Anatomy & Developmental Biology

Projects

Projects per year 2000 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2030

• 5 Curtailed
• 11 Not started
• 71 Active
• 442 Finished

Projects per year

Search results

• Active

  A Phase 3, Two-part, Randomized, Open-label, Adaptive Study Comparing BMS-986365 versus Investigator’s Choice of Therapy Comprising Either Docetaxel or Second Androgen Receptor Pathway Inhibitor (ARPI), in Participants with Metastatic Castration-resistant Prostrate Cancer (mCRPC) - rechARge

  Pook, D. (Primary Chief Investigator (PCI))

  7/04/25 → 6/06/27

  Project: Research

• Cilia biology: an emerging frontier.

  Mitchell, C., Smyth, I. & Davies, M.

  1/03/25 → 29/02/28

  Project: Research

• Scalable lentiviral screening of variants associated with kidney disease

  Combes, A. & Sun, B.

  1/03/25 → 30/09/26

  Project: Research

• Early Bipolar Androgen Therapy for Advanced Prostate Cancer

  Lawrence, M. (Primary Chief Investigator (PCI)), Selth, L. A. (Chief Investigator (CI)), Crumbaker, M. (Associate Investigator (AI)), Joshua, A. M. (Associate Investigator (AI)), Denmeade, S. (Chief Investigator (CI)), Taylor, R. (Associate Investigator (AI)), Ryan, A. (Associate Investigator (AI)), Lau, X. (Associate Investigator (AI)), Butler, L. M. (Associate Investigator (AI)), Goode, D. (Associate Investigator (AI)), Mills, I. G. (Associate Investigator (AI)) & Quezada Urban, R. (Associate Investigator (AI))

  1/01/25 → 31/12/28

  Project: Research

• A novel, therapeutically actionable, signalling axis in poor prognosis cancers

  Daly, R. (Primary Chief Investigator (PCI)), Ellisdon, A. (Associate Investigator (AI)), Lucet, I. (Associate Investigator (AI)), Stratton, M. (Associate Investigator (AI)), Tiganis, T. (Associate Investigator (AI)), Pajic, M. (Associate Investigator (AI)), Abud, H. (Associate Investigator (AI)), Shackleton, M. (Associate Investigator (AI)), Jarde, T. (Associate Investigator (AI)) & Swarbrick, A. (Associate Investigator (AI))

  1/01/25 → 31/12/28

  Project: Research

• Protecting fertility, healthy pregnancy and long-term endocrine function for cancer survivors after immunotherapy

  Winship, A. (Primary Chief Investigator (PCI)), Cui, W. (Chief Investigator (CI)), Stern, C. (Chief Investigator (CI)), Rozen, G. (Chief Investigator (CI)), Hutt, K. (Associate Investigator (AI)), La Gruta, N. (Associate Investigator (AI)), Jarde, T. (Associate Investigator (AI)), Fitzgerald, H. (Associate Investigator (AI)) & Marshall, S. (Associate Investigator (AI))

  1/01/25 → 31/12/28

  Project: Research

• A PHASE 3, RANDOMIZED, OPEN-LABEL STUDY OF PF-06821497 (MEVROMETOSTAT) IN COMBINATION WITH ENZALUTAMIDE COMPARED WITH ENZALUTAMIDE OR DOCETAXEL IN PARTICIPANTS WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER PREVIOUSLY TREATED WITH ABIRATERONE ACETATE (MEVPRO-1)

  Herbison, H. (Primary Chief Investigator (PCI))

  25/10/24 → 24/10/29

  Project: Research

• Identifying new combination therapies with testosterone for advanced prostate cancer

  Choo, N.

