Media coverage
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Media coverage
Title CD4+ T cells: a potential player in renal fibrosis Degree of recognition International Media name/outlet Kidney International Media type Print Country/Territory United Kingdom Date 1/01/10 Description T cells have a well-described role in renal injury, which leads to the secondary development of renal fibrosis. It has generally been assumed that this fibrotic response is an indirect consequence of T cell-mediated renal injury, rather than T cells' being directly involved in fibrosis. Tapmeier et al. now provide evidence that CD4(+) T cells promote interstitial fibrosis in the obstructed mouse kidney in a mechanism that appears to dissociate myofibroblast accumulation and matrix deposition. Producer/Author David J. Nikolic-Paterson URL https://www.kidney-international.org/article/S0085-2538(15)54556-0/fulltext Persons Thomas Tapmeier
Keywords
- Renal Fibrosis
- T Cells
- Chronic Kidney Disease