Superbugs have an arsenal of defences – but we've found a new way around them

Press/Media: Research

Description

Researchers have not discovered new antibiotics in decades. But our new research, published today in Nature Microbiology, has found a way to give a second wind to the antibiotics we do have.

It involves the use of viruses that kill bacteria.

The problem

Hospitals are scary, and the longer you remain in them, the greater your risk. Among these risks, hospital-acquired infections are probably the biggest. Each year in Australia, 180,000 patients suffer infections that prolong their hospital stays, increase costs, and, sadly, increase the risk of death.

It sounds absurd – hospitals are supposed to be the cleanest of places. But bacteria are everywhere, and can adapt to the harshest of environments. In hospitals, our increased use of disinfectants and antibiotics has forced these bacteria to evolve to survive. These survivors are called “superbugs”, with an arsenal of tools to resist antibiotics. Superbugs prey on the most vulnerable patients, such as those in intensive care units.

Period12 Jan 2021 → 28 Jan 2021

Media coverage

5

Media coverage

  • TitleSuperbugs have an arsenal of defences - but we’ve found a new way around them
    Degree of recognitionInternational
    Media name/outletNews24
    Media typeWeb
    Country/TerritorySouth Africa
    Date28/01/21
    URLhttps://www.news24.com/health24/medical/infectious-diseases/opinion-superbugs-have-an-arsenal-of-defences-but-weve-found-a-new-way-around-them-20210128
    PersonsTrevor Lithgow, Jeremy Barr
  • TitleResearch uncovers strategy to revert antibiotic-resistance in dangerous superbugs
    Degree of recognitionNational
    Media name/outletThe Medical News
    Media typeWeb
    Country/TerritoryAustralia
    Date18/01/21
    DescriptionA major risk of being hospitalized is catching a bacterial infection. Hospitals, especially areas including intensive care units and surgical wards, are teeming with bacteria, some of which are resistant to antibiotics - they are infamously known as ‘superbugs’. Superbug infections are difficult and expensive to treat, and can often lead to dire consequences for the patient.

    Now, new research published today in the prestigious journal Nature Microbiology has discovered how to revert antibiotic-resistance in one of the most dangerous superbugs. The strategy involves the use of bacteriophages (also known as ‘phages’).
    URLhttps://www.news-medical.net/news/20210118/Research-uncovers-strategy-to-revert-antibiotic-resistance-in-dangerous-superbugs.aspx
    PersonsTrevor Lithgow, Jeremy Barr
  • TitleBreakthrough against antibiotic-resistance
    Degree of recognitionInternational
    Media name/outletScienceDaily
    Media typeWeb
    Country/TerritoryUnited States of America
    Date12/01/21
    DescriptionA major risk of being hospitalised is catching a bacterial infection.

    Hospitals, especially areas including intensive care units and surgical wards, are teeming with bacteria, some of which are resistant to antibiotics -- they are infamously known as 'superbugs'.

    Superbug infections are difficult and expensive to treat, and can often lead to dire consequences for the patient.

    Now, new research published today in the journal Nature Microbiology has discovered how to revert antibiotic-resistance in one of the most dangerous superbugs.
    URLhttps://www.sciencedaily.com/releases/2021/01/210112085355.htm
    PersonsTrevor Lithgow, Jeremy Barr
  • TitleSuperbugs have an arsenal of defences – but we've found a new way around them
    Degree of recognitionNational
    Media name/outletMonash Lens
    Media typeWeb
    Country/TerritoryAustralia
    Date12/01/21
    URLhttps://lens.monash.edu/@jeremy-barr/2021/01/12/1382699/superbugs-have-an-arsenal-of-defences-but-weve-found-a-new-way-around-them
    PersonsTrevor Lithgow, Jeremy Barr
  • TitleMonash University leads breakthrough against antibiotic-resistance
    Degree of recognitionInternational
    Media name/outletEurekaAlert
    Media typeWeb
    Country/TerritoryUnited States of America
    Date12/01/21
    DescriptionA major risk of being hospitalised is catching a bacterial infection.

    Hospitals, especially areas including intensive care units and surgical wards, are teeming with bacteria, some of which are resistant to antibiotics - they are infamously known as 'superbugs'.

    Superbug infections are difficult and expensive to treat, and can often lead to dire consequences for the patient.

    Now, new research published today in the prestigious journal Nature Microbiology has discovered how to revert antibiotic-resistance in one of the most dangerous superbugs.

    The strategy involves the use of bacteriophages (also known as 'phages').

    "Phages are viruses, but they cannot harm humans," said lead study author Dr Fernando Gordillo Altamirano, from the Monash University School of Biological Sciences.

    "They only kill bacteria."
    URLhttps://www.eurekalert.org/pub_releases/2021-01/mu-mul011021.php
    PersonsTrevor Lithgow, Jeremy Barr

Media contributions

1

Media contributions