Project Coordinator - Monash Brain and Behaviour Twins Study

Activity: Other Teaching Engagements and non-HDR SupervisionsOther

Description

The Monash Brain and Behaviur Twins Study was developed by me, in collaboration with the PI Laureate Professor Alex Fornito, and Professor Robert Krueger (ranked in the top 100 psychologists in the world), to estimate the proportion of variance explained across different components of the Hierarchical Taxonomy of Psychopathology (HiTOP) model by genetic and environmental influences. To do this, we recruited a sample of 697 twin pairs (542 monozygotic and 155 dizygotic) from Twins Research Australia (TRA) registry, with whom I worked closely, and had participants complete the battery of psychopathology questionnaires capturing the model and fluctuations in their mood sleep, stress, and substance use intake for 28 days following. In a follow-up study, we collected saliva for genotyping. No previous behavioural genetics studies have been applied to the HiTOP model or so richly phenotyped a twin sample and the project promises to yield unique insights into the genetic and environmental influences on psychopathology, with implications for further research and treatments.
Period8 Jul 20201 May 2025
Held atTwins Research Australia, Australia, Victoria
Degree of RecognitionNational