blackwood, A. F., Penzo-Kajewski, P., Kappen, P., Leece, AB., Martin, J., Rovinsky, D. & Boschian, G., 30 Jul 2018, In : Quaternary International. 483, p. 90-110 21 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

Matejcic, M., Saunders, E. J., Dadaev, T., Brook, M. N., Wang, K., Sheng, X., Al Olama, A. A., Schumacher, F., Ingles, S. A., Govindasami, K., Benlloch, S., Berndt, S., Albanes, D., Koutros, S., Muir, K., Stevens, V. L., Gapstur, S. M., Tangen, C. M., Batra, J., Clements, J. & 7 others, PRACTICAL Consortium, Giles, G., Milne, R. L., Taylor, R., Papargiris, M. M., Risbridger, G. & Southey, M. C., 5 Nov 2018, In : Nature Communications. 9, 11 p., 382.

Research output: Contribution to journalArticleResearchpeer-review

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12 Citations (Scopus)

Get SET: Aligning anatomy demonstrator programmes with Surgical Education and Training selection criteria

Rhodes, D., Fogg, Q. A. & Lazarus, M. D., May 2018, In : ANZ Journal of Surgery. 88, 5, p. E406-E411 6 p.

Research output: Contribution to journalArticleResearchpeer-review

GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance

La, H. M., Chan, A-L., Legrand, J. M. D., Rossello, F. J., Gangemi, C. G., Papa, A., Cheng, Q., Morand, E. F. & Hobbs, R. M., 1 Sep 2018, In : Development (Cambridge). 145, 18, dev165324.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Gonadal and Endocrine Analysis of a Gynandromorphic Chicken

Morris, K. R., Hirst, C. E., Major, A. T., Ezaz, T., Ford, M., Bibby, S., Doran, T. J. & Smith, C. A., 1 Oct 2018, In : Endocrinology. 159, 10, p. 3492-3502 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number

Combes, A. N., Wilson, S., Phipson, B., Binnie, B. B., Ju, A., Lawlor, K. T., Cebrian, C., Walton, S. L., Smyth, I. M., Moritz, K. M., Kopan, R., Oshlack, A. & Little, M. H., Mar 2018, In : Kidney International. 93, 3, p. 589-598 10 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

How does the intrauterine growth restricted heart respond to angiotensin II infusion?

Zohdi, V., Black, M., Pearson, J., Kett, M., Lombardo, P., Schneider, M. & Ravingerova, T., Jul 2018, In : Journal of Molecular and Cellular Cardiology. 120, Supplement, p. 52-53 2 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

Hub connectivity, neuronal diversity, and gene expression in the Caenorhabditis elegans connectome

Arnatkeviciute, A., Fulcher, B. D., Pocock, R. & Fornito, A., 12 Feb 2018, In : PLoS Computational Biology. 14, 2, 32 p., e1005989.

Research output: Contribution to journalArticleResearchpeer-review

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14 Citations (Scopus)

Humanization of the prostate microenvironment reduces homing of PC3 prostate cancer cells to human tissue-engineered bone

McGovern, J. A., Shafiee, A., Wagner, F., Lahr, C. A., Landgraf, M., Meinert, C., Williams, E. D., Russell, P. J., Clements, J. A., Loessner, D., Holzapfel, B. M., Risbridger, G. P. & Hutmacher, D. W., 13 Nov 2018, In : Cancers. 10, 11, 15 p., 438.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage

Loppi, S., Kolosowska, N., Kärkkäinen, O., Korhonen, P., Huuskonen, M., Grubman, A., Dhungana, H., Wojciechowski, S., Pomeshchik, Y., Giordano, M., Kagechika, H., White, A., Auriola, S., Koistinaho, J., Landreth, G., Hanhineva, K., Kanninen, K. & Malm, T., 1 Oct 2018, In : Brain, Behavior, and Immunity. 73, p. 670-681 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Identification of dynamic undifferentiated cell states within the male germline

La, H. M., Mäkelä, J-A., Chan, A-L., Rossello, F. J., Nefzger, C. M., Legrand, J. M. D., De Seram, M., Polo, J. M. & Hobbs, R. M., 19 Jul 2018, In : Nature Communications. 9, 1, 18 p., 2819.

