Research output per year
Research output per year
Equipments Details
Description
The Monash Macromolecular Crystallisation Platform is an automated platform for the high-throughput crystallisation of biological macromolecules. Macromolecular crystallography provides unparalleled details of the 3D structures of biological macromolecules, it forms the basis for the rational design of therapeutics. Our facility helps to overcome the common bottleneck in crystallographic structure determination.
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A molecular basis underpinning TRBV28+ T-cell receptor recognition of MR1–antigen
Awad, W. (Leading Author), Gherardin, N. A., Ciacchi, L., Keller, A. N., Liu, L., Fairlie, D. P., McCluskey, J., Godfrey, D. I. & Rossjohn, J., Aug 2025, In: Journal of Biological Chemistry. 301, 8, 14 p., 110416.Research output: Contribution to journal › Article › Research › peer-review
Open Access -
Cigarette smoke components modulate the MR1–MAIT axis
Awad, W., Mayall, J. R., Xu, W., Johansen, M. D., Patton, T., Lim, X. Y., Galvao, I., Howson, L. J., Brown, A. C., Haw, T. J., Donovan, C., Das, S., Albers, G. J., Pai, T. Y., Hortle, E., Gillis, C. M., Hansbro, N. G., Horvat, J. C., Liu, L. & Mak, J. Y. W. & 5 others, , 3 Feb 2025, In: Journal of Experimental Medicine. 222, 2, 25 p., e20240896.Research output: Contribution to journal › Article › Research › peer-review
Open Access6 Citations (Scopus) -
Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells
Prota, G., Berloffa, G., Awad, W. (Leading Author), Vacchini, A., Chancellor, A., Schaefer, V., Constantin, D., Littler, D. R., Colombo, R., Nosi, V., Mori, L., Rossjohn, J. & De Libero, G., 20 May 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 20, 12 p., e2418525122.Research output: Contribution to journal › Article › Research › peer-review
Open Access2 Citations (Scopus)
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Systematic discovery of evolutionary origins and functional diversity of methyltransferases.
Valentin Alvarado, L. (Primary Chief Investigator (PCI)) & Knott, G. (Supervisor)
1/10/25 → 30/09/28
Project: Research
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RNA at facultative heterochromatin: why is it there and how can we use it?
Davidovich, C. (Primary Chief Investigator (PCI))
30/06/25 → 29/06/29
Project: Research
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Inducing essential bacterial enzymes to self-destruct
Xie, S. (Primary Chief Investigator (PCI)), Tilley, L. (Chief Investigator (CI)) & Carter, G. (Chief Investigator (CI))
20/03/25 → 19/03/28
Project: Research