Signalling under the microscope

  • Sebastian Furness

Press/Media: Expert Comment


News & Views article on:

Liang YL, Khoshouei M, Radjainia M, Zhang Y, Glukhova A, Tarrasch J, Thal DM, Furness SGB, Christopoulos G, Coudrat T, Danev R, Baumeister W, Miller LJ, Christopoulos A, Kobilka BK, Wootten D, Skiniotis G, Sexton PM. Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature. 2017 Jun 1;546(7656):118-123. doi: 10.1038/nature22327. Epub 2017 Apr 24. PubMed PMID: 28437792; PubMed Central PMCID: PMC5832441.


Period1 Jun 2017

Media contributions


Media contributions

  • TitleStructural biology: Signalling under the microscope.
    Degree of recognitionInternational
    Media name/outletNature
    Media typePrint
    DescriptionG-protein-coupled receptors are biological targets for drug discovery. Developments in cryo-electron microscopy have enabled the solution of the structure of a class B receptor in complex with its signalling protein. Two biologists and a microscopist explain the exciting implications of this work
    Producer/AuthorChing-Ju Tsai, Joerg Standfuss & Robert M. Glaeser
    PersonsSebastian Furness