Research output: Contribution to journalArticleResearchpeer-review

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22 Citations (Scopus)

Identification of Pik3ca mutation as a genetic driver of prostate cancer that cooperates with Pten loss to accelerate progression and castration-resistant growth

Pearson, H. B., Li, J., Meniel, V. S., Fennell, C. M., Waring, P., Montgomery, K. G., Rebello, R. J., Macpherson, A. A., Koushyar, S., Furic, L., Cullinane, C., Clarkson, R. W., Smalley, M. J., Simpson, K. J., Phesse, T. J., Shepherd, P. R., Humbert, P. O., Sansom, O. J. & Phillips, W. A., 1 Jun 2018, In : Cancer Discovery. 8, 6, p. 764-779 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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21 Citations (Scopus)

Impact of preterm birth on the developing myocardium of the neonate

Bensley, J. G., Moore, L., De Matteo, R., Harding, R. & Black, M. J., 1 Apr 2018, In : Pediatric Research. 83, 4, p. 880-888 9 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Improving pregnancy outcomes in humans through studies in sheep

Morrison, J. L., Berry, M. J., Botting, K. J., Darby, J. R. T., Frasch, M. G., Gatford, K. L., Giussani, D. A., Gray, C. L., Harding, R., Herrera, E. A., Kemp, M. W., Lock, M. C., McMillen, I. C., Moss, T. J., Musk, G. C., Oliver, M. H., Regnault, T. R. H., Roberts, C. T., Soo, J. Y. & Tellam, R. L., 1 Dec 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 6, p. R1123-R1153 31 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

27 Citations (Scopus)

Induced pluripotent stem cell-derived podocyte-like cells as models for assessing mechanisms underlying heritable disease phenotype: Initial studies using two alport syndrome patient lines indicate impaired potassium channel activity

Haynes, J. M., Selby, J. N., Vandekolk, T. H., Abad, I. P. L., Ho, J. K., Lieuw, W-L., Leach, K., Savige, J., Saini, S., Fisher, C. L. & Ricardo, S. D., 1 Nov 2018, In : Journal of Pharmacology and Experimental Therapeutics. 367, 2, p. 335-347 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy

Marini, K., Croucher, D. R., McCloy, R. A., Vaghjiani, V., Gonzalez-Rajal, A., Hastings, J. F., Chin, V. T., Szczepny, A., Kostyrko, K., Marquez, C., Jayasekara, W. S. N., Alamgeer, M., Boolell, V., Han, J. Z. R., Waugh, T., Lee, H. C., Oakes, S. R., Kumar, B., Harrison, C. A., Hedger, M. P. & 13 others, Lorensuhewa, N., Kita, B., arrow, R. B., Robinson, B. W. S., de Kretser, D. M., Wu, J., Ganju, V., Sweet-Cordero, E. A., Burgess, A., Martelotto, L. G., Rossello, F. J., Cain, J. & Watkins, D. N., 25 Jul 2018, In : Science Translational Medicine. 10, 451, 13 p., eaat3504.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

Voon, H. P. J., Udugama, M., Lin, W., Hii, L., Law, R. H. P., Steer, D. L., Das, P. P., Mann, J. R. & Wong, L. H., 1 Dec 2018, In : Nature Communications. 9, 1, 10 p., 3142.

Research output: Contribution to journalArticleResearchpeer-review

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8 Citations (Scopus)

Interleukin 11 blockade during mid to late gestation does not affect maternal blood pressure, pregnancy viability or subsequent fertility in mice

Winship, A., Menkhorst, E., Van Sinderen, M. & Dimitriadis, E., 1 Mar 2018, In : Reproductive BioMedicine Online. 36, 3, p. 250-258 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice

Winship, A. & Dimitriadis, E., 1 Feb 2018, In : Journal of Reproductive Immunology. 125, p. 32-38 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate-tolerant cells

Porter, L. H., Hashimoto, K., Lawrence, M. G., Pezaro, C., Clouston, D., Wang, H., Papargiris, M., Thorne, H., Li, J., Investigators, K., Ryan, A., Norden, S., Moon, D., Bolton, D. M., Sengupta, S., Frydenberg, M., Murphy, D. G., Risbridger, G. P. & Taylor, R. A., 1 Jun 2018, In : BJU International. 121, 6, p. 971-978 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion

Pleines, I., Lebois, M., Gangatirkar, P., Au, A. E., Lane, R. M., Henley, K. J., Kauppi, M., Corbin, J., Cannon, P., Bernardini, J., Alwis, I., Jarman, K. E., Ellis, S., Metcalf, D., Jackson, S. P., Schoenwaelder, S. M., Kile, B. T. & Josefsson, E. C., 12 Jul 2018, In : Blood. 132, 2, p. 197-209 13 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

KTAO: A kidney tissue atlas ontology to support community-based kidney knowledge base development and data integration

He, Y., Steck, B., Ong, E., Mariani, L., Lienczewski, C., Balis, U., Kretzler, M., Himmelfarb, J., Bertram, J. F., Azeloglu, E., Iyengar, R., Hoshizaki, D. & Mooney, S. D., 22 Dec 2018, Proceedings of the 9th International Conference on Biological Ontology (ICBO 2018). Jaiswal, P., Cooper, L., Haendel, M. A. & Mungall, C. J. (eds.). Aachen, Germany: RWTH Aachen University, Vol. 2285. 6 p. (CEUR Workshop Proceedings).

