Cryo-Electron Microscopy

Projects

Collaborative Network to Define the Molecular Determinants of G Protein Coupled Receptor Clinical Efficacy

Project: Research

Immunobiology and Immunotherapy of Cancer

Project: Research

Novel targeting of the glucagon family of G protein coupled receptors

Project: Research

Molecular basis for stress-induced gene regulation - a model system to understand transcriptional deregulation in cancer and neurological disease

Project: Research

mtDNA release and novel applications for caspase inhibition

Project: Research

Evaluation of therapeutic approaches for FLNC myofibrillar myopathy

Project: Research

Understanding leukocyte function in inflammatory disease

Project: Research

Elucidating the architecture of fibres formed by designed β-amino acid containing peptides

Project: Research

Molecular mechanism for the regulation of Polycomb repressive complex 2

Project: Research

Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions

Project: Research

Molecular determinants of drug binding and selectivity at muscarinic acetylcholine receptors

Project: Research

The role of structure in the formation and properties of glasses.

Project: Research

NOVEL SOLUTIONS FOR ANTIMICROBIAL RESISTANT PATHOGENS

Project: Research

Degradable nanocapsules for thromboprophylaxis and treatment of acute thrombosis

Project: Research

Confocal and single molecule microscopes for Systems Microscopy

Project: Other

NHMRC Research Fellowship

Project: Research

Novel Babesia proteins and their roles in the pathogenesis of tick fever

Project: Research

A structural understanding of class B G protein-coupled receptor function

Project: Research

Smart Targeted Nanoparticles for Diagnosis and Therapy

Project: Research

Pushing the Limits of Fluorescence Microscopy with Adaptive Optics

Project: Research

How do MACPF/CDC proteins punch giant holes in lipid membranes?

Project: Research

An integrative structural biology approach to understanding the SAGA transcriptional master regulator implicated in cancer and development

Project: Research

Nature-inspired electrochemical conversion of nitrogen to ammonia

Project: Research

Next-generation prostate cancer therapies based on precision nanomedicines

Project: Research

Translating membrane proteins into therapeutics; from bedside to bench

Project: Research

Novel targeted Onco-theranostic nanoparticles for personalised therapy and real-time monitoring

Project: Research

A neuro-immune axis regulates beige adipocyte development and function

Project: Research

Structural and functional characterisation of the oncogene P-Rex1

Project: Research

Improving on nature: diversifying glycopeptide antibiotics to kill the bacterial pathogen Staphylococcus aureus

Project: Research

Structural studies of a novel nematocidal protein from the edible fungus, Corprinopsis cinerea

Project: Research

Activation and inhibition of the Plasminogen/Plasmin system

Project: Research

The role of neuronal activity in promoting remyelination of the brain

Project: Research

Mechanism of action of a novel multifunctional bacterial secretion system

Project: Research

An in situ structural study of Drosophila embryonic patterning

Project: Research

Novel genes in skeletal muscle disease

Project: Research

Defining role of inflammatory signals in enhancing motoneuron regeneration

Project: Research

Research Output

Phase-plate cryo-EM structure of a biased agonistbound human GLP-1 receptor-Gs complex

Research output: Contribution to journal › Article › Research › peer-review

The middle fragment of Helicobacter pylori CagA induces Actin rearrangement and triggers its own uptake into gastric epithelial cells

Research output: Contribution to journal › Article › Research › peer-review

Structural characterization of Clostridium sordellii spores of diverse human, animal, and environmental origin and comparison to Clostridium difficile spores

Research output: Contribution to journal › Article › Research › peer-review

Mural lymphatic endothelial cells regulate meningeal angiogenesis in the zebrafish

Research output: Contribution to journal › Article › Research › peer-review

Structure of the adenosine-bound human adenosine A₁ receptor-G_i complex

Research output: Contribution to journal › Article › Research › peer-review

Highly dispersed TiO₂ nanocrystals and WO₃ nanorods on reduced graphene oxide: Z-scheme photocatalysis system for accelerated photocatalytic water disinfection

Research output: Contribution to journal › Article › Research › peer-review

Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract

Research output: Contribution to journal › Article › Research › peer-review

Constructing ultrathin film with "memory" photocatalytic activity from monolayered tungstate nanodots

Research output: Contribution to journal › Article › Research › peer-review

Delivery of femtolitre droplets using surface acoustic wave based atomisation for cryo-EM grid preparation

Research output: Contribution to journal › Article › Research › peer-review

Highly dispersed TiO₂nanocrystals and carbon dots on reduced graphene oxide: Ternary nanocomposites for acceleratedphotocatalytic water disinfection

Research output: Contribution to journal › Article › Research › peer-review

Structure of the poly-C9 component of the complement membrane attack complex

Research output: Contribution to journal › Article › Research › peer-review

Structure and membrane topography of the vibrio-type secretin complex from the type 2 secretion system of enteropathogenic Escherichia coli

Research output: Contribution to journal › Article › Research › peer-review

The first transmembrane region of complement component-9 acts as a brake on its self-assembly

Research output: Contribution to journal › Article › Research › peer-review

Methods in renal research: Measurement of autophagic flux in the renal cortex ex vivo

Research output: Contribution to journal › Review Article › Other › peer-review

Self-assembled enzyme nanoparticles for carbon dioxide capture

Research output: Contribution to journal › Article › Research › peer-review

In Vivo Function of the Chaperonin TRiC in α-Actin Folding during Sarcomere Assembly

Research output: Contribution to journal › Article › Research › peer-review