Research Output

2020

15-Day subchronic developmental toxicity studies of ursolic acid in rats

Geerlofs, L., He, Z., Xiao, S. & Xiao, Z-C., Oct 2020, In : Food and Chemical Toxicology. 144, 17 p., 111537.

Research output: Contribution to journalArticleResearchpeer-review

3D approaches to model the tumor microenvironment of pancreatic cancer

Tomás-Bort, E., Kieler, M., Sharma, S., Candido, J. B. & Loessner, D., 2020, In : Theranostics. 10, 11, p. 5074-5089 16 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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2 Citations (Scopus)

ABCA12 regulates insulin secretion from β-cells

Ursino, G. M., Fu, Y., Cottle, D. L., Mukhamedova, N., Jones, L. K., Low, H., Tham, M. S., Gan, W. J., Mellett, N. A., Das, P. P., Weir, J. M., Ditiatkovski, M., Fynch, S., Thorn, P., Thomas, H. E., Meikle, P. J., Parkington, H. C., Smyth, I. M. & Sviridov, D., 4 Mar 2020, In : EMBO Reports. 21, 3, 19 p., e48692.

Research output: Contribution to journalArticleResearchpeer-review

Absence of TRIM32 Leads to Reduced GABAergic Interneuron Generation and Autism-like Behaviors in Mice via Suppressing mTOR Signaling

Zhu, J. W., Zou, M. M., Li, Y. F., Chen, W. J., Liu, J. C., Chen, H., Fang, L. P., Zhang, Y., Wang, Z. T., Chen, J. B., Huang, W., Li, S., Jia, W. Q., Wang, Q. Q., Zhen, X. C., Liu, C. F., Li, S., Xiao, Z. C., Xu, G. Q., Schwamborn, J. C. & 3 others, Schachner, M., Ma, Q. H. & Xu, R. X., 14 May 2020, In : Cerebral Cortex. 30, 5, p. 3240-3258 19 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Activin A determines steroid levels and composition in the fetal testis

Whiley, P. A. F., O'Donnell, L., Moody, S. C., Handelsman, D. J., Young, J. C., Richards, E. A., Almstrup, K., Western, P. S. & Loveland, K. L., 10 Apr 2020, (Accepted/In press) In : Endocrinology. 41 p.

Research output: Contribution to journalArticleResearchpeer-review

A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture

Grubman, A., Vandekolk, T. H., Schröder, J., Sun, G., Hatwell-Humble, J., Chan, J., Oksanen, M., Lehtonen, S., Hunt, C., Koistinaho, J. E., Nilsson, S. K., Haynes, J. M., Pouton, C. W. & Polo, J. M., 9 Jun 2020, In : Stem Cell Reports. 14, 6, p. 1018-1032 15 p.

Research output: Contribution to journalArticleResearchpeer-review

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Adhesion G-protein-coupled receptor, GPR56, is required for Müllerian duct development in the chick

Roly, Z. Y., Major, A. T., Fulcher, A., Estermann, M. A., Hirst, C. E. & Smith, C. A., Feb 2020, In : Journal of Endocrinology. 244, 2, p. 395-413 19 p.

Research output: Contribution to journalArticleResearchpeer-review

AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease

Conduit, S. E., Davies, E. M., Ooms, L. M., Gurung, R., Mcgrath, M. J., Hakim, S., Cottle, D. L., Smyth, I. M., Dyson, J. M. & Mitchell, C. A., 1 Jan 2020, In : Human Molecular Genetics. 29, 1, p. 31-48 18 p.

Research output: Contribution to journalArticleResearchpeer-review

A Look at the Anatomy Educator Job Market: Anatomists Remain in Short Supply

Wilson, A. B., Notebaert, A. J., Schaefer, A. F., Moxham, B. J., Stephens, S., Mueller, C., Lazarus, M. D., Katrikh, A. Z. & Brooks, W. S., 1 Jan 2020, In : Anatomical Sciences Education. 13, 1, p. 91-101 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Alterations in the methylome of the stromal tumour microenvironment signal the presence and severity of prostate cancer

Lawrence, M. G., Pidsley, R., Niranjan, B., Papargiris, M., Pereira, B. A., Richards, M., Teng, L., Norden, S., Ryan, A., Frydenberg, M., Stirzaker, C., Taylor, R. A., Risbridger, G. P. & Clark, S. J., 18 Mar 2020, In : Clinical Epigenetics. 12, 1, 18 p., 48.