  1/10/24 → 1/10/25

  Project: Research

• Defining the contribution of inflammatory cytokines to oocyte maturation and quality

  Hutt, K. (Primary Chief Investigator (PCI)), Winship, A. (Chief Investigator (CI)), Stringer, J. (Chief Investigator (CI)), Green, M. (Associate Investigator (AI)), Vollenhoven, B. (Associate Investigator (AI)), Lliberos, C. (Associate Investigator (AI)) & Sarma, U. (Associate Investigator (AI))

  20/09/24 → 31/12/27

  Project: Research

• An Open-label, Randomized, Controlled Phase 3 Study of Disitamab Vedotin in Combination with Pembrolizumab Versus Chemotherapy in Subjects with Previously Untreated Locally Advanced or Metastatic Urothelial Carcinoma that Expresses HER2 (IHC 1+ and Greater)

  Pook, D. (Primary Chief Investigator (PCI))

  16/09/24 → 15/09/26

  Project: Research

• A Phase 1b, Open-Label, Multicenter Study Evaluating the Safety, Tolerability and Efficacy of Xaluritamig in Subjects with High-Risk Biochemical Recurrence of non- Metastatic Castration Sensitive Prostate Cancer After Definitive Therapy

  Pook, D. (Primary Chief Investigator (PCI))

  13/09/24 → 12/09/26

  Project: Research

• From foraging to farming. Human adaptations during major transitions

  Fiorenza, L. (Primary Chief Investigator (PCI)), Benazzi, S. (Partner Investigator (PI)) & Sarig, R. (Partner Investigator (PI))

  Australian Research Council (ARC)

  1/08/24 → 31/07/27

  Project: Research

• A Phase 3, Randomized, Open-label Study of MK-5684 Versus Alternative Abiraterone Acetate or Enzalutamide in Participants with Metastatic Castration-resistant Prostate Cancer (mCRPC) That Progressed On or After Prior Treatment with One Nextgeneration Hormonal Agent (NHA)

  Herbison, H. (Primary Chief Investigator (PCI)) & Pook, D. (Primary Chief Investigator (PCI))

  16/07/24 → 15/07/29

  Project: Research

• Development of Co-designed Digital Exemplars to Enhance Health Profession Readiness for Safe and Effective Care of People with Disability

  Lalor, A. (Primary Chief Investigator (PCI)), Brand, G. (Chief Investigator (CI)), Farlie, M. (Chief Investigator (CI)), Gosling, C. (Chief Investigator (CI)), Morgan, P. (Chief Investigator (CI)), Petrakis, M. (Chief Investigator (CI)), Lazarus, M. (Chief Investigator (CI)), Archer, J. (Chief Investigator (CI)) & Lindley, J. (Chief Investigator (CI))

  Monash University

  1/07/24 → 31/12/25

  Project: Research

• Studying communication between cancer-associated fibroblasts and breast cancer cells to identify druggable vulnerabilities

  Jarde, T. (Primary Chief Investigator (PCI)), Richardson, G. E. (Chief Investigator (CI)), Daly, R. (Chief Investigator (CI)), Merino, D. (Chief Investigator (CI)), Leung, D. (Chief Investigator (CI)), Fennell, L. (Chief Investigator (CI)), Abud, H. (Associate Investigator (AI)), Ingham, S. (Associate Investigator (AI)) & Port, M. (Associate Investigator (AI))

  6/04/24 → 5/04/27

  Project: Research

• A PHASE I, OPEN-LABEL, MULTICENTER, DOSE-ESCALATION AND EXPANSION STUDY EVALUATING THE SAFETY, PHARMACOKINETICS, AND ACTIVITY OF RO7656594 IN PATIENTS WITH ADVANCED OR METASTATIC PROSTATE CANCER

  Pook, D. (Primary Chief Investigator (PCI))

  2/04/24 → 1/04/29

  Project: Research

• New insights into female reproductive tract formation and tubulogenesis.

  Smith, C. (Primary Chief Investigator (PCI)) & Behringer, R. R. (Partner Investigator (PI))

  27/03/24 → 26/03/27

  Project: Research

• A randomized, double-blind, placebo-controlled Phase 3 study of darolutamide plus androgen deprivation therapy (ADT) compared with placebo plus ADT in patients with high-risk biochemical recurrence (BCR) of prostate cancer

  Pook, D. (Primary Chief Investigator (PCI))

