CD4+ T cells: a potential player in renal fibrosis

Press/Media: Expert Comment


Comment on my article on the role of T cells in renal fibrosis.

Period1 Jan 2010

Media coverage


Media coverage

  • TitleCD4+ T cells: a potential player in renal fibrosis
    Degree of recognitionInternational
    Media name/outletKidney International
    Media typePrint
    Country/TerritoryUnited Kingdom
    DescriptionT cells have a well-described role in renal injury, which leads to the secondary development of renal fibrosis. It has generally been assumed that this fibrotic response is an indirect consequence of T cell-mediated renal injury, rather than T cells' being directly involved in fibrosis. Tapmeier et al. now provide evidence that CD4(+) T cells promote interstitial fibrosis in the obstructed mouse kidney in a mechanism that appears to dissociate myofibroblast accumulation and matrix deposition.
    Producer/AuthorDavid J. Nikolic-Paterson
    PersonsThomas Tapmeier


  • Renal Fibrosis
  • T Cells
  • Chronic Kidney Disease