Research output: Contribution to journalArticleResearchpeer-review

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Altered Brain Endothelial Cell Phenotype from a Familial Alzheimer Mutation and Its Potential Implications for Amyloid Clearance and Drug Delivery

Oikari, L. E., Pandit, R., Stewart, R., Cuní-López, C., Quek, H., Sutharsan, R., Rantanen, L. M., Oksanen, M., Lehtonen, S., de Boer, C. M., Polo, J. M., Götz, J., Koistinaho, J. & White, A. R., 12 May 2020, In : Stem Cell Reports. 14, 5, p. 924-939 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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A mouse model of Staphylococcus aureus small intestinal infection

Larcombe, S., Jiang, J-H., Hutton, M. L., Abud, H. E., Peleg, A. Y. & Lyras, D., 31 Jan 2020, In : Journal of Medical Microbiology. 69, 2, p. 290-297 8 p.

Research output: Contribution to journalArticleResearchpeer-review

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Analysis of structure and gene expression in developing kidneys of male and female rats exposed to low protein diets in utero

Wood-Bradley, R. J., Henry, S. L., Barrand, S., Giot, A., Eipper, L., Bertram, J. F., Cullen-McEwen, L. A. & Armitage, J. A., 21 Jun 2020, (Accepted/In press) In : Anatomical Record. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

A practical guide to the stereological assessment of glomerular number, size, and cellular composition

Sutherland, M. R., Vojisavljevic, D. & Black, M. J., 21 Jan 2020, (Accepted/In press) In : Anatomical Record. 14 p.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

A single amino acid change in the EGL-46 transcription factor causes defects in BAG neuron specification

Godini, R., Langebeck-Jensen, K. & Pocock, R., 25 Feb 2020, In : microPublication Biology. 3 p.

Research output: Contribution to journalArticleResearchpeer-review

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Biological Considerations in Scaling Up Therapeutic Cell Manufacturing

Cherian, D. S., Bhuvan, T., Meagher, L. & Heng, T. S. P., 13 May 2020, In : Frontiers in Pharmacology. 11, 25 p., 654.

Research output: Contribution to journalReview ArticleResearchpeer-review

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Biomechanical insights into the role of foot pads during locomotion in camelid species

Clemente, C. J., Dick, T. J. M., Glen, C. L. & Panagiotopoulou, O., 2 Mar 2020, In : Scientific Reports. 10, 1, 12 p., 3856.

Research output: Contribution to journalArticleResearchpeer-review

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Caenorhabditis elegans body wall muscles sense mechanical signals with an amiloride-sensitive cation channel

Yan, Z., Su, Z., Cheng, X. & Liu, J., 25 Jun 2020, In : Biochemical and Biophysical Research Communications. 527, 2, p. 581-587 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Calcium in Cell-Extracellular Matrix Interactions

Gopal, S., Multhaupt, H. A. B. & Couchman, J. R., 2020, Calcium Signaling. Islam, M. S. (ed.). 2nd ed. Switzerland: Springer, p. 1079-1102 24 p. (Advances in Experimental Medicine and Biology; vol. 1131).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

Mileto, S. J., Jardé, T., Childress, K. O., Jensen, J. L., Rogers, A. P., Kerr, G., Hutton, M. L., Sheedlo, M. J., Bloch, S. C., Shupe, J. A., Horvay, K., Flores, T., Engel, R., Wilkins, S., McMurrick, P. J., Lacy, D. B., Abud, H. E. & Lyras, D., 7 Apr 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 14, p. 8064-8073 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

Lam, D., Luu, P. L., Song, J. Z., Qu, W., Risbridger, G. P., Lawrence, M. G., Lu, J., Trau, M., Korbie, D., Clark, S. J., Pidsley, R. & Stirzaker, C., 22 Jun 2020, In : Clinical Epigenetics. 12, 1, 16 p., 90.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses

Pépin, G., De Nardo, D., Rootes, C. L., Ullah, T. R., Al-Asmari, S. S., Balka, K. R., Li, H-M., Quinn, K. M., Moghaddas, F., Chappaz, S., Kile, B. T., Morand, E. F., Masters, S. L., Stewart, C. R., Williams, B. R. G. & Gantier, M. P., 28 Jan 2020, In : mBio. 11, 1, 6 p., e03187-19.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Contemporaneity of australopithecus, paranthropus, and early homo erectus in South Africa

Herries, A. I. R., Martin, J. M., Leece, A. B., Adams, J. W., Boschian, G., Joannes-Boyau, R., Edwards, T. R., Mallett, T., Massey, J., Murszewski, A., Neubauer, S., Pickering, R., Strait, D. S., Armstrong, B. J., Baker, S., Caruana, M. V., Denham, T., Hellstrom, J., Moggi-Cecchi, J., Mokobane, S. & 7 others, Penzo-Kajewski, P., Rovinsky, D. S., Schwartz, G. T., Stammers, R. C., Wilson, C., Woodhead, J. & Menter, C., 3 Apr 2020, In : Science. 368, 6486, 19 p., eaaw7293.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

CRISP3 expression drives prostate cancer invasion and progression

Volpert, M., Furic, L., Hu, J., O'Connor, A. E., Rebello, R. J., Keerthikumar, S., Evans, J., Merriner, D. J., Pedersen, J., Risbridger, G. P., McIntyre, P. & O'Bryan, M. K., 1 Jul 2020, In : Endocrine-Related Cancer. 27, 7, p. 415-430 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Diet and cultural diversity in Neanderthals and modern humans from dental macrowear analysis

Fiorenza, L., Benazzi, S., Estalrrich, A. & Kullmer, O., 2020, Dental Wear in Evolutionary and Biocultural Contexts. Schmidt, C. W. & Watson, J. T. (eds.). 1st ed. London, UK: Academic Press, p. 39-72 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Disruption of genes associated with Charcot-Marie-Tooth type 2 lead to common behavioural, cellular and molecular defects in Caenorhabditis elegans

Soh, M. S., Cheng, X., Vijayaraghavan, T., Vernon, A., Liu, J. & Neumann, B., 15 Apr 2020, In : PLoS ONE. 15, 4, 29 p., e0231600.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Do cancer therapies damage the uterus and compromise fertility?

Griffiths, M. J., Winship, A. L. & Hutt, K. J., Mar 2020, In : Human Reproduction Update. 26, 2, p. 161-173 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Does antenatal betamethasone alter white matter brain development in growth restricted fetal sheep?

Sutherland, A. E., Yawno, T., Castillo-Melendez, M., Allison, B., Malhotra, A., Polglase, G. R., Cooper, L., Jenkin, G. & Miller, S., 30 Apr 2020, In : Frontiers in Cellular Neuroscience. 14, 12 p., 100.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Early impact of moderate preterm birth on the structure, function and gene expression of conduit arteries

Lombardo, P., Nguyen, V. B., Flores, T. J., Sutherland, M. R., Nitsos, I., Allison, B. J., Parkington, H., Tare, M., Harding, R., De Matteo, R., Schneider, M., Polglase, G. R. & Black, M. J., 1 Aug 2020, In : Experimental Physiology. 105, 8, p. 1256-1267 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Editorial: Immunomodulation of innate immune cells

Almeida, C. R., Bottazzi, B., De Nardo, D. & Lawlor, K. E., 11 Feb 2020, In : Frontiers in Immunology. 3 p., 101.

Research output: Contribution to journalEditorialOtherpeer-review

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Effects of preterm birth induced with or without exogenous glucocorticoids on the ovine glucose-insulin axis

Bansal, A., Alsweiler, J. M., Oliver, M. H., Jaquiery, A., Phua, H. H., Dragunow, M., de Matteo, R., Harding, J. E. & Bloomfield, F. H., 15 Jan 2020, (Accepted/In press) In : Journal of Developmental Origins of Health and Disease. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Experiences and lessons learned as a Chair of anatomy—An 18-year journey

Bertram, J. F., 8 Jan 2020, (Accepted/In press) In : Anatomical Record. 10 p.