  20/03/24 → 20/03/26

  Project: Research

• COX2-driven T cell suppression in the colorectal cancer microenvironment

  Fletcher, A. (Primary Chief Investigator (PCI)), Wilkins, S. (Chief Investigator (CI)), McMurrick, P. (Associate Investigator (AI)), Abud, H. (Associate Investigator (AI)), Daly, R. (Associate Investigator (AI)), Nefzger, C. (Associate Investigator (AI)), Georges, C. (Associate Investigator (AI)) & Asghari-Jafarabadi, M. (Associate Investigator (AI))

  1/01/24 → 31/12/28

  Project: Research

• Bite’s evolution: a biomechanical study of Pleistocene humans in Europe

  Martín-Francés , L. (Primary Chief Investigator (PCI)), Fiorenza, L. (Supervisor), Martinón Torres, M. (Supervisor) & Arsuaga Ferreras, J. L. (Supervisor)

  European Commission

  1/01/24 → 31/12/25

  Project: Research

• Understanding and mitigating the off-target impacts of immunotherapy on female reproductive and endocrine health

  Winship, A. (Primary Chief Investigator (PCI))

  1/01/24 → 13/03/30

  Project: Research

• A Multinational, Multicenter, Prospective, Randomized Controlled, Open Label Phase 3 Study with Best Standard of Care with and without 177Lu-DOTA-Rosopatamab for Patients with PSMA Expressing Metastatic Castration-Resistant Prostate Cancer Progressing Despite Prior Treatment with A Novel Androgen AXIS Drug

  Liow, E. (Primary Chief Investigator (PCI)) & Pook, D. (Primary Chief Investigator (PCI))

  1/12/23 → 30/11/28

  Project: Research

• Mechanistic analyses of EHD proteins in cellular physiology

  Pucadyil, T. J. (Primary Chief Investigator (PCI)), Arumugam, S. (Chief Investigator (CI)) & Srivastava, A. (Chief Investigator (CI))

  1/10/23 → 30/09/28

  Project: Research

• Surface coatings for directed differentiation for iPSCs to T-cells

  Meagher, L. (Primary Chief Investigator (PCI)), Heng, T. (Chief Investigator (CI)), Boyd, R. L. (Partner Investigator (PI)) & Ruka, D. (Project Manager)

  26/06/23 → 26/12/26

  Project: Research

• A Phase 2, Open-Label Study of Vobramitamab Duocarmazine in Participants with Metastatic Castration-Resistant Prostate Cancer and Other Solid Tumors(TAMARACK)

  Pook, D. (Primary Chief Investigator (PCI))

  7/06/23 → 6/06/25

  Project: Research

• MitoHOPE: Introducing Mitochondrial Donation in AustraliaL The MitoHOPE (Healthy Outcomes Pilot and Evaluation) Program

  Carroll, J. (Primary Chief Investigator (PCI)), Herbert, M. (Chief Investigator (CI)), Christodoulou, J. (Chief Investigator (CI)), Thorburn, D. R. (Chief Investigator (CI)), Mills, C. (Chief Investigator (CI)), Zander-Fox, D. L. (Chief Investigator (CI)), Robker, R. (Chief Investigator (CI)), Rombauts, L. (Chief Investigator (CI)), Sallevelt, S. (Chief Investigator (CI)), Ludlow, K. (Chief Investigator (CI)), Coman, D. J. (Chief Investigator (CI)), Ellaway, C. (Chief Investigator (CI)), Mackey, D. A. (Chief Investigator (CI)), Delatycki, M. B. (Chief Investigator (CI)), Yau, W. Y. (Chief Investigator (CI)), Tchan, M. C. (Chief Investigator (CI)), Long, J. C. (Chief Investigator (CI)), Hardy, T. (Chief Investigator (CI)), Adhikari, D. (Chief Investigator (CI)), Choudhary, M. (Chief Investigator (CI)), Hyslop, L. A. (Chief Investigator (CI)), Mann, J. (Chief Investigator (CI)), Ryan, M. (Chief Investigator (CI)), Hodges, R. (Chief Investigator (CI)), Hui, L. (Chief Investigator (CI)), Kamien, B. A. (Chief Investigator (CI)), Mallett, A. J. (Chief Investigator (CI)), Semsarian, C. (Chief Investigator (CI)), Wallis, M. J. (Chief Investigator (CI)), Wall, M. (Chief Investigator (CI)), Zoungas, S. (Chief Investigator (CI)), Goranitis, I. (Chief Investigator (CI)), Gyngell, C. (Chief Investigator (CI)), Hammarberg, K. (Chief Investigator (CI)), Sparrow, R. (Chief Investigator (CI)), Warren, N. (Chief Investigator (CI)), Fahey, M. (Chief Investigator (CI)), Stutterd, C. A. (Associate Investigator (AI)), Schweitzer, D. (Associate Investigator (AI)), McGillivray, G. (Associate Investigator (AI)), Savulescu, J. (Associate Investigator (AI)), Panetta, J. (Associate Investigator (AI)), Kava, M. P. (Associate Investigator (AI)), Freckmann, M.-L. (Associate Investigator (AI)), Lynch, M. (Associate Investigator (AI)), Lamont, P. J. (Associate Investigator (AI)), Scott, R. (Associate Investigator (AI)), Ware, T. (Associate Investigator (AI)), Mowat, D. (Associate Investigator (AI)), Jones, K. J. (Associate Investigator (AI)), Green, S. (Associate Investigator (AI)), Wolfe, R. (Associate Investigator (AI)), Hackett, A. (Associate Investigator (AI)), Bratkovic, D. (Associate Investigator (AI)), Horton, A. (Associate Investigator (AI)) & Blok, R. (Project Manager)

