Research Output

2020

Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo

Estermann, M. A., Williams, S., Hirst, C. E., Roly, Z. Y., Serralbo, O., Adhikari, D., Powell, D., Major, A. T. & Smith, C. A., 7 Apr 2020, In : Cell Reports. 31, 1, 19 p., 107491.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Introduction to a special issue on kidney development and disease

Sutherland, M. R., 2 Jul 2020, (Accepted/In press) In : Anatomical Record. 4 p.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

Knowing what's growing: Why ductal and intraductal prostate cancer matter

Lawrence, M. G., Porter, L. H., Clouston, D., Murphy, D. G., Frydenberg, M., Taylor, R. A. & Risbridger, G. P., 4 Mar 2020, In : Science Translational Medicine. 12, 533, 15 p., aaz0152.

Research output: Contribution to journalReview ArticleResearchpeer-review

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019

Gillessen, S., Attard, G., Beer, T. M., Beltran, H., Bjartell, A., Bossi, A., Briganti, A., Bristow, R. G., Chi, K. N., Clarke, N., Davis, I. D., de Bono, J., Drake, C. G., Duran, I., Eeles, R., Efstathiou, E., Evans, C. P., Fanti, S., Feng, F. Y., Fizazi, K. & 52 others, Frydenberg, M., Gleave, M., Halabi, S., Heidenreich, A., Heinrich, D., Higano, C. T. S., Hofman, M. S., Hussain, M., James, N., Kanesvaran, R., Kantoff, P., Khauli, R. B., Leibowitz, R., Logothetis, C., Maluf, F., Millman, R., Morgans, A. K., Morris, M. J., Mottet, N., Mrabti, H., Murphy, D. G., Murthy, V., Oh, W. K., Ost, P., O'Sullivan, J. M., Padhani, A. R., Parker, C., Poon, D. M. C., Pritchard, C. C., Reiter, R. E., Roach, M., Rubin, M., Ryan, C. J., Saad, F., Sade, J. P., Sartor, O., Scher, H. I., Shore, N., Small, E., Smith, M., Soule, H., Sternberg, C. N., Steuber, T., Suzuki, H., Sweeney, C., Sydes, M. R., Taplin, M. E., Tombal, B., Türkeri, L., van Oort, I., Zapatero, A. & Omlin, A., Apr 2020, In : European Urology. 77, 4, p. 508-547 40 p.

Research output: Contribution to journalArticleOtherpeer-review

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24 Citations (Scopus)

Maternal hypoxia developmentally programs low podocyte endowment in male, but not female offspring

Gonçalves, G. D., Walton, S. L., Gazzard, S. E., van der Wolde, J., Mathias, P. C. F., Moritz, K. M., Cullen-McEwen, L. A. & Bertram, J. F., 27 Jan 2020, (Accepted/In press) In : Anatomical Record. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Melanoblasts Populate the Mouse Choroid Earlier in Development Than Previously Described

McMenamin, P. G., Shields, G. T., Seyed-Razavi, Y., Kalirai, H., Insall, R. H., Machesky, L. M. & Coupland, S. E., Aug 2020, In : Investigative Ophthalmology and Visual Science. 61, 10, 9 p., 33.

Research output: Contribution to journalArticleResearchpeer-review

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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

Jardé, T., Chan, W. H., Rossello, F. J., Kaur Kahlon, T., Theocharous, M., Kurian Arackal, T., Flores, T., Giraud, M., Richards, E., Chan, E., Kerr, G., Engel, R. M., Prasko, M., Donoghue, J. F., Abe, S., Phesse, T. J., Nefzger, C. M., McMurrick, P. J., Powell, D. R., Daly, R. J. & 2 others, Polo, J. M. & Abud, H. E., 2020, (Accepted/In press) In : Cell Stem Cell. 17 p.