Research output: Contribution to journalArticleOtherpeer-review

1 Citation (Scopus)

Exploring the impact of education on preclinical medical students' tolerance of uncertainty: A qualitative longitudinal study

Stephens, G. C., Rees, C. E. & Lazarus, M. D., 6 May 2020, (Accepted/In press) In : Advances in Health Sciences Education. 25 p.

Research output: Contribution to journalArticleResearchpeer-review

Forced Disruption of Anatomy Education in Australia and New Zealand: An Acute Response to the Covid-19 Pandemic

Pather, N., Blyth, P., Chapman, J. A., Dayal, M. R., Flack, N. A. M. S., Fogg, Q. A., Green, R. A., Hulme, A. K., Johnson, I. P., Meyer, A. J., Morley, J. W., Shortland, P. J., Štrkalj, G., Štrkalj, M., Valter, K., Webb, A. L., Woodley, S. J. & Lazarus, M. D., 18 Apr 2020, (Accepted/In press) In : Anatomical Sciences Education. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Functional genomics and gene-environment interaction highlight the complexity of Congenital Heart Disease caused by Notch pathway variants

Chapman, G., Moreau, J. L. M., Ip, E., Szot, J. O., Iyer, K. R., Shi, H., Yam, M. X., O’Reilly, V. C., Enriquez, A., Greasby, J. A., Alankarage, D., Martin, E. M. M. A., Hanna, B. C., Edwards, M., Monger, S., Blue, G. M., Winlaw, D. S., Ritchie, H. E., Grieve, S. M., Giannoulatou, E. & 2 others, Sparrow, D. B. & Dunwoodie, S. L., 15 Feb 2020, In : Human Molecular Genetics. 29, 4, p. 566-579 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Gelatin-based 3D microgels for in vitro T lineage cell generation

Suraiya, A. B., Hun, M. L., Truong, V. X., Forsythe, J. S. & Chidgey, A. P., 13 Apr 2020, In : ACS Biomaterials Science & Engineering. 6, 4, p. 2198-2208 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

Hun, M. L., Wong, K., Gunawan, J. R., Alsharif, A. A. M., Quinn, K. & Chidgey, A. P., 3 Mar 2020, In : Frontiers in Immunology. 11, 20 p., 302.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice

Chappaz, S., Law, C. W., Dowling, M. R., Carey, K. T., Lane, R. M., Ngo, L. H., Wickramasinghe, V. O., Smyth, G. K., Ritchie, M. E. & Kile, B. T., 14 Apr 2020, In : Blood Advances. 4, 7, p. 1270-1283 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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If Human Brain Organoids Are the Answer to Understanding Dementia, What Are the Questions?

Ooi, L., Dottori, M., Cook, A. L., Engel, M., Gautam, V., Grubman, A., Hernández, D., King, A. E., Maksour, S., Targa Dias Anastacio, H., Balez, R., Pébay, A., Pouton, C., Valenzuela, M., White, A. & Williamson, R., 13 Apr 2020, (Accepted/In press) In : Neuroscientist. 17 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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IFNB/interferon-β regulates autophagy via a MIR1-TBC1D15-RAB7 pathway

Ejlerskov, P., Rubinsztein, D. C. & Pocock, R., 2020, In : Autophagy. 16, 4, p. 767-769 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Induction of left ventricular hypoplasia by occluding the foramen ovale in the fetal lamb

Wong, F. Y., Veldman, A., Sasi, A., Teoh, M., Edwards, A., Chan, Y., Graupner, O., Enzensberger, C., Axt-Fliedner, R., Black, M. J. & Schranz, D., 1 Jan 2020, In : Scientific Reports. 10, 1, 11 p., 880.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo

Estermann, M. A., Williams, S., Hirst, C. E., Roly, Z. Y., Serralbo, O., Adhikari, D., Powell, D., Major, A. T. & Smith, C. A., 7 Apr 2020, In : Cell Reports. 31, 1, 19 p., 107491.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Introduction to a special issue on kidney development and disease

Sutherland, M. R., 2 Jul 2020, (Accepted/In press) In : Anatomical Record. 4 p.