  Monash University – Internal Faculty Contribution, Australian Genomics, Centenary Institute of Cancer Medicine & Cell Biology, James Cook University, Lyons Eye Institute Limited, Macquarie University, Murdoch Children's Research Institute, Australian Mitochondrial Disease Foundation Limited (trading as Mito Foundation), Monash IVF Group Limited, Perron Institute for Neurological and Translational Science Limited, Queensland Children's Hosptial , Tasmanian Clinical Genetics Service, University of Adelaide, Victorian Assisted Reproductive Treatment Authority (VARTA) (Victoria), Women's and Children's Health Care Network Incorporated, Western Sydney Local Health District (WSLHD)

  1/06/23 → 31/05/29

  Project: Research

• Development of novel mRNA products for clinical trials

  Pouton, C., Beilharz, T., Carroll, J., Porter, C., Al-Wassiti, H., Davidovich, C., Johnston, A. & Trevaskis, N.

  10/05/23 → 2/10/28

  Project: Research

• Imaging mammalian organogenesis with adaptive optics

  Combes, A. (Primary Chief Investigator (PCI)), Nunez-Iglesias, J. (Chief Investigator (CI)) & Royer, L. (Partner Investigator (PI))

  21/04/23 → 20/04/26

  Project: Research

• PET-MET: Retrospective analysis of the ENZAMET cohort - Utility of PSMA PET scan quantitation and CT radiomics as prognostic and predictive biomarkers

  Pook, D. (Primary Chief Investigator (PCI))

  16/03/23 → 15/03/28

  Project: Research

• How are sperm mitochondria eliminated after fertilisation

  Carroll, J. & Adhikari, D.

  Australian Research Council (ARC)

  15/03/23 → 14/03/26

  Project: Research

• An observational study of Cxbladder performance for the detection of urothelial carcinoma in patients presenting with haematuria

  Ranasinghe, W. (Primary Chief Investigator (PCI))

  3/03/23 → 2/03/28

  Project: Research

• An Observational Study of Cxbladder Monitoring for Recurrence of Urothelial Carcinoma in Intermediate and High-Risk Patients

  Ranasinghe, W. (Primary Chief Investigator (PCI))

  3/03/23 → 2/03/28

  Project: Research

• Preventing a nephron deficit in premature offspring

  Bertram, J. (Primary Chief Investigator (PCI)), Cullen-McEwen, L. (Chief Investigator (CI)), Charlton, J. (Chief Investigator (CI)), Simpson, S. J. (Associate Investigator (AI)), Solon-Biet, S. (Associate Investigator (AI)), Rose, A. (Associate Investigator (AI)), Schittenhelm, R. (Associate Investigator (AI)), Barlow, C. (Associate Investigator (AI)), Combes, A. (Associate Investigator (AI)), Tan, K. (Associate Investigator (AI)), Johnstone, L. (Associate Investigator (AI)), Wlodek, M. (Associate Investigator (AI)) & Stanford, K. I. (Associate Investigator (AI))