Research output: Contribution to journalArticleResearchpeer-review

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Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

Deo, P., Chow, S. H., Han, M-L., Speir, M., Huang, C., Schittenhelm, R. B., Dhital, S., Emery, J., Li, J., Kile, B. T., Vince, J. E., Lawlor, K. E. & Naderer, T., 17 Aug 2020, (Accepted/In press) In : Nature Microbiology. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Moderate episodic prenatal alcohol does not impact female offspring fertility in rats

McReight, E. K., Liew, S. H., Steane, S. E., Hutt, K. J., Moritz, K. M. & Akison, L. K., May 2020, In : Reproduction. 159, 5, p. 615-626 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Moderate prenatal ethanol exposure in the rat promotes kidney cell apoptosis, nephron deficits, and sex-specific kidney dysfunction in adult offspring

Akison, L. K., Probyn, M. E., Gray, S. P., Cullen-McEwen, L. A., Tep, K., Steane, S. E., Gobe, G. C., Wlodek, M. E., Bertram, J. F. & Moritz, K. M., 27 Jan 2020, (Accepted/In press) In : Anatomical Record. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Molecular signature of interleukin-22 in colon carcinoma cells and organoid models

Rudloff, I., Jardé, T., Bachmann, M., Elgass, K. D., Kerr, G., Engel, R., Richards, E., Oliva, K., Wilkins, S., McMurrick, P. J., Abud, H. E., Mühl, H. & Nold, M. F., Feb 2020, In : Translational Research. 216, p. 1-22 22 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Morphometric analysis of the hominin talus: Evolutionary and functional implications

Sorrentino, R., Carlson, K. J., Bortolini, E., Minghetti, C., Feletti, F., Fiorenza, L., Frost, S., Jashashvili, T., Parr, W., Shaw, C., Su, A., Turley, K., Wroe, S., Ryan, T. M., Belcastro, M. G. & Benazzi, S., May 2020, In : Journal of Human Evolution. 142, 21 p., 102747.

Research output: Contribution to journalArticleResearchpeer-review

Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids

Motazedian, A., Bruveris, F. F., Kumar, S. V., Schiesser, J. V., Chen, T., Ng, E. S., Chidgey, A. P., Wells, C. A., Elefanty, A. G. & Stanley, E. G., 6 Jan 2020, In : Nature Cell Biology. 22, 1, p. 60-73 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

NMN does not protect the ovarian reserve from cancer treatments

Stringer, J., Groenewegen, E., Liew, S. H. & Hutt, K., Feb 2020, In : Reproduction. 159, 2, p. 105-113 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Omics technologies for kidney disease research

Wang, D., Yang, J., Fan, J., Chen, W., Nikolic-Paterson, D. J. & Li, J., 26 Jun 2020, (Accepted/In press) In : Anatomical Record. 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

1 Citation (Scopus)

Oocytes can efficiently repair DNA double-strand breaks to restore genetic integrity and protect offspring health

Stringer, J. M., Winship, A., Zerafa, N., Wakefield, M. & Hutt, K., 26 May 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 21, p. 11513–11522 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Parameter estimation for a point-source diffusion-decay morphogen model

Flegg, M. B., Muñoz, M. A., Smith-Miles, K., Yuen, W. S., Flegg, J. A. & Carroll, J., Jun 2020, In : Journal of Mathematical Biology. 80, p. 2227–2255 29 p.

Research output: Contribution to journalArticleResearchpeer-review

Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice

Dall, G. V., Vieusseux, J., Seyed-Razavi, Y., Godde, N., Ludford-Menting, M., Russell, S. M., Ashworth, A., Anderson, R. L., Risbridger, G. P., Shackleton, M. & Britt, K. L., 21 Jul 2020, (Accepted/In press) In : Breast Cancer Research and Treatment. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Patient-Derived Colorectal Cancer Organoids Upregulate Revival Stem Cell Marker Genes following Chemotherapeutic Treatment

Engel, R. M., Chan, W. H., Nickless, D., Hlavca, S., Richards, E., Kerr, G., Oliva, K., McMurrick, P. J., Jarde, T. & Abud, H. E., 2 Jan 2020, In : Journal of Clinical Medicine. 9, 1, 13 p., 128.

