Dana-Farber Cancer Institute (External organisation)

  • Fletcher, A. (Inventor)
  • Biju Parekkadan (Inventor)
  • Shannon J Turley (Member)

Activity: Industry, Government and Philanthropy Engagement and Partnerships › Patents › Patent

Description

ISOLATION AND USE OF HUMAN LYMPHOID ORGAN-DERIVED SUPPRESSIVE STROMAL CELLS
WO2013142186A1 WIPO (PCT), KR102100307B1, AU2018201195B2, CA2867487C, EP2827879B1, JP6346602B2, CN104349785A, HK1206277A1, US20200061118A1

A method for suppressing an immune response is provided. The method involves administration of isolated lymphoid tissue-derived suppressive stromal cells (LSSC) to a subject in need of such treatment in an amount effective to suppress the immune response in the subject. The invention also involves a method to isolate LSSC by digesting lymphoid tissue fragments using a combination of an enzyme mix and agitation and then collecting the LSSC. Pharmaceutical preparations comprising LSSC are also provided.
Period27 Feb 2020 → …
Held atDana-Farber Cancer Institute, United States of America, Massachusetts
Degree of RecognitionInternational

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