  1/01/23 → 31/12/26

  Project: Research

• Development of a precision oncology program focused on a novel therapeutic target in triple negative breast cancer

  Daly, R. (Primary Chief Investigator (PCI)), Chueh, A. (Chief Investigator (CI)), Abud, H. (Chief Investigator (CI)), Jarde, T. (Chief Investigator (CI)), Loi, S. (Chief Investigator (CI)), Tiganis, T. (Associate Investigator (AI)), Swarbrick, A. (Associate Investigator (AI)), Rosenbluh, S. (Associate Investigator (AI)), Nguyen, L. (Associate Investigator (AI)), Song, J. (Associate Investigator (AI)) & Nekkalapudi, N. (Associate Investigator (AI))

  National Breast Cancer Foundation

  1/01/23 → 31/12/25

  Project: Research

• Wnt Signalling in Oligodendroglia: A missing link in MS neuroinflammation

  Gonsalvez, D. (Primary Chief Investigator (PCI)), Barton, S. (Chief Investigator (CI)), Rutar, M. (Chief Investigator (CI)), Mills, S. (Chief Investigator (CI)) & Govier-Cole, A. (Chief Investigator (CI))

  1/01/23 → 31/12/26

  Project: Research

• Deconvoluting the complexity of lipid metabolism for prostate cancer therapy

  Taylor, R. (Primary Chief Investigator (PCI)), Watt, M. (Chief Investigator (CI)) & Pook, D. (Chief Investigator (CI))

  1/01/23 → 31/12/25

  Project: Research

• Defining how signalling pathways cooperate to regulate organ size

  Harvey, K.

  1/01/23 → 31/12/25

  Project: Research

• Understanding why mammalian eggs have so much mitochondrial DNA

  Adhikari, D. & Carroll, J.

  Australian Research Council (ARC)

  1/01/23 → 31/12/25

  Project: Research

• Developing new therapeutic approaches against advanced bowel cancer

  Jarde, T. (Primary Chief Investigator (PCI)), Abud, H. (Associate Investigator (AI)), McMurrick, P. (Associate Investigator (AI)), Woods, S. (Associate Investigator (AI)), McKeown, S. (Associate Investigator (AI)), Stansen, G. (Associate Investigator (AI)) & Archer, S. (Associate Investigator (AI))

  1/01/23 → 31/12/26

  Project: Research

• Uncovering novel mechanisms of treatment resistance in lethal colorectal cancers

  Abud, H. (Primary Chief Investigator (PCI)), Engel, R. (Chief Investigator (CI)), McMurrick, P. (Chief Investigator (CI)), Schittenhelm, R. (Chief Investigator (CI)), Lum, C. D. R. (Chief Investigator (CI)) & Archer, S. (Chief Investigator (CI))

  1/01/23 → 31/12/25

  Project: Research

• Characterization of the Germline Regulatory Landscape

  Pocock, R. (Primary Chief Investigator (PCI)), Cao, W. (Chief Investigator (CI)), Fan, Q. (Chief Investigator (CI)), Hutt, K. (Associate Investigator (AI)), Gopal, S. (Associate Investigator (AI)), Schittenhelm, R. (Associate Investigator (AI)), Hobbs, R. (Associate Investigator (AI)), Archer, S. (Associate Investigator (AI)) & Coutts, S. (Associate Investigator (AI))

  1/01/23 → 31/12/27

  Project: Research

• Using BAT to aBATe lethal prostate cancer

  Lawrence, M. (Primary Chief Investigator (PCI)), Frydenberg, M. (Chief Investigator (CI)), Ramm, S. (Chief Investigator (CI)) & Joshua, A. (Chief Investigator (CI))

