Australian Translational Medicinal Chemistry Facility (ATMCF)

Facility/equipment: Facility

  • Location

    381 Royal Parade Parkville Victoria 3052

    Australia

Equipments Details

Description

The Australian Translational Medicinal Chemistry Facility (ATMCF) is a purpose-designed, outward-facing, collaborative facility translating new discoveries in disease biology into suitably targeted therapeutics for clinical development.

ATMCF will partner with suitable researchers in disease biology to efficiently and effectively address the multifaceted requirements of drug-discovery.

By working to a suitably defined target product profile (TPP) that addresses an unmet medical need, the complimentary capabilities of the partner and the ATMCF and its other ancillary partners will be combined to achieve a fully integrated drug discovery platform

Research Output

Action plan for hit identification (APHID): KAT6A as a case study

Yi, X., Xue, L., Thomas, T. & Baell, J. B., 1 Mar 2020, In : Future Medicinal Chemistry. 12, 5, p. 423-437 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi

Varghese, S., Rahmani, R., Russell, S., Deora, G. S., Ferrins, L., Toynton, A., Jones, A., Sykes, M., Kessler, A., Eufrásio, A., Cordeiro, A. T., Sherman, J., Rodriguez, A., Avery, V. M., Piggott, M. J. & Baell, J. B., 2020, In : ACS Medicinal Chemistry Letters. 11, 3, p. 278-285 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Novel 1-Methyl-1 H-pyrazole-5-carboxamide Derivatives with Potent Anthelmintic Activity

Le, T. G., Kundu, A., Ghoshal, A., Nguyen, N. H., Preston, S., Jiao, Y., Ruan, B., Xue, L., Huang, F., Keiser, J., Hofmann, A., Chang, B. C. H., Garcia-Bustos, J., Wells, T. N. C., Palmer, M. J., Jabbar, A., Gasser, R. B. & Baell, J. B., 11 Apr 2019, In : Journal of Medicinal Chemistry. 62, 7, p. 3367-3380 14 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)