Research output: Contribution to journalArticleResearchpeer-review

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Percutaneous intrarenal transplantation of differentiated induced pluripotent stem cells into newborn mice

Lau, R. W. K., Al-Rubaie, A., Saini, S., Wise, A. F. & Ricardo, S. D., 11 Feb 2020, (Accepted/In press) In : Anatomical Record. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Personalized medicine—Current and emerging predictive and prognostic biomarkers in colorectal cancer

Koulis, C., Yap, R., Engel, R., Jardé, T., Wilkins, S., Solon, G., Shapiro, J. D., Abud, H. & McMurrick, P., Apr 2020, In : Cancers. 12, 4, 27 p., 812.

Research output: Contribution to journalReview ArticleResearchpeer-review

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1 Citation (Scopus)

Predictive factors of complete pathological response in patients with locally advanced rectal cancer

Engel, R. M., Oliva, K., Koulis, C., Yap, R. & McMurrick, P. J., 30 May 2020, In : International Journal of Colorectal Disease. 35, p. 1759-1767 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Profilin-1 is dysregulated in endometroid (type I) endometrial cancer promoting cell proliferation and inhibiting pro-inflammatory cytokine production

George, L., Winship, A., Sorby, K., Dimitriadis, E. & Menkhorst, E., 14 Aug 2020, (Accepted/In press) In : Biochemical and Biophysical Research Communications. 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Repeated dose (90 days) oral toxicity study of ursolic acid in Han-Wistar rats

Geerlofs, L., He, Z., Xiao, S. & Xiao, Z-C., 2020, In : Toxicology reports. 7, p. 610-623 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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1 Citation (Scopus)

Reproductive health research in Australia and New Zealand: Highlights from the Annual Meeting of the Society for Reproductive Biology, 2019

Winship, A., Donoghue, J., Houston, B. J., Martin, J. H., Lord, T., Adwal, A., Gonzalez, M., Desroziers, E., Ahmad, G., Richani, D. & Bromfield, E. G., 2020, In : Reproduction, Fertility and Development. 32, 7, p. 637-647 11 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

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Smad4 promotes diabetic nephropathy by modulating glycolysis and OXPHOS

Li, J., Sun, Y. B. Y., Chen, W., Fan, J., Li, S., Qu, X., Chen, Q., Chen, R., Zhu, D., Zhang, J., Wu, Z., Chi, H., Crawford, S., Oorschot, V., Puelles, V. G., Kerr, P. G., Ren, Y., Nilsson, S. K., Christian, M., Tang, H. & 4 others, Chen, W., Bertram, J. F., Nikolic-Paterson, D. J. & Yu, X., 5 Feb 2020, In : EMBO Reports. 21, 2, 20 p., e48781.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

SOX3 promotes generation of committed spermatogonia in postnatal mouse testes

McAninch, D., Mäkelä, J-A., La, H. M., Hughes, J. N., Lovell-Badge, R., Hobbs, R. M. & Thomas, P. Q., 21 Apr 2020, In : Scientific Reports. 10, 1, 13 p., 6751.

Research output: Contribution to journalArticleResearchpeer-review

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1 Citation (Scopus)

STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression

Balic, J. J., Albargy, H., Luu, K., Kirby, F. J., Jayasekara, W. S. N., Mansell, F., Garama, D. J., De Nardo, D., Baschuk, N., Louis, C., Humphries, F., Fitzgerald, K., Latz, E., Gough, D. J. & Mansell, A., 30 Jul 2020, In : Nature Communications. 11, 1, 11 p., 3816.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Syndecans in Inflammation at a Glance

Gopal, S., 18 Feb 2020, In : Frontiers in Immunology. 11, 8 p., 227.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

Balka, K. R., Louis, C., Saunders, T. L., Smith, A. M., Calleja, D. J., D'Silva, D. B., Moghaddas, F., Tailler, M., Lawlor, K. E., Zhan, Y., Burns, C. J., Wicks, I. P., Miner, J. J., Kile, B. T., Masters, S. L. & De Nardo, D., 7 Apr 2020, In : Cell Reports. 31, 1, 22 p., 107492.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