  1/01/23 → 31/12/25

  Project: Research

• A Phase II, Multicenter, Randomized, Open Label, Parallel-Arm, Umbrella Study of Avelumab (MSB0010718C) in Combination with Other Anti-Tumor Agents as a Maintenance Treatment in Participants with Locally Advanced or Metastatic Urothelial Carcinoma Whose Disease Did Not Progress with First Line Platinum-Containing Chemotherapy

  Pook, D. (Chief Investigator (CI)) & Herbison, H. (Primary Chief Investigator (PCI))

  17/10/22 → 16/10/27

  Project: Research

• Improving efficacy of CAR T cell therapies for solid tumors

  Risbridger, G. (Primary Chief Investigator (PCI)), Trapani, J. A. (Partner Investigator (PI)), Meagher, L. (Chief Investigator (CI)) & Ruka, D. (Project Manager)

  1/09/22 → 12/01/26

  Project: Research

• The Victorian Pre-clinical mRNA Innovation Incubator (VPMII)

  Porter, C. (Primary Chief Investigator (PCI)), Pouton, C. (Chief Investigator (CI)), Carroll, J. (Chief Investigator (CI)), Beilharz, T. (Chief Investigator (CI)), Purcell, D. F. J. (Chief Investigator (CI)), Caruso, F. (Chief Investigator (CI)), Trevaskis, N. (Chief Investigator (CI)), Johnston, A. (Chief Investigator (CI)), Davidovich, C. (Chief Investigator (CI)) & Knott, G. (Chief Investigator (CI))

  23/06/22 → 22/06/25

  Project: Research

• TRIAGE: A disease agnostic computational and modelling platform to accelerate variant classification

  Palpant, N. J. (Primary Chief Investigator (PCI)), Mallett, A. J. (Chief Investigator (CI)), Yanes, T. (Chief Investigator (CI)), Shah, S. (Chief Investigator (CI)), Stark, Z. L. (Chief Investigator (CI)), McGaughran, J. (Chief Investigator (CI)), Combes, A. (Chief Investigator (CI)), Boden, M. (Chief Investigator (CI)), Atherton, J. (Chief Investigator (CI)), Fatkin, D. (Chief Investigator (CI)), Ingles, J. (Chief Investigator (CI)), Bagnall, R. (Chief Investigator (CI)), Hill, A. (Chief Investigator (CI)), Bryson-Richardson, R. (Chief Investigator (CI)), Harvey, R. P. (Chief Investigator (CI)), Cheetham, S. W. (Associate Investigator (AI)), Nefzger, C. (Associate Investigator (AI)), Giannoulatou, E. (Associate Investigator (AI)), Vandenberg, J. I. (Associate Investigator (AI)), Zeng, J. (Associate Investigator (AI)), Rodgers, J. (Associate Investigator (AI)) & Foster, M. (Associate Investigator (AI))

  Monash University – Internal University Contribution

  1/06/22 → 31/05/25

  Project: Research

• Are Oligodendrocytes the Missing Link in Amyotrophic Lateral Sclerosis

  Barton, S. (Primary Chief Investigator (PCI)) & Gonsalvez, D. (Chief Investigator (CI))

  6/02/22 → 31/12/26

  Project: Research

• Reprograming of different cell types into podocytes

  Polo, J. (Primary Chief Investigator (PCI)), Bertram, J. (Chief Investigator (CI)), Rackham, O. (Partner Investigator (PI)), Meagher, L. (Chief Investigator (CI)) & Ruka, D. (Project Manager)

  3/01/22 → 12/01/26

  Project: Research

• Does Chlamydia infection damage the ovary and compromise fertility?

  Hutt, K. (Primary Chief Investigator (PCI)), Beagley, K. (Chief Investigator (CI)), Homer, H. A. (Associate Investigator (AI)) & Carey, A. (Associate Investigator (AI))

  1/01/22 → 31/12/26

  Project: Research

• Deciphering incomplete penetrance of subfertility

  Crismani, W. (Primary Chief Investigator (PCI)), Stringer, J. (Chief Investigator (CI)) & Hoffmann, E. (Chief Investigator (CI))

  1/01/22 → 31/12/25

  Project: Research