CD4+ T cells: a potential player in renal fibrosis

Press/Media: Expert Comment

Description

Comment on my article on the role of T cells in renal fibrosis.

Period1 Jan 2010

Media coverage

1

Media coverage

  • TitleCD4+ T cells: a potential player in renal fibrosis
    Degree of recognitionInternational
    Media name/outletKidney International
    Media typePrint
    CountryUnited Kingdom
    Date1/01/10
    DescriptionT cells have a well-described role in renal injury, which leads to the secondary development of renal fibrosis. It has generally been assumed that this fibrotic response is an indirect consequence of T cell-mediated renal injury, rather than T cells' being directly involved in fibrosis. Tapmeier et al. now provide evidence that CD4(+) T cells promote interstitial fibrosis in the obstructed mouse kidney in a mechanism that appears to dissociate myofibroblast accumulation and matrix deposition.
    Producer/AuthorDavid J. Nikolic-Paterson
    URLhttps://www.kidney-international.org/article/S0085-2538(15)54556-0/fulltext
    PersonsThomas Tapmeier