Description
Dr Iain Hay from Monash Biomedicine Discovery Institute
Published recently in mBio, and with media coverage including reports on PhysOrg, ICT Today , Bright Surf and DotMed,a study led by Monash BDI's Professor Trevor Lithgow and Dr Iain Hay has created the first high-resolution structure depicting a crucial part of the ‘superbug’ Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image, developed using the Titan Krios microscope, identifies the ‘nanomachine’ used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this.
| Period | 19 Oct 2017 → 20 Oct 2017 |
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Media coverage
5
Media coverage
Title Researchers Reveal How Superbug Secretes It’s Toxin Degree of recognition International Media name/outlet Technology Networks Media type Web Country/Territory Australia Date 20/10/17 Description Monash University’s Biomedicine Discovery Institute (BDI) researchers have created the first high-resolution structure depicting a crucial part of the ‘superbug’ Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image identifies the ‘nanomachine’ used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this.
P. aeruginosa is one of a number of bacteria developing an alarming resistance to multiple drugs, raising concerns worldwide about the emergence of pan-resistant organisms.
Its virulence is due largely to the ability of the bacteria to secrete a suite of toxins and enzymes infecting the host environment.URL https://www.technologynetworks.com/drug-discovery/news/researchers-reveal-how-superbug-secretes-its-toxin-293437 Persons Iain Hay Title Scientists reveal 'superbug's' artillery Degree of recognition International Media name/outlet bright surf Country/Territory Australia Date 19/10/17 Description Monash University's Biomedicine Discovery Institute (BDI) researchers have created the first high-resolution structure depicting a crucial part of the 'superbug' Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image identifies the 'nanomachine' used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this.
P. aeruginosa is one of a number of bacteria developing an alarming resistance to multiple drugs, raising concerns worldwide about the emergence of pan-resistant organisms.
Its virulence is due largely to the ability of the bacteria to secrete a suite of toxins and enzymes infecting the host environment.
In a paper published this week in the online journal mBio, BDI researchers investigated a protein nanomachine on the surface of the bacterial cells responsible for the secretion of these toxins. The nanomachine, called the Type II secretion system, is responsible for the secretion of P. aureginosa's most toxic virulence factor, Exotoxin A.URL https://www.brightsurf.com/news/article/101917441743/scientists-reveal-superbugs-artillery.html Persons Iain Hay Title Scientists create the first high-resolution structure depicting superbug's artillery Degree of recognition International Country/Territory Australia Date 19/10/17 Description Monash University's Biomedicine Discovery Institute (BDI) researchers have created the first high-resolution structure depicting a crucial part of the 'superbug' Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image identifies the 'nanomachine' used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this. URL https://www.dotmed.com/news/story/39801 Persons Iain Hay Title https://phys.org/news/2017-10-scientists-reveal-superbug-artillery.html Degree of recognition International Media name/outlet Phys.org Country/Territory Australia Date 19/10/17 Description Monash University's Biomedicine Discovery Institute (BDI) researchers have created the first high-resolution structure depicting a crucial part of the 'superbug' Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image identifies the 'nanomachine' used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this.
Read more at: https://phys.org/news/2017-10-scientists-reveal-superbug-artillery.html#jCpURL https://phys.org/news/2017-10-scientists-reveal-superbug-artillery.html Persons Trevor Lithgow Title Scientists Reveal Superbug's Artillery Degree of recognition International Media name/outlet Infection Control Today Country/Territory Australia Date 19/10/17 Description Oct 19, 2017
Monash University's Biomedicine Discovery Institute (BDI) researchers have created the first high-resolution structure depicting a crucial part of the 'superbug' Pseudomonas aeruginosa, classified by the WHO as having the highest level threat to human health. The image identifies the 'nanomachine' used by the highly virulent bacteria to secrete toxins, pointing the way for drug design targeting this.URL https://www.infectioncontroltoday.com/pathogens/scientists-reveal-superbugs-artillery Persons Iain Hay
Media contributions
1Media contributions
Title Superbug's Artillery Revealed: Nanomachine Secretes Toxins Degree of recognition Regional Media name/outlet Pittwater News Media type Web Country/Territory Australia Date 19/10/17 URL www.pittwateronlinenews.com/Inbox-and-Environment-News-Issue-334.php Persons Iain Hay