Baker Heart and Diabetes Institute (External organisation)

Description

Methods and compositions for treating disorders of the extracellular matrix

Abstract: The present invention provides a method for altering the level of an extracellular matrix (ECM) protein produced by a cell, the method including modulating expression or activity of a cell division auto antigen (CDA). The Applicants have surprisingly found that a CDA is involved in a pathway that controls the level of ECM protein produced by mammalian cells. The invention has relevance to a number of ECM-related disorders such as renal fibrosis and atherosclerosis.

WO2005002614A1 - WIPO (PCT)

Period	13 Jan 2005
Held at	Baker Heart and Diabetes Institute, Australia, Victoria
Degree of Recognition	International