Study Findings on Drug Delivery Systems Are Outlined in Reports from Faculty of Pharmacy (Recent Advances in Non-Invasive Delivery of Macromolecules using Nanoparticulate Carriers System)

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2017 APR 15 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- Data detailed on Drugs and Therapies - Drug Delivery Systems have been presented. According to news originating from New Delhi, India, by NewsRx correspondents, research stated, "The drug delivery of macromolecules such as proteins and peptides has become an important area of research and represents the fastest expanding share of the market for human medicines. The most common method for delivering macromolecules is parenterally."

Our news journalists obtained a quote from the research from the Faculty of Pharmacy, "However parenteral administration of some therapeutic macromolecules has not been effective because of their rapid clearance from the body. As a result, most macromolecules are only therapeutically useful after multiple injections, which causes poor compliance and systemic side effects. Therefore, there is a need to improve delivery of therapeutic macromolecules to enable non-invasive delivery routes, less frequent dosing through controlled-release drug delivery, and improved drug targeting to increase efficacy and reduce side effects. Non-invasive administration routes such as intranasal, pulmonary, transdermal, ocular and oral delivery have been attempted intensively by formulating macromolecules into nanoparticulate carriers system such as polymeric and lipidic nanoparticles. This review discusses barriers to drug delivery and current formulation technologies to overcome the unfavorable properties of macromolecules via non-invasive delivery (mainly intranasal, pulmonary, transdermal oral and ocular) with a focus on nanoparticulate carrier systems."

According to the news editors, the research concluded: "This review also provided a summary and discussion of recent data on non-invasive delivery of macromolecules using nanoparticulate formulations."

For more information on this research see: Recent Advances in Non-Invasive Delivery of Macromolecules using Nanoparticulate Carriers System. Current Pharmaceutical Design, 2017;23(3):440-453. Current Pharmaceutical Design can be contacted at: Bentham Science Publ Ltd, Executive Ste Y-2, PO Box 7917, Saif Zone, 1200 Br Sharjah, U Arab Emirates. (Bentham Science Publishers -; Current Pharmaceutical Design -

The news correspondents report that additional information may be obtained from J. Ali, Jamia Hamdard, Fac Pharm, Dept. of Pharmaceut, New Delhi 110062, India. Additional authors for this research include S. Haque, R. Sheshala, L.W. Meng, V.S. Meka and J. Ali.

Keywords for this news article include: New Delhi, India, Asia, Drugs and Therapies, Article Review, Drug Delivery Systems, Faculty of Pharmacy.

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Period15 Apr 2017

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