Genome Modification Platform

    Jeanette Rientjes (Manager)Peta Burns (Manager)

Facility/equipment: Facility

  • Location

    23 Innovation Way Clayton 3800

    Australia

Equipments Details

Description

Our platform can fulfill all your requirements for genome modification in today’s experimental organisms, including mouse, rat and other species. Working together with the Australian Phenomics Network (APN) node at Monash and the Monash Animal Research Platform, we deliver a comprehensive service in whole animal genome modification using CRISPR, embryonic stem cell, and transgenic technologies.

Research Output

Indirect presentation in the thymus limits naive and regulatory T-cell differentiation by promoting deletion of self-reactive thymocytes

Yap, J. Y., Wirasinha, R. C., Chan, A., Howard, D. R., Goodnow, C. C. & Daley, S. R., 1 Jul 2018, In : Immunology. 154, 3, p. 522-532 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Evidence that central pathways that mediate defecation utilize ghrelin receptors but do not require endogenous ghrelin

Pustovit, R. V., Callaghan, B., Ringuet, M. T., Kerr, N. F., Hunne, B., Smyth, I. M., Pietra, C. & Furness, J. B., 1 Aug 2017, In : Physiological Reports. 5, 15, 11 p., e13385.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

IL-2 prevents deletion of developing T-regulatory cells in the thymus

Hu, D. Y., Wirasinha, R. C., Goodnow, C. C. & Daley, S. R., Jun 2017, In : Cell Death and Differentiation. 24, 6, p. 1007-1016 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)