Zebrafish; Researchers from CSIR Report Findings in Zebrafish (Short Stories on Zebrafish Long Noncoding RNAs)

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2015 JAN 3 (VerticalNews) -- By a News Reporter-Staff News Editor at Ecology, Environment & Conservation Business -- New research on Zebrafish is the subject of a report. According to news originating from Delhi, India, by VerticalNews correspondents, research stated, "The recent re-annotation of the transcriptome of human and other model organisms, using next-generation sequencing approaches, has unravelled a hitherto unknown repertoire of transcripts that do not have a potential to code for proteins. These transcripts have been largely classified into an amorphous class popularly known as long noncoding RNAs (lncRNA)."

Our news journalists obtained a quote from the research from CSIR, "This discovery of lncRNAs in human and other model systems have added a new layer to the understanding of gene regulation at the transcriptional and post-transcriptional levels. In recent years, three independent studies have discovered a number of lncRNAs expressed in different stages of zebrafish development and adult tissues using a high-throughput RNA sequencing approach, significantly adding to the repertoire of genes known in zebrafish. A subset of these transcripts also shows distinct and specific spatiotemporal patterns of gene expression, pointing to a tight regulatory control and potential functional roles in development, organogenesis, and/ or homeostasis."

According to the news editors, the research concluded: "This review provides an overview of the lncRNAs in zebrafish and discusses how their discovery could provide new insights into understanding biology, explaining mutant phenotypes, and helping in potentially modeling disease processes."

For more information on this research see: Short Stories on Zebrafish Long Noncoding RNAs. Zebrafish, 2014;11(6):499-508. Zebrafish can be contacted at: Mary Ann Liebert, Inc, 140 Huguenot Street, 3RD Fl, New Rochelle, NY 10801, USA. (Mary Ann Liebert, Inc. - www.liebertpub.com; Zebrafish - www.liebertpub.com/overview/zebrafish/122/)

The news correspondents report that additional information may be obtained from S. Haque, CSIR Inst Genom & Integrat Biol, GN Ramachandran Knowledge Center Genome Informat, Delhi 110007, India. Additional authors for this research include K. Kaushik, V.E. Leonard, S. Kapoor, A. Sivadas, A. Joshi, V. Scaria and S. Sivasubbu.

Period3 Jan 2015

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