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

Open Access
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Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

Goldie, S. J., Cottle, D. L., Tan, F. H., Roslan, S., Srivastava, S., Brady, R., Partridge, D. D., Auden, A., Smyth, I. M., Jane, S. M., Dworkin, S. & Darido, C., 19 Oct 2018, In : Cell Death & Disease. 9, 11, 12 p., 1072.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility

Nguyen, Q. N., Zerafa, N., Liew, S. H., Morgan, F. H., Strasser, A., Scott, C. L., Findlay, J. K., Hickey, M. & Hutt, K. J., 1 Jun 2018, In : Cell Death & Disease. 9, 6, 12 p., 633.

Research output: Contribution to journalArticleResearchpeer-review

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27 Citations (Scopus)

Maladaptive structural remodelling of the heart following preterm birth

Le, B., Sutherland, M. R. & Black, M. J., 1 Feb 2018, In : Current Opinion in Physiology. 1, p. 89-94 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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2 Citations (Scopus)

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017

Gillessen, S., Attard, G., Beer, T. M., Beltran, H., Bossi, A., Bristow, R., Carver, B. S., Castellano, D., Chung, B. H., Clarke, N., Daugaard, G., Davis, I. D., De Bono, J. S., dos Reis, R. B., Drake, C. G., Eeles, R., Efstathiou, E., Evans, C. P., Fanti, S., Feng, F. & 1 others, Frydenberg, M., Feb 2018, In : European Urology. 73, 2, p. 178-211 34 p.

Research output: Contribution to journalArticleResearchpeer-review

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237 Citations (Scopus)

Maternal low-protein diet programmes low ovarian reserve in offspring

Winship, A. L., Gazzard, S. E., Cullen-McEwen, L. A., Bertram, J. F. & Hutt, K., 10 Jul 2018, In : Reproduction. 156, 4, p. 299-311 13 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy

Daly, C. D., Ghosh, P., Zannettino, A. C. W., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Jain, K., Sher, I., Vais, A., Cohen, C., Chandra, R. V. & Goldschlager, T., 1 Mar 2018, In : The Spine Journal. 18, 3, p. 491-506 16 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Method of derivation and differentiation of mouse embryonic stem cells generating synchronous neuronal networks

Gazina, E. V., Morrisroe, E., Mendis, G. D. C., Michalska, A. E., Chen, J., Nefzger, C. M., Rollo, B. N., Reid, C. A., Pera, M. F. & Petrou, S., 1 Jan 2018, In : Journal of Neuroscience Methods. 293, p. 53-58 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma

Kondrashova, O., Topp, M., Nesic, K., Lieschke, E., Ho, G. Y., Harrell, M. I., Zapparoli, G. V., Hadley, A., Holian, R., Boehm, E., Heong, V., Sanij, E., Pearson, R. B., Krais, J. J., Johnson, N., McNally, O., Ananda, S., Alsop, K., Hutt, K. J., Kaufmann, S. H. & 11 others, Lin, K. K., Harding, T. C., Traficante, N., Australian Ovarian Cancer Study (AOCS), deFazio, A., McNeish, I. A., Bowtell, D. D., Swisher, E. M., Dobrovic, A., Wakefield, M. J. & Scott, C. L., 1 Dec 2018, In : Nature Communications. 9, 1, 16 p., 3970.

Research output: Contribution to journalArticleResearchpeer-review

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45 Citations (Scopus)

miR-222 isoforms are differentially regulated by type-I interferon

Nejad, C., Pillman, K. A., Siddle, K. J., Pépin, G., Anko, M. L., McCoy, C. E., Beilharz, T. H., Quintana-Murci, L., Goodall, G. J., Bracken, C. P. & Gantier, M. P., 1 Mar 2018, In : RNA. 24, 3, p. 332-341 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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13 Citations (Scopus)

Modelling intestinal carcinogenesis using in vitro organoid cultures

Jardé, T., Kerr, G., Akhtar, R. & Abud, H. E., 2018, Methods in Molecular Biology. Humana Press, Vol. 1725. p. 41-52 12 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)

Moderate preterm birth affects right ventricular structure and function and pulmonary artery blood flow in adult sheep

Mrocki, M. M., Nguyen, V. B., Lombardo, P., Sutherland, M. R., Bensley, J. G., Nitsos, I., Allison, B. J., Harding, R., De Matteo, R., Schneider, M., Polglase, G. R. & Black, M. J., 1 Dec 2018, In : Journal of Physiology. 596, 23, p. 5965-5975 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Morphology and function of the lamb ileum following preterm birth

