Monash Micro Imaging

    Ian Harper (Manager), Stephen Firth (Manager)Alex Fulcher (Operator)Oleks Chernyavskiy (Operator)Margaret Rzeszutek (Other)David Potter (Manager)Volker Hilsenstein (Operator)Juan Nunez-Iglesias (Other), Stephen Cody (Manager)Irena Carmichael (Operator)Betty Kouskousis (Other), Chad Johnson (Operator)Sarah Creed (Manager)Giulia Ballerin (Operator)

Facility/equipment: Facility

  • Location

    15 Innovation Walk Monash University Victoria 3800

    Australia

Research Output

2017

Expression patterns of HENMT1 and PIWIL1 in human testis: Implications for transposon expression

Hempfling, AL., Lim, SL., Adelson, DL., Evans, J., O'Connor, AE., Qu, ZP., Kliesch, S., Weidner, W., O'Bryan, MK. & Bergmann, M., 1 Oct 2017, In : Reproduction. 154, p. 363-374 12 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Foxp3+ Tregs are recruited to the retina to repair pathological angiogenesis

Deliyanti, D., Talia, D. M., Zhu, T., Maxwell, M. J., Agrotis, A., Jerome, J. R., Hargreaves, E. M., Gerondakis, S., Hibbs, M. L., Mackay, F. & Wilkinson-Berka, J. L., 1 Dec 2017, In : Nature Communications. 8, 1, 12 p., 748.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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19 Citations (Scopus)

Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes

Chan, A. L., La, H. M., Legrand, J. M. D., Mäkelä, J. A., Eichenlaub, M., De Seram, M., Ramialison, M. & Hobbs, R. M., 12 Sep 2017, In : Stem Cell Reports. 9, 3, p. 956-971 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury

Zhu, D., Tan, J., Maleken, A. S., Muljadi, R., Chan, S. T., Lau, S. N., Elgass, K., Leaw, B., Mockler, J., Chambers, D., Leeman, K. T., Kim, C. F., Wallace, E. M. & Lim, R., 10 Nov 2017, In : Stem Cell Research and Therapy. 8, 1, 24 p., 257.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

INPP5E regulates phosphoinositide-dependent cilia transition zone function

Dyson, J. M., Conduit, S. E., Feeney, S. J., Hakim, S., DiTommaso, T., Fulcher, A. J., Sriratana, A., Ramm, G., Horan, K. A., Gurung, R., Wicking, C., Smyth, I. & Mitchell, C. A., 2 Jan 2017, In : Journal of Cell Biology. 216, 1, p. 247-263 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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36 Citations (Scopus)

Interactome of the inhibitory isoform of the nuclear transporter Importin 13

Fatima, S., Wagstaff, K. M., Lieu, K. G., Davies, R. G., Tanaka, S. S., Yamaguchi, Y. L., Loveland, K. L., Tam, P. P. L. & Jans, D. A., 1 Mar 2017, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 3, p. 546-561 16 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Microfluidic Encapsulation of Human Mesenchymal Stem Cells for Articular Cartilage Tissue Regeneration

Li, F., Truong, V. X., Thissen, H., Frith, J. E. & Forsythe, J. S., 15 Mar 2017, In : ACS Applied Materials & Interfaces. 9, 10, p. 8589-8601 13 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

miR-378 reduces mesangial hypertrophy and kidney tubular fibrosis via MAPK signalling

Wang, B., Yao, K., Wise, A. F., Lau, R., Shen, H-H., Tesch, G. H. & Ricardo, S. D., 2017, In : Clinical Science. 131, 5, p. 411-423 13 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Mitochondrial protein p32/HAPB1/gC1qR/C1qbp is required for efficient respiratory syncytial virus production

Hu, M., Li, H-M., Bogoyevitch, M. A. & Jans, D. A., 5 Aug 2017, In : Biochemical and Biophysical Research Communications. 489, 4, p. 460-465 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Mutations in the Katnb1 gene cause left-right asymmetry and heart defects

Furtado, M. B., Merriner, D. J., Berger, S., Rhodes, D., Jamsai, D. & O'Bryan, M. K., Dec 2017, In : Developmental Dynamics. 246, 12, p. 1027-1035 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Native thymic extracellular matrix improves in vivo thymic organoid T cell output, and drives in vitro thymic epithelial cell differentiation

Hun, M., Barsanti, M., Wong, K., Ramshaw, J., Werkmeister, J. & Chidgey, A. P., Feb 2017, In : Biomaterials. 118, p. 1-15 15 p., 145253.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia

Yuan, Y., Alwis, I., Wu, M. C. L., Kaplan, Z., Ashworth, K., Bark, D., Pham, A., McFadyen, J., Schoenwaelder, S. M., Josefsson, E. C., Kile, B. T. & Jackson, S. P., 27 Sep 2017, In : Science Translational Medicine. 9, 409, 14 p., eaam5861.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Nuclear localization and secretion competence are conserved among henipavirus matrix proteins

McLinton, E. C., Wagstaff, K. M., Lee, A., Moseley, G. W., Marsh, G. A., Wang, L-F., Jans, D. A., Lieu, K. G. & Netter, H. J., 1 Apr 2017, In : Journal of General Virology. 98, 4, p. 563-576 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Optical projection tomography as a novel method to visualize and quantitate whole-brain patterns of cell proliferation in the adult zebrafish brain

Lindsey, B. W. & Kaslin, J., 1 Dec 2017, In : Zebrafish. 14, 6, p. 574-577 4 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Phosphatidylserine save-me signals drive functional recovery of severed axons in Caenorhabditis elegans

Abay, Z. C., Wong, M. Y-Y., Teoh, J-S., Vijayaraghavan, T., Hilliard, M. A. & Neumann, B., 21 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10196-E10205 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

Phosphorylation of Lbx1 controls lateral myoblast migration into the limb

Masselink, W., Masaki, M., Sieiro, D., Marcelle, C. & Currie, P. D., 15 Oct 2017, In : Developmental Biology. 430, 2, p. 302-309 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling

Furtado, M. B., Wilmanns, J. C., Chandran, A., Perera, J., Hon, O., Biben, C., Willow, T. J., Nim, H. T., Kaur, G., Simonds, S., Wu, Q., Willians, D., Salimova, E., Plachta, N., Denegre, J. M., Murray, S. A., Fatkin, D., Cowley, M., Pearson, J. T., Kaye, D. & 4 others, Ramialison, M., Harvey, R. P., Rosenthal, N. A. & Costa, M. W., 23 Mar 2017, In : JCI Insight. 2, 6, p. e88271 18 p., e88271.

Research output: Contribution to journalArticleResearch

5 Citations (Scopus)

PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

Prokopuk, L., Stringer, J. M., Hogg, K., Elgass, K. D. & Western, P. S., 20 Feb 2017, In : Epigenetics and Chromatin. 10, 1, 20 p., 7.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

SCA-1 labels a subset of estrogen-responsive bipotential repopulating cells within the CD24+ CD49fhi mammary stem cell-enriched compartment

Dall, G. V., Vieusseux, J. L., Korach, K. S., Arao, Y., Hewitt, S. C., Hamilton, K. J., Dzierzak, E., Boon, W. C., Simpson, E. R., Ramsay, R. G., Stein, T., Morris, J. S., Anderson, R. L., Risbridger, G. P. & Britt, K. L., 14 Feb 2017, In : Stem Cell Reports. 8, 2, p. 417-431 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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14 Citations (Scopus)

Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin

Niego, B., Lee, N., Larsson, P., De Silva, T. M., Au, A. E. L., McCutcheon, F. & Medcalf, R. L., 1 May 2017, In : PLoS ONE. 12, 5, 21 p., e0177332.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Short-term high-fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity

Balland, E. & Cowley, M. A., 1 Oct 2017, In : Journal of Neuroendocrinology. 29, 10, 7 p., e12504.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Qin, C. X., May, L. T., Li, R., Cao, N., Rosli, S., Deo, M., Alexander, A. E., Horlock, D., Bourke, J. E., Yang, Y. H., Stewart, A. G., Kaye, D. M., Du, X. J., Sexton, P. M., Christopoulos, A., Gao, X. M. & Ritchie, R. H., 7 Feb 2017, In : Nature Communications. 8, 13 p., 14232.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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36 Citations (Scopus)

Small size at birth predicts decreased cardiomyocyte number in the adult ovine heart

Vranas, S., Heinemann, G. K., Liu, H., De Blasio, M. J., Owens, J. A., Gatford, K. L. & Black, M. J., Oct 2017, In : Journal of Developmental Origins of Health and Disease. 8, 5, p. 618-625 8 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association

Patel, O., Griffin, M. D. W., Panjikar, S., Dai, W., Ma, X., Chan, H., Zheng, C., Kropp, A., Murphy, J. M., Daly, R. J. & Lucet, I. S., 1 Dec 2017, In : Nature Communications. 8, 1, 15 p., 1157.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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14 Citations (Scopus)

Tailored emulsion-templated porous polymer scaffolds for iPSC-derived human neural precursor cell culture

Murphy, A. R., Ghobrial, I., Jamshidi, P., Laslett, A., O'Brien, C. M. & Cameron, N. R., 20 Nov 2017, In : Polymer Chemistry. 8, 43, p. 6617-6627 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Targeting activated platelets: A unique and potentially universal approach for cancer imaging