Research output: Contribution to journalArticleOtherpeer-review

Knowing what's growing: Why ductal and intraductal prostate cancer matter

Lawrence, M. G., Porter, L. H., Clouston, D., Murphy, D. G., Frydenberg, M., Taylor, R. A. & Risbridger, G. P., 4 Mar 2020, In : Science Translational Medicine. 12, 533, 15 p., aaz0152.

Research output: Contribution to journalReview ArticleResearchpeer-review

Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019

Gillessen, S., Attard, G., Beer, T. M., Beltran, H., Bjartell, A., Bossi, A., Briganti, A., Bristow, R. G., Chi, K. N., Clarke, N., Davis, I. D., de Bono, J., Drake, C. G., Duran, I., Eeles, R., Efstathiou, E., Evans, C. P., Fanti, S., Feng, F. Y., Fizazi, K. & 52 others, Frydenberg, M., Gleave, M., Halabi, S., Heidenreich, A., Heinrich, D., Higano, C. T. S., Hofman, M. S., Hussain, M., James, N., Kanesvaran, R., Kantoff, P., Khauli, R. B., Leibowitz, R., Logothetis, C., Maluf, F., Millman, R., Morgans, A. K., Morris, M. J., Mottet, N., Mrabti, H., Murphy, D. G., Murthy, V., Oh, W. K., Ost, P., O'Sullivan, J. M., Padhani, A. R., Parker, C., Poon, D. M. C., Pritchard, C. C., Reiter, R. E., Roach, M., Rubin, M., Ryan, C. J., Saad, F., Sade, J. P., Sartor, O., Scher, H. I., Shore, N., Small, E., Smith, M., Soule, H., Sternberg, C. N., Steuber, T., Suzuki, H., Sweeney, C., Sydes, M. R., Taplin, M. E., Tombal, B., Türkeri, L., van Oort, I., Zapatero, A. & Omlin, A., Apr 2020, In : European Urology. 77, 4, p. 508-547 40 p.

Research output: Contribution to journalArticleOtherpeer-review

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12 Citations (Scopus)

Maternal hypoxia developmentally programs low podocyte endowment in male, but not female offspring

Gonçalves, G. D., Walton, S. L., Gazzard, S. E., van der Wolde, J., Mathias, P. C. F., Moritz, K. M., Cullen-McEwen, L. A. & Bertram, J. F., 27 Jan 2020, (Accepted/In press) In : Anatomical Record. 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Moderate episodic prenatal alcohol does not impact female offspring fertility in rats

McReight, E. K., Liew, S. H., Steane, S. E., Hutt, K. J., Moritz, K. M. & Akison, L. K., May 2020, In : Reproduction. 159, 5, p. 615-626 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Moderate prenatal ethanol exposure in the rat promotes kidney cell apoptosis, nephron deficits, and sex-specific kidney dysfunction in adult offspring

Akison, L. K., Probyn, M. E., Gray, S. P., Cullen-McEwen, L. A., Tep, K., Steane, S. E., Gobe, G. C., Wlodek, M. E., Bertram, J. F. & Moritz, K. M., 27 Jan 2020, (Accepted/In press) In : Anatomical Record. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Molecular signature of interleukin-22 in colon carcinoma cells and organoid models

Rudloff, I., Jardé, T., Bachmann, M., Elgass, K. D., Kerr, G., Engel, R., Richards, E., Oliva, K., Wilkins, S., McMurrick, P. J., Abud, H. E., Mühl, H. & Nold, M. F., Feb 2020, In : Translational Research. 216, p. 1-22 22 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Morphometric analysis of the hominin talus: Evolutionary and functional implications

Sorrentino, R., Carlson, K. J., Bortolini, E., Minghetti, C., Feletti, F., Fiorenza, L., Frost, S., Jashashvili, T., Parr, W., Shaw, C., Su, A., Turley, K., Wroe, S., Ryan, T. M., Belcastro, M. G. & Benazzi, S., May 2020, In : Journal of Human Evolution. 142, 21 p., 102747.

Research output: Contribution to journalArticleResearchpeer-review