The application of human pluripotent stem cells to model the neuronal and glial components of neurodevelopmental disorders

Lee, K. M., Hawi, Z. H., Parkington, H. C., Parish, C. L., Kumar, P. V., Polo, J. M., Bellgrove, M. A. & Tong, J., Feb 2020, In : Molecular Psychiatry. 25, p. 368-378 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

The EMT Modulator SNAI1 Contributes to AML Pathogenesis via Its Interaction With LSD1

Carmichael, C., Wang, J., Nguyen, T., Kolawole, O., Benyoucef, A., De Mazière, C., Milne, A., Samuel, S., Gillinder, K., Hediyeh-Zadeh, S., Vo, A. N. Q., Huang, Y., Knezevic, K., McInnes, W. R. L., Shields, B. J., Mitchell, H., Ritchie, M. E., Lammens, T., Lintermans, B., Van Vlierberghe, P. & 17 others, Wong, N., Haigh, K., Thoms, J. A. I., Toulmin, E., Curtis, D., Oxley, E., Dickins, R., Beck, D., Perkins, A., McCormack, M. P., Davis, M. J., Berx, G., Zuber, J., Pimanda, J. E., Kile, B. T., Goossens, S. & Haigh, J. J., 5 May 2020, (Accepted/In press) In : Blood. 40 p.

Research output: Contribution to journalArticleResearchpeer-review

The functional role of the Carabelli trait in early and late hominins

Fiorenza, L., Menter, C. G., Fung, S., Lee, J., Kaidonis, J., Moggi-Cecchi, J., Townsend, G. & Kullmer, O., Aug 2020, In : Journal of Human Evolution. 145, 14 p., 102816.

Research output: Contribution to journalArticleResearchpeer-review

The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis

Zhang, X., Yang, L., Szeto, P., Abali, G. K., Zhang, Y., Kulkarni, A., Amarasinghe, K., Li, J., Vergara, I. A., Molania, R., Papenfuss, A. T., McLean, C., Shackleton, M. & Harvey, K. F., 19 Jun 2020, (Accepted/In press) In : Oncogene. 15 p.

Research output: Contribution to journalArticleResearchpeer-review

The influence of mobility strategy on the modern human talus

Sorrentino, R., Stephens, N. B., Carlson, K. J., Figus, C., Fiorenza, L., Frost, S., Harcourt-Smith, W., Parr, W., Saers, J., Turley, K., Wroe, S., Belcastro, M. G., Ryan, T. M. & Benazzi, S., Mar 2020, In : American Journal of Physical Anthropology. 171, 3, p. 456-469 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The PARP inhibitor, olaparib, depletes the ovarian reserve in mice: implications for fertility preservation

Winship, A. L., Griffiths, M., Lliberos Requesens, C., Sarma, U., Phillips, K-A. & Hutt, K. J., 30 Jun 2020, (Accepted/In press) In : Human Reproduction. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The regulation of Yorkie, YAP and TAZ: new insights into the Hippo pathway

Manning, S. A., Kroeger, B. & Harvey, K. F., 27 Apr 2020, In : Development (Cambridge). 147, 8, 10 p., 179069.

Research output: Contribution to journalReview ArticleResearchpeer-review

2 Citations (Scopus)

The Spectrum of Learning and Teaching: The Impact of a Fourth-Year Anatomy Course on Medical Student Knowledge and Confidence

Lufler, R. S., Lazarus, M. D. & Stefanik, J. J., Jan 2020, In : Anatomical Sciences Education. 13, 1, p. 19-29 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Ultra-high field diffusion tensor imaging identifies discrete patterns of concussive injury in the rodent brain

To, X. V., Benetatos, J., Soni, N., Liu, D., Mehari Abraha, H., Yan, W., Panagiotopoulou, O. & Nasrallah, F., 8 Jul 2020, (Accepted/In press) In : Journal of Neurotrauma. 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells

Chew, S., Lampinen, R., Saveleva, L., Korhonen, P., Mikhailov, N., Grubman, A., Polo, J. M., Wilson, T., Komppula, M., Rönkkö, T., Gu, C., Mackay-Sim, A., Malm, T., White, A. R., Jalava, P. & Kanninen, K. M., 1 Jun 2020, In : Particle and Fibre Toxicology. 17, 1, 15 p., 18.