Yap, M. L., McFadyen, J. D., Wang, X., Zia, N. A., Hohmann, J. D., Ziegler, M., Yao, Y., Pham, A., Harris, M., Donnelly, P. S., Hogarth, P. M., Pietersz, G. A., Lim, B. & Peter, K., 2017, In : Theranostics. 7, 10, p. 2565-2574 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

Charnaud, S. C., Dixon, M. W. A., Nie, C. Q., Chappell, L., Sanders, P. R., Nebl, T., Hanssen, E., Berriman, M., Chan, J., Blanch, A. J., Beeson, J. G., Rayner, J. C., Przyborski, J. M., Tilley, L., Crabb, B. S. & Gilson, P. R., 1 Jul 2017, In : PLoS ONE. 12, 7, 22 p., e0181656.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

The middle fragment of Helicobacter pylori CagA induces Actin rearrangement and triggers its own uptake into gastric epithelial cells

Tohidpour, A., Gorrell, R. J., Roujeinikova, A. & Kwok, T., 1 Aug 2017, In : Toxins. 9, 8, 16 p., 237.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction

Sharma, A., Rizky, L., Stefanovic, N., Tate, M., Ritchie, R. H., Ward, K. W. & de Haan, J. B., 3 Mar 2017, In : Cardiovascular Diabetology. 16, 1, 13 p., 33.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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39 Citations (Scopus)

The Role of Mesolimbic Reward Neurocircuitry in Prevention and Rescue of the Activity-Based Anorexia (ABA) Phenotype in Rats

Foldi, C. J., Milton, L. K. & Oldfield, B. J., 21 Mar 2017, In : Neuropsychopharmacology. 42, 12, p. 2292-2300 9 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

The Unique Paired Retinal Vessels of the Gray Short-Tailed Opossum (Monodelphis domestica) and Their Relationship to Astrocytes and Microglial Cells

McMenamin, P. G., Naranjo Golborne, C., Chen, X., Wheaton, B. & Dando, S., Aug 2017, In : Anatomical Record. 300, 8, p. 1391-1400 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Topography of claustrum and insula projections to medial prefrontal and anterior cingulate cortices of the common marmoset (Callithrix jacchus)

Reser, D. H., Majka, P., Snell, S., Chan, J. M. H., Watkins, K., Worthy, K., Del Mar Quiroga, M. & Rosa, M. G. P., 15 Apr 2017, In : The Journal of Comparative Neurology. 525, 6, p. 1421-1441 21 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Versatile Bioorthogonal Hydrogel Platform by Catalyst-Free Visible Light Initiated Photodimerization of Anthracene

Truong, V. X., Li, F. & Forsythe, J. S., 18 Jul 2017, In : ACS Macro Letters. 6, 7, p. 657-662 6 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)
2016

Accessory subunits are integral for assembly and function of human mitochondrial complex I

Stroud, D. A., Surgenor, E. E., Formosa, L. E., Reljic, B., Frazier, A. E., Dibley, M. G., Osellame, L. D., Stait, T., Beilharz, T. H., Thorburn, D. R., Salim, A. & Ryan, M. T., 6 Oct 2016, In : Nature. 538, 7623, p. 123-126 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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120 Citations (Scopus)

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

Bhuiyan, M. S., Ellett, F., Murray, G. L., Kostoulias, X., Cerqueira, G. M., Schulze, K. E., Mahamad Maifiah, M. H., Li, J., Creek, D. J., Lieschke, G. J. & Peleg, A. Y., 23 Aug 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 34, p. 9599-9604 6 p., 1523116113.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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39 Citations (Scopus)

An activated form of ADAM10 is tumor selective and regulates cancer stem-like cells and tumor growth

Atapattu, L., Saha, N., Chheang, C., Eissman, M. F., Xu, K., Vail, M. E., Hii, L., Llerena, C., Liu, Z., Horvay, K., Abud, H. E., Kusebauch, U., Moritz, R. L., Ding, B-S., Cao, Z., Rafii, S., Ernst, M., Scott, A. M., Nikolov, D. B., Lackmann, M. & 1 others, Janes, P. W., 8 Aug 2016, In : Journal of Experimental Medicine. 213, 9, p. 1741-1757 17 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Antimalarial activity of novel 4-cyano-3-methylisoquinoline inhibitors against Plasmodium falciparum: Design, synthesis and biological evaluation