Flores, T. J., Nguyen, V. B., Widdop, R. E., Sutherland, M. R., Polglase, G. R., Abud, H. E. & Black, M. J., 29 Jan 2018, In : Frontiers in Pediatrics. 6, 11 p., 8.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Mouse double minute homologue 2 (MDM2) downregulation by miR-661 impairs human endometrial epithelial cell adhesive capacity

Winship, A., Ton, A., Van Sinderen, M., Menkhorst, E., Rainczuk, K., Griffiths, M., Cuman, C. & Dimitriadis, E., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 3, p. 477-486 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

Navone, N. M., van Weerden, W. M., Vessella, R. L., Williams, E. D., Wang, Y., Isaacs, J. T., Nguyen, H. M., Culig, Z., van der Pluijm, G., Rentsch, C. A., Marques, R. B., de Ridder, C. M. A., Bubendorf, L., Thalmann, G. N., Brennen, W. N., Santer, F. R., Moser, P. L., Shepherd, P., Efstathiou, E., Xue, H. & 9 others, Lin, D., Collins, A., Maitland, N., Buzza, M., Kouspou, M., Achtman, A., Taylor, R. A., Risbridger, G. & Corey, E., 1 Dec 2018, In : Prostate. 78, 16, p. 1262-1282 21 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Multidose 5-Fluorouracil is Highly Toxic to Growing Ovarian Follicles in Mice

Stringer, J. M., Swindells, E. O. K., Zerafa, N., Liew, S. H. & Hutt, K. J., 1 Nov 2018, In : Toxicological sciences : an official journal of the Society of Toxicology. 166, 1, p. 97-107 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Mutant NR5A1/SF-1 in patients with disorders of sex development shows defective activation of the SOX9 TESCO enhancer

Sreenivasan, R., Ludbrook, L. M., Fisher, B. D., Declosmenil, F., Knower, K. C., Croft, B. M., Bird, A. D., Ryan, J., Bashamboo, A., Sinclair, A., Koopman, P., McElreavey, K., Poulat, F. & Harley, V. R., 1 Dec 2018, In : Human Mutation. 39, 12, p. 1861-1874 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

NKX2-5 regulates human cardiomyogenesis via a HEY2 dependent transcriptional network

Anderson, D. J., Kaplan, D. I., Bell, K. M., Koutsis, K., Haynes, J. M., Mills, R. J., Phelan, D. G., Qian, E. L., Leitoguinho, A. R., Arasaratnam, D., Labonne, T., Ng, E. S., Davis, R. P., Casini, S., Passier, R., Hudson, J. E., Porrello, E. R., Costa, M. W., Rafii, A., Curl, C. L. & 9 others, Delbridge, L. M., Harvey, R. P., Oshlack, A., Cheung, M. M., Mummery, C. L., Petrou, S., Elefanty, A. G., Stanley, E. G. & Elliott, D. A., 10 Apr 2018, In : Nature Communications. 9, 1, 13 p., 1373.

Research output: Contribution to journalArticleResearchpeer-review

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20 Citations (Scopus)

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

Tye, H., Yu, C. H., Simms, L. A., de Zoete, M. R., Kim, M. L., Zakrzewski, M., Penington, J. S., Harapas, C. R., Souza-Fonseca-Guimaraes, F., Wockner, L. F., Preaudet, A., Mielke, L. A., Wilcox, S. A., Ogura, Y., Corr, S. C., Kanojia, K., Kouremenos, K. A., De Souza, D. P., McConville, M. J., Flavell, R. A. & 6 others, Gerlic, M., Kile, B. T., Papenfuss, A. T., Putoczki, T. L., Radford-Smith, G. L. & Masters, S. L., 13 Sep 2018, In : Nature Communications. 9, 1, 11 p., 3728.

Research output: Contribution to journalArticleResearchpeer-review

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20 Citations (Scopus)

Novel imaging of the prostate reveals spontaneous gland contraction and excretory duct quiescence together with different drug effects

Kügler, R., Mietens, A., Seidensticker, M., Tasch, S., Wagenlehner, F. M., Kaschtanow, A., Tjahjono, Y., Tomczyk, C. U., Beyer, D., Risbridger, G. P., Exintaris, B., Ellem, S. J. & Middendorff, R., 1 Mar 2018, In : The FASEB Journal. 32, 3, p. 1130-1138 9 p.

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Oocyte meiotic resumption upon puberty

Adhikari, D. & Carroll, J., 2018, Encyclopedia of Reproduction: Gametogenesis, Fertilization and Early Development. Skinner, M. K., McCarrey, J. R. & Yan, W. (eds.). 2nd ed. Oxford, UK: Elsevier, Vol. 3. p. 167-171 5 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review