Research output: Contribution to journalArticleResearchpeer-review

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WNT signalling in the normal human adult testis and in male germ cell neoplasms

Young, J. C., Kerr, G., Micati, D., Nielsen, J. E., Rajpert-De Meyts, E., Abud, H. E. & Loveland, K. L., 15 Jul 2020, (Accepted/In press) In : Human Reproduction. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Your blood pressure might be normal, but what about your podocytes?

Bertram, J. F., Sep 2020, In : Kidney International. 98, 3, p. 545-547 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

‘Snail factors in testicular germ cell tumours and their regulation by the BMP4 signalling pathway’

Micati, D. J., Radhakrishnan, K., Young, J. C., Rajpert-De Meyts, E., Hime, G. R., Abud, H. E. & Loveland, K. L., 22 May 2020, (Accepted/In press) In : Andrology. 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2019

A balancing act: PHLPP2 fine tunes AKT activity and MYC stability in prostate cancer

Toivanen, R. & Furic, L., 3 Jun 2019, In : Journal of Cell Biology. 218, 6, p. 1771-1772 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Acknowledgements: the Levin/Kile rule

Levin, J. & Kile, B. T., 1 Jan 2019, In : Platelets. 30, 2, 1 p.

Research output: Contribution to journalLetterOtherpeer-review

A critical role for estrogen signaling in penis development

Govers, L. C., Phillips, T. R., Mattiske, D. M., Rashoo, N., Black, J. R., Sinclair, A., Baskin, L. S., Risbridger, G. P. & Pask, A. J., Sep 2019, In : The FASEB Journal. 33, 9, p. 10383-10392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Activin A target genes are differentially expressed between normal and neoplastic adult human testes: clues to gonocyte fate choice

Szarek, M., Bergmann, M., Konrad, L., Schuppe, H. C., Kliesch, S., Hedger, M. P. & Loveland, K. A. L., 1 Jan 2019, In : Andrology. 7, 1, p. 31-41 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Saad, M. I., Alhayyani, S., McLeod, L., Yu, L., Alanazi, M., Deswaerte, V., Tang, K., Jarde, T., Smith, J. A., Prodanovic, Z., Tate, M. D., Balic, J. J., Watkins, D. N., Cain, J. E., Bozinovski, S., Algar, E., Kohmoto, T., Ebi, H., Ferlin, W., Garbers, C. & 4 others, Ruwanpura, S., Sagi, I., Rose-John, S. & Jenkins, B. J., Apr 2019, In : EMBO Molecular Medicine. 11, 4, 19 p., e9976.

Research output: Contribution to journalArticleResearchpeer-review

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12 Citations (Scopus)

Adding insult to injury: improving regenerative capacity of the aged thymus following clinically induced damage

Dudakov, J., Hun, M. L., Wong, K., Hollander, G. & Chidgey, A. P., 2 Apr 2019, Thymus Transcriptome and Cell Biology. Passos, G. (ed.). Switzerland: Springer, p. 273-294 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Adding Marrow Adiposity and Cortical Porosity to Femoral Neck Areal Bone Mineral Density Improves the Discrimination of Women With Nonvertebral Fractures From Controls

Zebaze, R., Osima, M., Bui, M., Lukic, M., Wang, X., Ghasem-Zadeh, A., Eriksen, E. F., Vais, A., Shore-Lorenti, C., Ebeling, P. R., Seeman, E. & Bjørnerem, Å., Aug 2019, In : Journal of Bone and Mineral Research. 34, 8, p. 1451-1460 10 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)