Buskes, M. J., Harvey, K. L., Richards, B. J., Kalhor, R., Christoff, R. M., Gardhi, C. K., Littler, D. R., Cope, E. D., Prinz, B., Weiss, G. E., O'Brien, N. J., Crabb, B. S., Deady, L. W., Gilson, P. R. & Abbott, B. M., 22 Apr 2016, In : Organic and Biomolecular Chemistry. 14, 20, p. 4617-4639 23 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

A somitic contribution to the apical ectodermal ridge is essential for fin formation

Masselink, W., Cole, N. J., Fenyes, F., Berger, S., Sonntag, C., Wood, A., Nguyen, P. D., Cohen, N., Knopf, F., Weidinger, G., Hall, T. E. & Currie, P. D., 28 Jul 2016, In : Nature. 535, 7613, p. 542-546 5 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

Nguyen, T. N., Padman, B. S., Usher, J., Oorschot, V., Ramm, G. & Lazarou, M., 18 Nov 2016, In : Journal of Cell Biology. 215, 6, p. 857-874 18 p.

Research output: Contribution to journalArticleResearchpeer-review

193 Citations (Scopus)

Brinp1-/- mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density

Berkowicz, S. R., Featherby, T. J., Qu, Z., Giousoh, A., Borg, N. A., Heng, J. I., Whisstock, J. C. & Bird, P. I., 31 Mar 2016, In : Molecular Autism. 7, 22, 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo

Sampson, A. K., Irvine, J. C., Shihata, W. A., Dragoljevic, D., Lumsden, N., Huet, O., Barnes, T., Unger, T., Steckelings, U. M., Jennings, G. L., Widdop, R. E. & Chin-Dusting, J. P. F., 1 Feb 2016, In : British Journal of Pharmacology. 173, 4, p. 729-740 12 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles

Leong, Y. A., Chen, Y., Ong, H. S., Wu, D., Man, K., Deleage, C., Minnich, M., Meckiff, B. J., Wei, Y., Hou, Z., Zotos, D., Fenix, K. A., Atnerkar, A., Preston, S., Chipman, J. G., Beilman, G. J., Allison, C. C., Sun, L., Wang, P., Xu, J. & 10 others, Toe, J. G., Lu, H. K., Tao, Y., Palendira, U., Dent, A. L., Landay, A. L., Pellegrini, M., Comerford, I., Lewin, S. R. & Yu, D., 3 Aug 2016, In : Nature Immunology. 17, 10, p. 1187-1196 10 p.

Research output: Contribution to journalArticleResearchpeer-review

155 Citations (Scopus)

Development of the cellular immune system of Drosophila requires the membrane attack complex/perforin-like protein Torso-like

Forbes-Beadle, L., Crossman, T., Johnson, T. K., Burke, R., Warr, C. G. & Whisstock, J. C., 1 Oct 2016, In : Genetics. 204, 2, p. 675-681 7 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Dynamic nucleolar targeting of dengue virus polymerase NS5 in response to extracellular pH

Fraser, J. E., Rawlinson, S. M., Heaton, S. M. & Jans, D. A., Jun 2016, In : Journal of Virology. 90, 12, p. 5797-5807 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis

Speir, M., Lawlor, K. E., Glaser, S. P., Abraham, G., Chow, S., Vogrin, A., Schulze, K. E., Schuelein, R., O'Reilly, L. A., Mason, K., Hartland, E. L., Lithgow, T., Strasser, A., Lessene, G., Huang, D. C. S., Vince, J. E. & Naderer, T., 24 Feb 2016, In : Nature Microbiology. 1, 3, 9 p., 15034.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Fast track, dynein-dependent nuclear targeting of human immunodeficiency virus Vpr protein: Impaired trafficking in a clinical isolate

Caly, L., Kassouf, V. T., Moseley, G. W., Diefenbach, R. J., Cunningham, A. L. & Jans, D. A., 11 Jan 2016, In : Biochemical and Biophysical Research Communications. 470, 3, p. 735-740 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Feedback from each retinal neuron population drives expression of subsequent fate determinant genes without influencing the cell cycle exit timing

Chi Kei, J. N., Dudczig, S., Currie, P. D. & Jusuf, P. R., 2016, In : The Journal of Comparative Neurology. 524, 13, p. 2553-2566 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Highly stable enzymatic membrane for fast treatment of antibiotic-polluted water

Zhao, Z., Feng, Y., Shamsaei, E., Song, J., Wang, H. & He, L., 2016, In : Journal of Membrane Science. 518, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Human podocyte depletion in association with older age and hypertension

Puelles, V. G., Cullen-McEwen, L. A., Taylor, G. E., Li, J., Hughson, M. D., Kerr, P. G., Hoy, W. E. & Bertram, J. F., 1 Apr 2016, In : American Journal of Physiology-Renal Physiology. 310, 7, p. F656-F668 13 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)